Metabolism News and Research

Latest Metabolism News and Research

Scientists discover key cellular mechanism behind side-effects of antipsychotics

Since their development in the 1950s, antipsychotic drugs have been widely used to treat psychoses and neuropsychiatric disorders like schizophrenia. A debilitating side-effect of these drugs called parkinsonism limits their efficacy.

7 Jul 2016

Minoryx Therapeutics initiates phase 1 clinical trial of MIN-102

Minoryx Therapeutics, a drug development company specialized in the discovery and development of new drugs for orphan diseases, today announces the initiation of its first-in-man Phase 1 clinical trial for its lead compound MIN-102.

7 Jul 2016

Liraglutide drug lowers blood sugar levels in diabetic patients taking large doses of insulin

When Amy Sweat was 19 years old, while she was in the hospital recovering from surgery, she was diagnosed with Type 2 diabetes. Ms. Sweat was treated for her diabetes, first on oral drugs, then on increasingly larger doses of insulin, but the years went by and she never was able to achieve good blood sugar control.

6 Jul 2016

Scientists discover X-chromosome-inherited type of osteogenesis imperfecta

Researchers from the University of Zurich and University Children's Hospital Zurich have discovered the first X-chromosome-inherited type of the congenital disease osteogenesis imperfecta, also known as brittle-bone disease.

6 Jul 2016

Deuteration offers alternative chorea treatment for Huntington disease patients

Treatment with a deuterated form of tetrabenazine has resulted in improved motor signs among patients with Huntington disease, making it a potential treatment for chorea, trial findings show.

6 Jul 2016

Study finds link between cortisol levels and obesity in patients with bipolar disorder or recurrent depressions

Low levels of the stress hormone cortisol are linked to obesity, high levels of fat in the blood and metabolic syndrome among patients with recurrent depressions or bipolar disorder. This according to a study at Umea University in Sweden published in the Journal of Affective Disorders.

5 Jul 2016

Study demonstrates role of leukocyte activation receptor CD69 in development of psoriasis

Scientists at the Centro de Investigaciones Cardiovasculares Carlos III have defined the key role of an immune-system receptor in the development of psoriasis, suggesting that it could serve as a therapeutic target for the control of this disease.

5 Jul 2016

Obesity not linked to increased insulation in mice, say researchers

Carrying excess fat does not contribute to a warmer body in obese mice, a new study on the insulating effects of fat finds. The article is published in the American Journal of Physiology—Endocrinology and Metabolism.

5 Jul 2016

Novel anti-interleukin 1-alpha antibody shows promise in treating advanced colorectal cancer patients

A novel anti-interleukin 1-alpha antibody has shown a significant impact on symptoms, and a high level of safety and tolerability in patients with advanced colorectal cancer, according to phase III data presented at the European Society for Medical Oncology's 18th World Congress of Gastrointestinal Cancer in Barcelona, Spain.

4 Jul 2016

Study links proteins involved in cell division to insulin signaling

Proteins that play key roles in the timing of cell division also moonlight in regulating blood sugar levels, UT Southwestern Medical Center researchers have found.

1 Jul 2016

Study sheds more light on how bacteria rapidly causes infectious diseases

Researchers at Umea University are first to discover that bacteria can multiply disease-inducing genes which are needed to rapidly cause infection.

1 Jul 2016

Study assesses prevalence of delirium among survivors of cardiac arrest treated with hypothermia

A study in the American Journal of Critical Care found a remarkably high prevalence of delirium in a small cohort of critically ill patients treated with therapeutic hypothermia after cardiac arrest.

1 Jul 2016

Advances in inhaled drug delivery: an interview with Dr Robert Clarke

Delivering drugs to the lungs via inhalation has a number of potential advantages over traditional routes of administration like pills or injections. For treating pulmonary diseases, the obvious logic we are applying is topical delivery to the airways via inhalation.

1 Jul 2016

Itaconate can suppress pro-inflammatory activity of macrophages

An international group of scientists from US, Canada, Germany and Russia has revealed a substance produced in humans that can suppress the pro-inflammatory activity of macrophages - specific cells of immune system.

1 Jul 2016

Researchers develop in vitro model system for investigating etiology of NAFLD

Researchers from the Institute for Stem Cell Research and Regenerative Medicine at the University Clinic of Düsseldorf have established an in vitro model system for investigating nonalcoholic fatty liver disease (NAFLD).

30 Jun 2016

Excess or insufficient sleep may increase diabetes risk in men

Men who sleep either fewer or more hours than average may face a greater risk of developing diabetes, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

30 Jun 2016

Scientists reveal metabolic reasons why low calorie diets may lead to longer life

Overeating can lead to health issues that can shorten one's life, such as obesity, diabetes and heart disease.

30 Jun 2016

Testosterone therapy improves sexual activity in older men

Older men with low libido and low testosterone levels showed more interest in sex and engaged in more sexual activity when they underwent testosterone therapy, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

30 Jun 2016

Regular physical activity improves brain power, academic prowess in children

A consensus statement which includes a University of Exeter researcher says exercise boosts kids' and young people's brain power and academic prowess.

29 Jun 2016

Researchers develop new computational method to track colorectal cancer progression

Team of researchers elaborated a computational method to track the progress of the colorectal cancer. It is a scientific advance that can bring new perspectives to discover the factors that push this pathology and the selection of efficient therapies.

29 Jun 2016

Metabolism News and Research

Latest Metabolism News and Research

Scientists discover key cellular mechanism behind side-effects of antipsychotics

Minoryx Therapeutics initiates phase 1 clinical trial of MIN-102

Liraglutide drug lowers blood sugar levels in diabetic patients taking large doses of insulin

Scientists discover X-chromosome-inherited type of osteogenesis imperfecta

Deuteration offers alternative chorea treatment for Huntington disease patients

Study finds link between cortisol levels and obesity in patients with bipolar disorder or recurrent depressions

Study demonstrates role of leukocyte activation receptor CD69 in development of psoriasis

Obesity not linked to increased insulation in mice, say researchers

Novel anti-interleukin 1-alpha antibody shows promise in treating advanced colorectal cancer patients

Study links proteins involved in cell division to insulin signaling

Study sheds more light on how bacteria rapidly causes infectious diseases

Study assesses prevalence of delirium among survivors of cardiac arrest treated with hypothermia

Advances in inhaled drug delivery: an interview with Dr Robert Clarke

Itaconate can suppress pro-inflammatory activity of macrophages

Researchers develop in vitro model system for investigating etiology of NAFLD

Excess or insufficient sleep may increase diabetes risk in men

Scientists reveal metabolic reasons why low calorie diets may lead to longer life

Testosterone therapy improves sexual activity in older men

Regular physical activity improves brain power, academic prowess in children

Researchers develop new computational method to track colorectal cancer progression

Transforming Cardiovascular Care: Insights from Mina Makar at AstraZeneca

Clue's CEO Rhiannon White on the Future of Femtech and PCOS

Freezing Point Osmometry in Life Science Applications