Metabolism News and Research

Latest Metabolism News and Research

Findings explain molecular mechanisms underlying microvascular disease in diabetes patients

Patients with diabetes are at increased risk of microvascular complications, which develop when the body's small blood vessels become diseased. One of the most common problems results when wounds fail to heal properly, which can lead to ulcers, chronic infections, and in the most serious cases, limb amputations.

5 Feb 2014

Overweight, obese adults can breathe 7-50% more air per day than adult with healthy weight

Overweight or obese adults can breathe 7-50% more air per day than an adult with healthy weight does, which makes them more vulnerable to air contaminants causing asthma and other pulmonary diseases, according to a study by Dr. Pierre Brochu, a professor at Université de Montréal's School of Public Health.

5 Feb 2014

Edison's vatiquinone receives Orphan Status for treatment of Friedreich's ataxia

Edison Pharmaceuticals today announced that the US Food and Drug Administration has granted Orphan Status to vatiquinone for the treatment of Friedreich's ataxia.

4 Feb 2014

Study shows how pesticides may contribute to development of Parkinson's disease

New research shows how pesticides may increase the risk of Parkinson's disease and that people with certain gene variants may be more susceptible to the disease. The research is published in the February 4, 2014, print issue of Neurology®, the medical journal of the American Academy of Neurology.

4 Feb 2014

Large amounts of choline may be needed to support fetal development during pregnancy

Recent research published in the American Journal of Clinical Nutrition found that during pregnancy, and particularly during the third trimester, large amounts of choline may be needed to support fetal development. Conclusions of the research revealed that current recommendations may be too low. Choline deficiency in pregnant women may result in elevated levels of homocysteine, potentially resulting in birth defects.

31 Jan 2014

Trinidad and Tobago, Johns Hopkins Medicine celebrate achievements of Diabetes Outreach Program

Members of the Trinidad and Tobago Health Science Initiative’s Diabetes Outreach Program joined the country’s Minister of Health Fuad Khan Tuesday in Port of Spain to celebrate the program’s achievements in fighting diabetes in Trinidad and Tobago.

30 Jan 2014

New insight into mammalian circadian rhythms could lead to therapies for metabolic disorders

We've all heard about circadian rhythm, the roughly 24-hour oscillations of biological processes that occur in many living organisms. Yet for all its influence in many aspects of our lives - from sleep to immunity and, particularly, metabolism - relatively little is understood about the mammalian circadian rhythm and the interlocking processes that comprise this complex biological clock.

30 Jan 2014

Biomarker used to diagnose brain injury shows early promise for assessing heart inflammation

A biomarker widely used to diagnose brain injury has shown early promise for assessing the severity of heart inflammation, or myocarditis, find researchers at Columbia University's Mailman School of Public Health, Johns Hopkins, and the Mayo Clinic.

28 Jan 2014

Researchers discover simple blood test that can predict diabetes risk much earlier

An estimated 25.8 million Americans have diabetes. Another 79 million are thought to have "prediabetes," meaning they are at risk of developing type-2 diabetes.

28 Jan 2014

Changes in SirT1 protein can prevent excess metabolic stress associated with obesity, diabetes and aging

Researchers find changes to protein SirT1 can prevent excess metabolic stress associated with obesity, diabetes and aging.

27 Jan 2014

Increased inflammation following infection impairs brain's ability to form spatial memories

Increased inflammation following an infection impairs the brain's ability to form spatial memories - according to new research. The impairment results from a decrease in glucose metabolism in the brain's memory centre, disrupting the neural circuits involved in learning and memory.

25 Jan 2014

Early onset of dietary treatment may slow down progression of Alzheimer's disease

New research findings indicate that an early onset of dietary treatment may slow down the progression of Alzheimer's disease. The study was conducted on mice, and the results will be published in the February issue of Journal of Nutritional Biochemistry. Researchers from the University of Eastern Finland played a key role in the study, which was carried out as part of the LiPiDiDiet project funded by the European Union.

24 Jan 2014

Researchers reveal how genetic susceptibility plays large role in cancer risk

In laboratory experiments conducted on human cell lines at the Johns Hopkins Kimmel Cancer Center, scientists have shown that people carrying certain mutations in two hereditary cancer genes, BRCA2 and PALB2, may have a higher than usual susceptibility to DNA damage caused by a byproduct of alcohol, called acetaldehyde.

24 Jan 2014

Omega-3 fatty acids especially DHA may have even wider range of biological impacts, shows study

A study of the metabolic effects of omega-3 fatty acids, especially DHA, concludes that these compounds may have an even wider range of biological impacts than previously considered, and suggests they could be of significant value in the prevention of fatty liver disease.

24 Jan 2014

Early onset of dietary treatment may slow down progression of Alzheimer's, says research

24 Jan 2014

Cortical thickness may distinguish bipolar from unipolar disorder

Patients with depression have areas of reduced cortical thickness, with clear distinctions between those with bipolar disorder and major depressive disorder, report US researchers.

23 Jan 2014

Regular exposure to mild cold may be a sustainable way to help people lose weight

Regular exposure to mild cold may be a healthy and sustainable way to help people lose weight, according to researchers writing in the Cell Press publication Trends in Endocrinology & Metabolism on January 22nd. On the flip side, that means our warm and cozy homes and offices might be partly responsible for our expanding waistlines.

23 Jan 2014

Function of stem cells in blood-forming system is regulated by estrogen, says study

Scientists have known for years that stem cells in male and female sexual organs are regulated differently by their respective hormones. In a surprising discovery, researchers at the Children's Medical Center Research Institute at UT Southwestern (CRI) and Baylor College of Medicine have found that stem cells in the blood-forming system — which is similar in both sexes — also are regulated differently by hormones, with estrogen proving to be an especially prolific promoter of stem cell self-renewal.

23 Jan 2014

Lack of SIRT1 protein in the liver leads to lower levels of liver FGF21

A new study led by Boston University School of Medicine demonstrates that the abnormal metabolism linked to obesity could be regulated in part by the interaction of two metabolic regulators, called the NAD-dependent deacetylase SIRT1 and fibroblast growth factor 21 (FGF21). Using experimental models, the researchers found that a lack of SIRT1 protein in the liver led to lower levels of a liver secreted protein FGF21, which resulted in an increased likelihood of developing fatty liver disease and obesity.

22 Jan 2014

Strategic placement of care managers in PCMHs can improve outcomes for high-risk diabetes patients

Patient centered medical homes (PCMHs) have been found to be an effective way to help care for patients with chronic diseases such as diabetes. Dr. Robert Gabbay, M.D., Ph.D., FACP, Chief Medical Officer and Senior Vice President at Joslin Diabetes Center, and his team conducted a study that shows the strategic placement of care managers in PCMHs can further improve patient outcomes for high-risk diabetes patients.

22 Jan 2014

Metabolism News and Research

Latest Metabolism News and Research

Findings explain molecular mechanisms underlying microvascular disease in diabetes patients

Overweight, obese adults can breathe 7-50% more air per day than adult with healthy weight

Edison's vatiquinone receives Orphan Status for treatment of Friedreich's ataxia

Study shows how pesticides may contribute to development of Parkinson's disease

Large amounts of choline may be needed to support fetal development during pregnancy

Trinidad and Tobago, Johns Hopkins Medicine celebrate achievements of Diabetes Outreach Program

New insight into mammalian circadian rhythms could lead to therapies for metabolic disorders

Biomarker used to diagnose brain injury shows early promise for assessing heart inflammation

Researchers discover simple blood test that can predict diabetes risk much earlier

Changes in SirT1 protein can prevent excess metabolic stress associated with obesity, diabetes and aging

Increased inflammation following infection impairs brain's ability to form spatial memories

Early onset of dietary treatment may slow down progression of Alzheimer's disease

Researchers reveal how genetic susceptibility plays large role in cancer risk

Omega-3 fatty acids especially DHA may have even wider range of biological impacts, shows study

Early onset of dietary treatment may slow down progression of Alzheimer's, says research

Cortical thickness may distinguish bipolar from unipolar disorder

Regular exposure to mild cold may be a sustainable way to help people lose weight

Function of stem cells in blood-forming system is regulated by estrogen, says study

Lack of SIRT1 protein in the liver leads to lower levels of liver FGF21

Strategic placement of care managers in PCMHs can improve outcomes for high-risk diabetes patients

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