Metabolism News and Research

Latest Metabolism News and Research

Disturbances in the body’s carbon monoxide metabolism linked to circadian disruption

Chronobiologists from Charité - Universitätsmedizin Berlin have shown that the body's carbon monoxide metabolism is closely linked to the body's circadian (internal) clock.

7 Dec 2016

Enzyme that cleaves beta carotene may control testosterone levels

An enzyme that converts the dietary carotenoid beta carotene into vitamin A in the body may also regulate testosterone levels and growth of the prostate, a new study found.

7 Dec 2016

Detecting inflammation in diabetic patients

As well as presenting with high blood glucose, diabetic patients have chronic low-grade inflammation, which can be measured by a range of inflammatory markers such as so-called high-sensitive CRP, TNFa and IL-6 as well as a full blood cell count.

7 Dec 2016

Biochemists uncover how potential diabetes drugs interact with LRH-1 protein

Imagine a key that opens a pin tumbler lock. A very similar key can also fit into the lock, but upside down in comparison to the first key.

6 Dec 2016

Small fat-burning molecule could help combat global epidemic of obesity

A small molecule could provide valuable help in combating the global epidemic of obesity.

6 Dec 2016

Signaling pathway in fat cells may provide key to better treatments for obesity, Penn research finds

A signaling pathway in fat cells may one day provide the key to better treatments for obesity, according to new research by scientists in the Perelman School of Medicine at the University of Pennsylvania.

6 Dec 2016

Researchers develop new microfluidic device to study brain inflammation

The blood-brain barrier is a network of specialized cells that surrounds the arteries and veins within the brain. It forms a unique gateway that both provides brain cells with the nutrients they require and protects them from potentially harmful compounds.

6 Dec 2016

Gut microbes may play important role in exacerbated post-dieting weight gain

Following a successful diet, many people are dismayed to find their weight rebounding - an all-too-common phenomenon termed "recurrent" or "yo-yo" obesity.

5 Dec 2016

Research unlocks potential new therapies for inflammatory diseases

Macrophages are frontline cells in our immune system. They detect microbial invaders and also tissue injury and then mount an appropriate response needed to clear the infection and repair the damaged tissue.

5 Dec 2016

Sperm tail enzymes inspire nanobiotechnology

Just like workers in a factory, enzymes can create a final product more efficiently if they are stuck together in one place and pass the raw material from enzyme to enzyme, assembly line-style.

2 Dec 2016

New drug receives FDA approval to reduce risk of cardiovascular death in adults with diabetes

The U.S. Food and Drug Administration today approved a new indication for Jardiance (empagliflozin) to reduce the risk of cardiovascular death in adult patients with type 2 diabetes mellitus and cardiovascular disease.

2 Dec 2016

Many women dissatisfied with length of time for diagnosis of PCOS, survey finds

A large international survey of women with a common condition called polycystic ovary syndrome (PCOS), which is characterized by reproductive and metabolic problems, found nearly two in three were dissatisfied with the length of time they waited and the number of healthcare professionals they had to see before they received a diagnosis, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

1 Dec 2016

$Experts explore if DXA-derived measurements could predict fracture risk in diabetic patients$

Experts explore if DXA-derived measurements could predict fracture risk in diabetic patients

Increased risk of fracture has been shown to be one of the complications arising from longstanding diabetes. With the worldwide increase in Type 2 Diabetes (T2D), in part due to aging populations, there is also increasing concern about how to identify and manage patients with diabetes who are at high risk of osteoporotic fracture.

1 Dec 2016

Bone density could be one of early indicators of brain degeneration in Alzheimer's disease

Researchers at NEOMED have just identified a major connection between areas of the brainstem - the ancient area that controls mood, sleep and metabolism - and detrimental changes to bone in a preclinical model of Alzheimer's disease (AD).

1 Dec 2016

PCSK9 and HMGCR genetic variations that lower bad cholesterol affect risk of cardiovascular events

In a new study published in the December 1, 2016 issue of The New England Journal of Medicine, researchers at Brigham and Women's Hospital, and a collaboration of international researchers, studied variants in the genes encoding HMGCR and PCSK9 that affect cholesterol levels, and found that variants that lowered LDL (or "bad") cholesterol in each gene were associated with nearly identical protective effects on the risk of cardiovascular events per unit reduction in LDL cholesterol.

30 Nov 2016

Researchers use microbubbles and ultrasound to transport drugs across blood–brain barrier

The impassable blood-brain barrier prevents microorganisms from entering our brain, however it also blocks medicines that could help treat Parkinson's, Alzheimer's and other neurodegenerative diseases.

30 Nov 2016

Iron deficiency: an interview with Dr Thierry Teil

Iron deficiency is, in fact, one of the most common nutritional disorders. It affects between three and five billion people, which is between half and two-thirds of the world population (about seven billion). Iron deficiency anemia is a subset of iron deficiency, that is about two billion people according to the WHO...

From CSL Ltd 30 Nov 2016

Mildly elevated body iron contributes to prevalence and incidence of type 2 diabetes

Even mildly elevated body iron contributes to the prevalence and incidence of type 2 diabetes, according to research from the University of Eastern Finland.

30 Nov 2016

Researchers develop virtual liver model to better understand metabolism of non-prescription painkiller

Researchers at Indiana University's Biocomplexity Institute have developed a virtual model of the human liver to better understand how the organ metabolizes acetaminophen, a common non-prescription painkiller and fever-reducer used in over-the-counter drugs such as Tylenol.

29 Nov 2016

Scientists create comprehensive computational metabolic models for different gut microbes

Hundreds of different bacterial species live in the human gut, helping us to digest our food. The metabolic processes of these bacteria are not only tremendously important to our health -- they are also tremendously complex.

29 Nov 2016

Metabolism News and Research

Latest Metabolism News and Research

Disturbances in the body’s carbon monoxide metabolism linked to circadian disruption

Enzyme that cleaves beta carotene may control testosterone levels

Detecting inflammation in diabetic patients

Biochemists uncover how potential diabetes drugs interact with LRH-1 protein

Small fat-burning molecule could help combat global epidemic of obesity

Signaling pathway in fat cells may provide key to better treatments for obesity, Penn research finds

Researchers develop new microfluidic device to study brain inflammation

Gut microbes may play important role in exacerbated post-dieting weight gain

Research unlocks potential new therapies for inflammatory diseases

Sperm tail enzymes inspire nanobiotechnology

New drug receives FDA approval to reduce risk of cardiovascular death in adults with diabetes

Many women dissatisfied with length of time for diagnosis of PCOS, survey finds

Experts explore if DXA-derived measurements could predict fracture risk in diabetic patients

Bone density could be one of early indicators of brain degeneration in Alzheimer's disease

PCSK9 and HMGCR genetic variations that lower bad cholesterol affect risk of cardiovascular events

Researchers use microbubbles and ultrasound to transport drugs across blood–brain barrier

Iron deficiency: an interview with Dr Thierry Teil

Mildly elevated body iron contributes to prevalence and incidence of type 2 diabetes

Researchers develop virtual liver model to better understand metabolism of non-prescription painkiller

Scientists create comprehensive computational metabolic models for different gut microbes

Transforming Cardiovascular Care: Insights from Mina Makar at AstraZeneca

Clue's CEO Rhiannon White on the Future of Femtech and PCOS

Freezing Point Osmometry in Life Science Applications