Metabolism News and Research

Latest Metabolism News and Research

Study may open up new ways of approaching metabolic diseases

A study led by the University of Barcelona and the Biomedical Research Networking Center in Diabetes and Associated Metabolic Disorders (CIBERDEM) reveals how a new mechanism could improve the efficiency of currently available treatments for diabetes.

12 Feb 2024

Pregnant women show significant immune system changes linked to gut microbiome

How gut microbiota and metabolite changes relate to immune function during pregnancy.

12 Feb 2024

Rucaparib and its major metabolite exhibit differential biological activity and synergy

Once they enter the body, drugs, apart from carrying out their therapeutic function, are biochemically transformed by the action of the metabolic machinery, a process that facilitates their expulsion.

9 Feb 2024

Higher dietary niacin intake linked to lower COPD risk, study finds

Recent research in Scientific Reports reveals a dose-response relationship between dietary niacin intake and reduced prevalence of chronic obstructive pulmonary disease (COPD), suggesting niacin's potential role in mitigating oxidative stress and inflammation in COPD patients.

8 Feb 2024

Wayne State researchers secure $1.4 million DoD grant for prostate cancer study

A team of researchers from Wayne State University was awarded a $1.4 million, three-year grant from the U.S. Department of Defense for the study, "Cytochrome c acetylation drives prostate cancer aggressiveness and Warburg effect."

7 Feb 2024

AMG 133 (maridebart cafraglutide) weight loss drug shows promise in early trial

AMG 133, an engineered bispecific molecule, demonstrated significant weight loss with a favorable safety profile in a phase 1 clinical trial, offering a promising new treatment option for obesity.

7 Feb 2024

Mitochondria on the move: New discovery could revolutionize treatment of brain diseases

The human brain is an organ that takes nearly from 20 to 25% of the energy the body needs. This high energy demand for neuronal functions depends on the transport and precise distribution of mitochondria — the energy-generating cell organelles — in each neuron.

7 Feb 2024

Gut microbiota alterations may influence immune system changes during pregnancy

During pregnancy, a woman's immune system changes dramatically but researchers don't yet understand all the underlying mechanisms.

7 Feb 2024

New tool can help researchers to better understand the metabolism of microorganisms

Researchers from University of California San Diego, as part of a large collaboration with scientists around the world, have developed a new search tool to help researchers better understand the metabolism of microorganisms.

6 Feb 2024

Patients with non-alcoholic fatty liver disease may benefit from increased dietary niacin intake

Whether higher dietary niacin intake lowers the risk of all-cause, heart and cerebrovascular disease(s).

6 Feb 2024

Paxlovid enhances treatment options for COVID-19 patients

The design, synthesis, and mechanism of action of Paxlovid.

6 Feb 2024

Study links ultra-processed foods to higher metabolic disease risk

Consuming ultra-processed foods (UPFs) is linked to a higher risk of metabolic diseases like obesity and type 2 diabetes mellitus (T2DM), underscoring the need for dietary caution and policy adjustments.

5 Feb 2024

Study unearths sex-dependent blood lipid response to sleep apnea

Sleep apnea, which involves recurring, temporary interruptions of breathing during sleep, can disturb regulation of blood lipid levels, a key factor in the development of cardiovascular disease.

5 Feb 2024

Ramadan fasting linked to favorable metabolic changes and reduced chronic disease risk

Ramadan fasting significantly reduces the risk of lung, colorectal, and breast cancers, showcasing beneficial metabolic changes through a comprehensive metabolomics investigation.

4 Feb 2024

Breakthrough obesity treatments on the horizon, rivaling surgery's success

New obesity pharmacotherapies, including GLP-1 receptor agonists and combinations of entero-pancreatic hormones, show promise in achieving significant weight loss, potentially rivaling bariatric surgery's effectiveness.

4 Feb 2024

Lentils lower cholesterol and sugar response, study finds

Twelve weeks of daily lentil consumption significantly improves fasting cholesterol, postprandial glucose, and inflammation in overweight adults, offering a dietary strategy to enhance metabolic health without gastrointestinal distress.

4 Feb 2024

CAR T cells target senescent cells, improve healthspan in mice

Chimeric antigen receptor (CAR) T cells have transformed the treatment of blood cancers in recent years. And there have been positive signs the "living drugs" can be harnessed against other diseases, like autoimmune disorders.

2 Feb 2024

Scientists discover orderly structure hidden within bacterial biofilms

Bacteria are traditionally imagined as single-cell organisms, spread out sparsely over surfaces or suspended in liquids, but in many environments the true bacterial mode of growth is in sticky clusters called biofilms.

2 Feb 2024

Breakthrough recombinase technology ushers in precise, adaptable gene editing

A team of researchers at the Carl Gustav Carus Faculty of Medicine, TUD Dresden University of Technology, led by Prof. Frank Buchholz, has achieved a major breakthrough in genome editing technology.

1 Feb 2024