Metabolism News and Research

Latest Metabolism News and Research

Folic acid deficiency may be associated with multi-generational impact on health

Folic acid deficiency can cause severe health problems in offspring, including spina bifida, heart defects and placental abnormalities. A study out today reveals that a mutation in a gene necessary for the metabolism of folic acid not only impacts the immediate offspring but can also have detrimental health effects on the next several generations.

27 Sep 2013

Study on tempol impacted gut bacteria may lead to new treatments for obesity

A drug that appears to target specific intestinal bacteria in the guts of mice may create a chain reaction that could eventually lead to new treatments for obesity and diabetes in humans, according to a team of researchers.

25 Sep 2013

Cerebral imaging in patients with early symptoms of AD may have better clinical outcomes

Patients suffering from early symptoms of Alzheimer's disease who were diagnosed sooner than usual using a brain imaging test received Alzheimer-specific medications earlier than those who did not have the brain imaging results available to their doctors or themselves.

25 Sep 2013

Rhythm starts RM-493 clinical trials in obesity patients with genetic deficiency

Rhythm announced today the initiation of the first of a series of clinical trials with RM-493, the company's novel melanocortin 4 receptor (MC4R) agonist, for the treatment of obesity in individuals with a genetic deficiency in the MC4R pathway.

24 Sep 2013

Mayo Clinic expands genomic research by establishing biobank at Arizona campus

Mayo Clinic has again broadened the base of its genomic research efforts by establishing a biobank at its Arizona campus, which will support studies in obesity, metabolism and diabetes, all areas of special concern in the Latino population.

24 Sep 2013

Understanding genetic, physiological basis for metabolic diseases related to circadian function

A new study by a team of University of Notre Dame researchers, which appears in the Sept. 2 edition of the journal PLoS ONE, is a significant step in understanding the molecular genetic and physiological basis for a spectrum of metabolic diseases related to circadian function.

24 Sep 2013

Researchers discover drug that halts growth of brain tumor cells

Working with mice, Johns Hopkins researchers have discovered that weeks of treatment with a repurposed FDA-approved drug halted the growth of - and ultimately left no detectable trace of - brain tumor cells taken from adult human patients.

24 Sep 2013

Humans consuming artificial sweetener are likely to choose high calorie alternatives in future

The results of the new study imply that it is hard to fool the brain by providing it with 'energyless' sweet flavours.

23 Sep 2013

Study shows how lifestyle factors can influence metabolism via resulting alterations in DNA

In the course of life, aging processes, environmental influences and lifestyle factors such as smoking or diet induce biochemical alterations to the DNA. Frequently, these lead to DNA methylation, a process in which methyl groups are added to particular DNA segments, without changing the DNA sequence.

21 Sep 2013

EDCs pose threat to human health, say endocrine experts

In an editorial published in Endocrinology, a journal of The Endocrine Society, endocrine experts agreed that endocrine-disrupting chemicals pose a threat to human health and to the ecosystems of the earth.

20 Sep 2013

New islet transplantation improves results for patients with type 1 diabetes

The latest approach to islet transplantation, in which clusters of insulin-producing cells known as islets are transplanted from a donor pancreas into another person's liver, has produced substantially improved results for patients with type 1 diabetes, and may offer a more durable alternative to a whole pancreas transplant.

20 Sep 2013

SHBG protein indicates risk of type 2 diabetes and metabolic syndrome years in advance

Over the last decade researchers have amassed increasing evidence that relatively low levels of a protein called sex hormone binding globulin (SHBG) can indicate an elevated risk of type 2 diabetes and metabolic syndrome years in advance.

19 Sep 2013

Mayo Clinic receives grant from NIH to support medical research on metabolomics

Mayo Clinic is one of six new federally-funded Comprehensive Metabolomics (met-ah-bol-OH-mics) Centers to support medical research on metabolomics -- the study, at the cellular level, of how molecules are metabolized in the body.

19 Sep 2013

Scientists develop sophisticated assay to track cell growth at low nutrient concentrations

The budding yeast, Saccharomyces cerevisiae, is a prime organism for studying fundamental cellular processes, with the functions of many proteins important in the cell cycle and signaling networks found in human biology having first been discovered in yeast.

18 Sep 2013

Efficacy and safety data on linagliptin and investigational compound empagliflozin* in various diabetes subpopulations presented by Boehringer Ingelheim and Eli Lilly and Company

Boehringer Ingelheim and Eli Lilly and Company today announced they will feature five oral and 12 poster presentations for linagliptin and the investigational compound empagliflozin* at the 49th Annual Meeting of the European Association for the Study of Diabetes (EASD) which will take place in Barcelona, from 23 – 27 September. The presentations will add to the already existing body of data on safety and efficacy of these two compounds.

18 Sep 2013

MR Solutions to release MR/PET and MR/SPECT scanners at WMIC

UK based MR Solutions continues to lead the technology revolution in pre clinical scanning with the launch of the first combined cryogen free, 3T, MR/PET and the first 3T, MR/SPECT scanners at the World Molecular Imaging Conference in Savannah this week (Sept 18-21st).

From MR Solutions 17 Sep 2013

Video demonstrates high throughput screening of cellular bioenergetics of multiple cell lines

INTEGRA has published a video demonstrating how its VIAFLO 96 handheld electronic pipette, used in conjunction with the Seahorse Bioscience XF96 Extracellular Flux Analyzer, provides high throughput screening of the cellular bioenergetics of multiple cell lines.

From INTEGRA Biosciences 17 Sep 2013

Research finding offers new approach to treating melanoma

Scientists at Sanford-Burnham Medical Research Institute today announced the discovery that a gene encoding an enzyme, phosphoinositide-dependent kinase-1, plays an essential role in the development and progression of melanoma. The finding offers a new approach to treating this life-threatening disease.

17 Sep 2013

Oil spill exposure appears to play role in development of hematologic and hepatic toxicity

A new study reports that workers exposed to crude oil and dispersants used during the Gulf oil spill cleanup display significantly altered blood profiles, liver enzymes, and somatic symptoms compared to an unexposed control group.

17 Sep 2013

Researchers identify new link between meal times and daily changes in immune system

A new link between meal times and daily changes in the immune system has been identified by UC San Francisco researchers, and has led them to question assumptions about the roles of specific immune cells in infection and allergy.

17 Sep 2013

Metabolism News and Research

Latest Metabolism News and Research

Folic acid deficiency may be associated with multi-generational impact on health

Study on tempol impacted gut bacteria may lead to new treatments for obesity

Cerebral imaging in patients with early symptoms of AD may have better clinical outcomes

Rhythm starts RM-493 clinical trials in obesity patients with genetic deficiency

Mayo Clinic expands genomic research by establishing biobank at Arizona campus

Understanding genetic, physiological basis for metabolic diseases related to circadian function

Researchers discover drug that halts growth of brain tumor cells

Humans consuming artificial sweetener are likely to choose high calorie alternatives in future

Study shows how lifestyle factors can influence metabolism via resulting alterations in DNA

EDCs pose threat to human health, say endocrine experts

New islet transplantation improves results for patients with type 1 diabetes

SHBG protein indicates risk of type 2 diabetes and metabolic syndrome years in advance

Mayo Clinic receives grant from NIH to support medical research on metabolomics

Scientists develop sophisticated assay to track cell growth at low nutrient concentrations

Efficacy and safety data on linagliptin and investigational compound empagliflozin* in various diabetes subpopulations presented by Boehringer Ingelheim and Eli Lilly and Company

MR Solutions to release MR/PET and MR/SPECT scanners at WMIC

Video demonstrates high throughput screening of cellular bioenergetics of multiple cell lines

Research finding offers new approach to treating melanoma

Oil spill exposure appears to play role in development of hematologic and hepatic toxicity

Researchers identify new link between meal times and daily changes in immune system

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