Metabolism News and Research

Latest Metabolism News and Research

Four microRNAs appear to play critical roles in controlling cholesterol, triglyceride metabolism

Four tiny segments of RNA appear to play critical roles in controlling cholesterol and triglyceride metabolism. In their report receiving advance online publication in Nature Medicine, a Massachusetts General Hospital-based research team describes finding how these microRNAs could reduce the expression of proteins playing key roles in the generation of beneficial HDL cholesterol, the disposal of artery-clogging LDL cholesterol, control of triglyceride levels and other risk factors of cardiovascular disease.

27 Oct 2015

Low-weight, high-repetition resistance training increases bone density in adults

A new research study published in The Journal of Sports Medicine and Physical Fitness finds that low-weight, high-repetition resistance training increases bone mineral density in adults, challenging assumptions that heavy weight-training is required to build bone mineral density. Participants who completed the study experienced up to 8 percent bone mineral density increases in the legs, pelvis, arms and spine.

27 Oct 2015

Endocannabinoids can affect development of baby's pancreas

According to the latest research results from the Medical University of Vienna, endocannabinoids, cannabis-like substances produced by the body itself, can affect the development of a baby's pancreas. The study also highlights the importance of diet during pregnancy for the foetal pancreas to form.

23 Oct 2015

Discovery may lead to development of cell-based regenerative therapy to restore thyroid function

A discovery made by investigators from Beth Israel Deaconess Medical Center and the Boston University School of Medicine may help lead to the development of a cell-based regenerative therapy which could be used to restore thyroid function in patients with cancer who have had their thyroids surgically removed and children born with congenital hypothyroidism.

23 Oct 2015

Biological sensor protein could help combat diabetes, obesity

In the study, researchers showed a protein called NLRP1 is switched on when increased dietary energy (food) intake triggers the cell to become 'unstable'.

23 Oct 2015

University of Arkansas biomedical engineer awarded NIH grant to study chronic wound biomarkers

The National Institutes of Health awarded a University of Arkansas biomedical engineer a new $744,992 grant to improve imaging and early detection of chronic wounds and guide treatments.

22 Oct 2015

Scientists find new way to inhibit growth of lung cancer cells

Scientists have identified a new way to stop the growth of lung cancer cells, by blocking their ability to use alternative sources of nutrition. The discovery was made possible by identifying the metabolic programs used by cancer cells to fuel their growth.

21 Oct 2015

Orange pigment may have potential as anti-cancer drug

An orange pigment found in lichens and rhubarb called parietin may have potential as an anti-cancer drug, scientists at Winship Cancer Institute of Emory University have discovered.

20 Oct 2015

Melatonin and the circadian rhythm: an interview with Professor Kennaway, University of Adelaide

The production of melatonin is controlled by a part of the brain called the suprachiasmatic nucleus (SCN) and its timing fine-tuned by our exposure to light during the morning.

20 Oct 2015

Viking successfully completes safety, tolerability and pharmacokinetic study of VK5211 in elderly subjects

Viking Therapeutics, Inc., a clinical-stage biopharmaceutical company focused on the development of novel, first-in-class or best-in-class therapies for metabolic and endocrine disorders, today announced the successful completion of a short-term safety, tolerability, and pharmacokinetic study of VK5211 in healthy elderly subjects. VK5211, the company's lead program for muscle and bone disorders, is an orally available, non-steroidal selective androgen receptor modulator (SARM) being developed for the treatment of patients recovering from non-elective hip fracture surgery.

20 Oct 2015

Consuming high-fat diet may lead to anxiety and depression, cause measurable changes in the brain

A new study in mice reveals that increased body weight and high blood sugar as a result of consuming a high-fat diet may cause anxiety and depressive symptoms and measurable changes in the brain.

20 Oct 2015

Ember Therapeutics reports initial results from BMP-7 Phase II trial in patients with moderate osteoarthritis of the knee

Ember Therapeutics, Inc., a privately held, New York-based biopharmaceutical company that is developing targeted therapies for osteoarthritis, kidney fibrosis, and other indications using Bone Morphogenetic Protein (BMP)-7, announced today initial results from the Phase II(a) trial of local BMP-7 administration in patients with moderate osteoarthritis of the knee.

20 Oct 2015

Lexicon's telotristat etiprate improves social and physical function, emotional well-being in cancer patients

Lexicon Pharmaceuticals, Inc.'s telotristat etiprate, the first oral therapy in development for the treatment of carcinoid syndrome (CS), was associated with patient-reported improvements in social and physical function and emotional well-being according to new exit interview data from the Phase 3 TELESTAR study presented at the 2015 Neuroendocrine Tumor Society Annual Symposium in Austin, Texas.

19 Oct 2015

LEO Pharma's Enstilar gets FDA approval for topical treatment of plaque psoriasis

LEO Pharma Inc., a wholly owned U.S. subsidiary of LEO Pharma A/S, announced today that Enstilar has been approved by the U.S. Food and Drug Administration for the topical treatment of plaque psoriasis in adults 18 years of age and older.

19 Oct 2015

Study could lead to better understanding of metabolic processes behind type 2 diabetes

Scientists in Sweden have discovered that human intestinal flora regulates the levels of the body's main antioxidant, glutathione, which fights a host of diseases. The findings could lead to new probiotic-delivering foods, and a better understanding of the metabolic processes behind diseases such as type 2 diabetes.

19 Oct 2015

New research shows nicotine increases codeine-induced analgesia

According to new research in rat models, nicotine use over time increases the speed that codeine is converted into morphine within the brain, by increasing the amount of a specific enzyme. It appears smokers' brains are being primed for a bigger buzz from this common pain killer - which could put them at a higher risk for addiction, and possibly even overdose.

19 Oct 2015

Researchers explain how incurable type of blood cancer develops

Researchers in the West Midlands have made a breakthrough in explaining how an incurable type of blood cancer develops from an often symptomless prior blood disorder. The findings could lead to more effective treatments and ways to identify those most at risk of developing the cancer.

18 Oct 2015

WSU scientist wins federal grant to explore metabolism pathways, tobacco carcinogens

A Washington State University researcher has received a $2.6 million federal grant to study the body's ability to keep tobacco smoke components from causing cancer.

16 Oct 2015

New ATA guidelines for managing adult patients with thyroid nodules and DTC published in Thyroid journal

New, evidence-based recommendations from the American Thyroid Association will help guide clinicians in managing patients with thyroid nodules, a common disorder that requires evaluation to distinguish benign nodules from malignancy, interpret biopsy results and molecular marker studies, and initiate risk assessment and cancer screening.

15 Oct 2015

Women with Type 2 diabetes face barrier to physical activity

Women with Type 2 diabetes experience a barrier to physical activity that threatens to make them more sedentary and cause their health to worsen, according to a new study by Amy Huebschmann, MD, MS of the University of Colorado Anschutz Medical Campus.

15 Oct 2015

Metabolism News and Research

Latest Metabolism News and Research

Four microRNAs appear to play critical roles in controlling cholesterol, triglyceride metabolism

Low-weight, high-repetition resistance training increases bone density in adults

Endocannabinoids can affect development of baby's pancreas

Discovery may lead to development of cell-based regenerative therapy to restore thyroid function

Biological sensor protein could help combat diabetes, obesity

University of Arkansas biomedical engineer awarded NIH grant to study chronic wound biomarkers

Scientists find new way to inhibit growth of lung cancer cells

Orange pigment may have potential as anti-cancer drug

Melatonin and the circadian rhythm: an interview with Professor Kennaway, University of Adelaide

Viking successfully completes safety, tolerability and pharmacokinetic study of VK5211 in elderly subjects

Consuming high-fat diet may lead to anxiety and depression, cause measurable changes in the brain

Ember Therapeutics reports initial results from BMP-7 Phase II trial in patients with moderate osteoarthritis of the knee

Lexicon's telotristat etiprate improves social and physical function, emotional well-being in cancer patients

LEO Pharma's Enstilar gets FDA approval for topical treatment of plaque psoriasis

Study could lead to better understanding of metabolic processes behind type 2 diabetes

New research shows nicotine increases codeine-induced analgesia

Researchers explain how incurable type of blood cancer develops

WSU scientist wins federal grant to explore metabolism pathways, tobacco carcinogens

New ATA guidelines for managing adult patients with thyroid nodules and DTC published in Thyroid journal

Women with Type 2 diabetes face barrier to physical activity

Transforming Cardiovascular Care: Insights from Mina Makar at AstraZeneca

Clue's CEO Rhiannon White on the Future of Femtech and PCOS

Freezing Point Osmometry in Life Science Applications