Metabolism News and Research

Latest Metabolism News and Research

Carb breakdown gene linked to obesity, researchers find

Researchers at King's College London and Imperial College London have discovered that people with fewer copies of a gene coding for a carb-digesting enzyme may be at higher risk of obesity. The findings, published in Nature Genetics, suggest that dietary advice may need to be more tailored to an individual's digestive system, based on whether they have the genetic predisposition and necessary enzymes to digest different foods.

31 Mar 2014

New high-risk cancer causing mutation identified for melanoma development

Researchers have discovered that mutations in a specific gene are responsible for a hereditary form of melanoma.

31 Mar 2014

Study links effect of gastric bypass surgery on glucose metabolism and islet function in hypoglycemia patients

University of Cincinnati (UC) researchers have discovered that altered islet cell function and reduced insulin clearance contribute to excessive post-meal insulin response in patients experiencing low blood sugar symptoms (hypoglycemia) following gastric bypass surgery.

29 Mar 2014

Certain inherited DNA sequences may affect prognosis of bladder cancer patients

While patients diagnosed with bladder cancer usually face a favorable prognosis, many experience recurrence after treatment. Because frequent, painful screenings are needed to identify recurrences, the ablility to identify patients at high risk of recurrent cancer could help to improve quality of life for all bladder cancer patients.

29 Mar 2014

UT Southwestern professor honored with 2014 Norman Hackerman Award in Chemical Research

Dr. Benjamin P. Tu, associate professor of biochemistry at UT Southwestern Medical Center, was honored today with the 2014 Norman Hackerman Award in Chemical Research. Dr. Tu was recognized for innovative studies of once-unappreciated molecules that may someday improve treatments for cancer or conditions associated with aging.

28 Mar 2014

Study: Overweight and obese teenagers have higher risk of death before age 50

Although people live longer today than they did 50 years ago, people who were overweight and obese as teenagers aren't experiencing the same gains as other segments of the population, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM).

27 Mar 2014

Retrophin acquires Manchester Pharmaceuticals

Retrophin, Inc. today announced the completion of the previously announced acquisition of Manchester Pharmaceuticals LLC for a total of $62.5 million, including an upfront payment of $29.5 million, plus other payments based on product sales.

27 Mar 2014

Research points strong reason to develop new class of antidepressant drug

Scientists have shown for the first time that a chemical in the brain called galanin is involved in the risk of developing depression.

From The University of Manchester 27 Mar 2014

Small-fruited capsicum contains high concentrations of capsinoids

Researchers have released a new Capsicum annuum pepper germplasm that contains high concentrations of capsinoids.

27 Mar 2014

Genetic testing could help determine drug dosage, reduce side effects

Usually pharmaceutical companies determine the drug dosage just as a mean value. This amount may be too much for patients who absorb the substance faster, and too little for those with a slower metabolism.

27 Mar 2014

Expert highlights the importance of gender-specific approach for treating diabetes mellitus

The international guidelines on the drug-based therapy of diabetes mellitus specify which factors need to be taken into account during treatment.

27 Mar 2014

Mephedrone drug causes acute withdrawal symptoms, shows study

Contrary to popular belief among recreational drug users, mephedrone has several important differences when compared with MDMA, commonly known as ecstasy.

27 Mar 2014

Patients with genetic variants are likely to experience bladder cancer recurrence

In the Western world, bladder cancer is the fourth most common cancer in men and the eighth most common in women, with many patients experiencing recurrence after treatment.

26 Mar 2014

Study lays groundwork for PET imaging studies on human Menkes disease

Scientists at the RIKEN Center for Life Science Technologies have used PET imaging to visualize the distribution in the body of copper, which is deregulated in Menkes disease, a genetic disorder, using a mouse model. This study lays the groundwork for PET imaging studies on human Menkes disease patients to identify new therapy options.

26 Mar 2014

Loyola study finds fewer children at risk of inadequate or deficient vitamin D levels

Under new guidelines from the Institute of Medicine, the estimated number of children who are at risk for having insufficient or deficient levels of vitamin D is drastically reduced from previous estimates, according to a Loyola University Chicago Stritch School of Medicine study.

26 Mar 2014

Study explores dangers of switching from MDMA to mephedrone

Contrary to popular belief among recreational drug users, mephedrone has several important differences when compared with MDMA, commonly known as ecstasy. These differences mean that mephedrone could leave a user with acute withdrawal symptoms and indicate that it may have a higher potential for developing dependence than MDMA according to a study published in British Journal of Pharmacology.

26 Mar 2014

UMass Medical School students win 2014 Harold M. Weintraub Graduate Student Award

Colin Conine and Emma Watson, PhD students in the Graduate School of Biomedical Sciences (GSBS) at the University of Massachusetts Medical School, received the 2014 Harold M. Weintraub Graduate Student Award for research into the mechanisms governing epigenetic inheritance and the complex interactions between diet, gene expression and physiology.

26 Mar 2014

Scientists discover why cerebellar granule cell neurons in A-T patients fail to repair DNA damage

A team of scientists, led by Stuart Lipton, M.D., Ph.D., professor and director of the Neuroscience and Aging Research Center at Sanford-Burnham Medical Research Institute, recently discovered why cerebellar granule cell neurons in patients suffering from ataxia-telangiectasia (A-T) were unable to repair DNA damage and thus died.

26 Mar 2014

Agios initiates AG-120 Phase 1 study to evaluate advanced solid tumors with IDH1 mutation

Agios Pharmaceuticals, Inc., a leader in the fields of cancer metabolism and inborn errors of metabolism, today announced dose administration for the first patient in a Phase 1 study of AG-120 in patients with advanced solid tumors with an isocitrate dehydrogenase-1 (IDH1) mutation.

25 Mar 2014

Diabetes drug reduces amyloid-beta peptides, improves memory in experimental AD models

Researchers from Boston University School of Medicine have found that the diabetic drug, pramlintide, reduces amyloid-beta peptides, a major component of Alzheimer's disease (AD) in the brain and improves learning and memory in two experimental AD models.

25 Mar 2014

Metabolism News and Research

Latest Metabolism News and Research

Carb breakdown gene linked to obesity, researchers find

New high-risk cancer causing mutation identified for melanoma development

Study links effect of gastric bypass surgery on glucose metabolism and islet function in hypoglycemia patients

Certain inherited DNA sequences may affect prognosis of bladder cancer patients

UT Southwestern professor honored with 2014 Norman Hackerman Award in Chemical Research

Study: Overweight and obese teenagers have higher risk of death before age 50

Retrophin acquires Manchester Pharmaceuticals

Research points strong reason to develop new class of antidepressant drug

Small-fruited capsicum contains high concentrations of capsinoids

Genetic testing could help determine drug dosage, reduce side effects

Expert highlights the importance of gender-specific approach for treating diabetes mellitus

Mephedrone drug causes acute withdrawal symptoms, shows study

Patients with genetic variants are likely to experience bladder cancer recurrence

Study lays groundwork for PET imaging studies on human Menkes disease

Loyola study finds fewer children at risk of inadequate or deficient vitamin D levels

Study explores dangers of switching from MDMA to mephedrone

UMass Medical School students win 2014 Harold M. Weintraub Graduate Student Award

Scientists discover why cerebellar granule cell neurons in A-T patients fail to repair DNA damage

Agios initiates AG-120 Phase 1 study to evaluate advanced solid tumors with IDH1 mutation

Diabetes drug reduces amyloid-beta peptides, improves memory in experimental AD models

Clue's CEO Rhiannon White on the Future of Femtech and PCOS

Freezing Point Osmometry in Life Science Applications

Precision in every drop: Inside Hamilton’s syringe technology