Metabolism News and Research

Latest Metabolism News and Research

Neutralizing acidic tumor environment increases efficacy of immune-targeting cancer therapies

Cancer cells have the ability to grow in an acidic tumor environment that is detrimental to other cells, including immune cells. In a Cancer Research cover article published this week, Moffitt Cancer Center reported that neutralizing the acidic tumor environment increases the efficacy of several immune-targeting cancer therapies.

19 Mar 2016

Inhibiting cholesterol esterification can potentiate antitumor activity of killer T cells

As key players in the immune system, T cells provide tumor surveillance and have direct antitumor effects. However, tumors can escape T-cell attack through various mechanisms in the tumor microenvironment. Reactivating the antitumor effects of T cells has shown great clinical benefits in treating various cancers.

18 Mar 2016

Could prebiotics benefit early life brain development? An interview with Dr Phil Burnet

Galacto-oligosaccharides are essentially sugar or saccharide molecules that have been joined together into short polymer chains.

16 Mar 2016

Researchers explore problem of obesity from the inside out

In the last 40 years, obesity has more than doubled around the world. In the United States, the average American is more than 24 pounds heavier today than in 1960. Researchers at Baylor College of Medicine, Technion-Israel Institute of Technology and the University of Washington are studying the problem of obesity from the inside out.

16 Mar 2016

Diet-induced obesity, diabetes can be epigenetically inherited by offspring, say scientists

Scientists at Helmholtz Zentrum München, in collaboration with researchers from Technical University of Munich and the German Center for Diabetes Research, have shown that diet-induced obesity and diabetes can be epigenetically inherited by the offspring via both the oocytes and the sperm.

16 Mar 2016

Decreased dietary diversity linked to reduced microbiotic richness

Changes in farming practices over the last 50 years have resulted in decreased agro-diversity which, in turn, has resulted in decreased dietary diversity. The significant impact of this change in dietary richness on human health is the topic of an insightful perspective in Molecular Metabolism by Mark Heiman, MicroBiome Therapeutics and Frank Greenway, Pennington Biomedical Research Center

15 Mar 2016

Real-time imaging method may lead to improved stroke care

According to the American Heart Association, ischemic strokes account for nearly 90 percent of all strokes. They occur when a blocked artery prevents blood from getting to the brain and usually result in long-term disability or death. Now, a team of researchers led by the University of Missouri School of Medicine has developed a new, real-time method of imaging molecular events after strokes - a finding that may lead to improved care for patients.

15 Mar 2016

Researchers provide new mechanism for age-related macular degeneration

Age-related macular degeneration (AMD) is the leading cause of visual impairment in people over 50 in developed countries. Although this condition affects up to 20% of people between the ages of 65 and 75, what drives abnormal blood vessels to invade the retina is unknown.

15 Mar 2016

Drugs to help energy-starved photoreceptors offers new avenue for treating AMD , MacTel

New research from Boston Children's Hospital could potentially change how doctors approach two blinding diseases: 'Wet' age-related macular degeneration (AMD), the leading cause of blindness in the elderly, and macular telangiectasia (MacTel).

15 Mar 2016

People with type 2 diabetes, OSA may not experience improved glycemic control with CPAP

People with type 2 diabetes and obstructive sleep apnea (OSA) may not experience improved glycemic control by using continuous positive airway pressure, or CPAP, as some studies have suggested, according to the results of a randomized, controlled trial published online ahead of print in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine.

13 Mar 2016

Delivering microRNAs in cancer treatment: an interview with Dr Conde and Prof Artzi

microRNAs (miRs) are small endogenous noncoding RNA molecules (20–23 nucleotides) derived from imperfectly paired hairpin RNA structures naturally encoded in the genome that act specifically as triggering molecules to control translational repression or mRNA degradation.

11 Mar 2016

Metabolism News and Research

Latest Metabolism News and Research

Neutralizing acidic tumor environment increases efficacy of immune-targeting cancer therapies

Inhibiting cholesterol esterification can potentiate antitumor activity of killer T cells

Could prebiotics benefit early life brain development? An interview with Dr Phil Burnet

Researchers explore problem of obesity from the inside out

Diet-induced obesity, diabetes can be epigenetically inherited by offspring, say scientists

Decreased dietary diversity linked to reduced microbiotic richness

Real-time imaging method may lead to improved stroke care

Researchers provide new mechanism for age-related macular degeneration

Drugs to help energy-starved photoreceptors offers new avenue for treating AMD , MacTel

People with type 2 diabetes, OSA may not experience improved glycemic control with CPAP

Delivering microRNAs in cancer treatment: an interview with Dr Conde and Prof Artzi

PKM2 enzyme plays major role in early steps of wound healing

STING agonists developed to induce cellular death in B cell malignancies

Brown fat may help to keep blood sugar steady in adults

CYP3A7 gene may over-activate metabolism, reduce effectiveness of cancer treatments

Scientists discover novel drug candidate to treat breast cancer, lung cancer and melanoma

Bioengineers introduce CORDA algorithm to find new therapeutic targets for cancer

Exercise more effective than food restriction in helping reduce daily calorie consumption

Metabolic syndrome treatment benefits MS patients

Antidepressants may play role in dental implant failure

Transforming Cardiovascular Care: Insights from Mina Makar at AstraZeneca

Clue's CEO Rhiannon White on the Future of Femtech and PCOS

Freezing Point Osmometry in Life Science Applications