Metabolism News and Research

Latest Metabolism News and Research

Aflibercept drug shows minor added benefit for overall survival in colorectal cancer patients

The drug aflibercept (trade name: Zaltrap) has been approved in Germany since February 2013 in combination with a certain chemotherapy for adults with metastatic colorectal cancer in whom chemotherapy with oxaliplatin could not stop the disease from progressing.

12 Jul 2013

Research reveals link between elevated BMI and increased risk of gallstone in women

New research reveals a causal association between elevated body mass index (BMI) and increased risk of gallstone disease. Results published in Hepatology, a journal of the American Association for the Study of Liver Diseases, show women are at greater risk of developing gallstones.

12 Jul 2013

Low vitamin D blood levels associated with greater risk of heart disease varies by race, ethnicity

Low vitamin D blood levels are linked to greater risk of heart disease in whites and Chinese, but not in blacks and Hispanics, according to a study appearing this week in JAMA, a journal published by the American Medical Association.

10 Jul 2013

Kessler Foundation scientists receive more than $1.2 M grants from NJ Commission for SCI research

The New Jersey Commission on Spinal Cord Injury Research awarded three grants to scientists at Kessler Foundation. The grants, which exceed $1.2 million, fund studies of assisted walking with Ekso, the impact of aging in the population with spinal cord injury (SCI) and the effects of electrical stimulation on bone loss.

10 Jul 2013

FORMA Therapeutics, CRT partner to discover therapeutic drug candidates against DUBs

FORMA Therapeutics and Cancer Research Technology, Ltd., the commercialization company of Cancer Research UK, announced today a bold research initiative to discover innovative tools, technologies and therapeutic drug candidates against a variety of protein homeostasis regulators called, deubiquitinating enzymes.

9 Jul 2013

Key metabolites in blood could provide clues to long-term overall health and ageing

Scientists have found that key metabolites in blood - chemical 'fingerprints' left behind as a result of early molecular changes before birth or in infancy - could provide clues to a person's long-term overall health and rate of ageing in later life.

9 Jul 2013

Research shows hydrogen sulfide is a key player in colon cancer metabolism

University of Texas Medical Branch at Galveston researchers have discovered that hydrogen sulfide - the pungent-smelling gas produced by rotten eggs - is a key player in colon cancer metabolism, and a potential target for therapies for the disease.

9 Jul 2013

Drugs used to control BP associated with lower risk of heart failure in diabetic patients

Two drugs, telmisartan and valsartan, which are used to reduce blood pressure in people with diabetes, are associated with a lower risk of hospitalization for heart attack, stroke or heart failure, according to a study published in CMAJ (Canadian Medical Association Journal).

9 Jul 2013

Study describes how human mammary gland becomes highly sensitive to insulin during lactation

Why do so many mothers have difficulty making enough milk to breastfeed? A new study by scientists at Cincinnati Children's Hospital Medical Center and the University of California Davis adds to their previous research implicating insulin's role in lactation success.

6 Jul 2013

Mineral element content is low in organic milk compared to conventional milk

Milk from organic farms has a lower concentration of elements like zinc, iodine and selenium than milk produced by conventional farming methods.

5 Jul 2013

Research reveals unconventional production of specialized T cells essential for balanced immune system

New findings from St. Jude Children's Research Hospital reveal an unconventional control mechanism involved in the production of specialized T cells that play a critical role in maintaining immune system balance. The research appears in the current online edition of the scientific journal Nature.

4 Jul 2013

Texas scientists develop new medium for cultivation of beneficial microorganisms

Texas A&M University System scientists from the departments of nutrition and food science and poultry science have developed a new medium for the cultivation of beneficial microorganisms called lactobacilli.

4 Jul 2013

Research shows over 50% of tumors have mutations in p53

Researchers of the Cancer Metabolism group at the Bellvitge Biomedical Research Institute (IDIBELL), Catalan Oncology Institute (ICO) and the Division of Hematology-Oncology of the University of Cincinnati, led by George Thomas, have discovered a role for ribosomal 5S RNA in the formation of a complex that regulates the stability of p53.

4 Jul 2013

Scientists discover network for molecular communication in human embryonic stem cells

Scientists at A*STAR's Genome Institute of Singapore (GIS) and the Max Planck Institute for Molecular Genetics (MPIMG) in Berlin (Germany) have discovered a molecular network in human embryonic stem cells (hESCs) that integrates cell communication signals to keep the cell in its stem cell state.

3 Jul 2013

Activation of brown fat increases heart-related mortality during winter

More people die from heart-disease during the winter months, and according to a new study published in the journal Cell Metabolism, the increase in mortality is possibly due to the accelerated growth of atherosclerotic plaque in the blood vessels caused by the activation of brown fat by the cold.

3 Jul 2013

Researchers find NRF2 signaling plays a role in growth of tumor cells by altering metabolic pathways

Cancer cells have alteration in metabolic pathways as a result of oncogenes that promote tumor growth. NRF2 (nuclear factor erythroid-derived 2-related factor 2) works as a "master gene" that turns on stress response by increasing numerous antioxidants and pollutant-detoxifying genes to protect the lungs from variety of air pollutants such as diesel exhaust and cigarette smoke.

3 Jul 2013

Fondation Leducq grants $6M to cardiovascular scientists to help advance cardiac regeneration therapeutics

The Fondation Leducq in Paris, France, dedicated to improving human health through international efforts to combat cardiovascular disease, awarded a $6 million grant award to a new global research network of cardiovascular scientists which includes three researchers from the Cardiovascular Research Center at Icahn School of Medicine at Mount Sinai.

2 Jul 2013

Father's lifestyle has potential to affect DNA of multiple generations

Gene mutations caused by a father's lifestyle can be inherited by his children, even if those mutations occurred before conception. What's more, these findings show that mutations in the germ-line are present in all cells of the children, including their own germ cells. This means that a father's lifestyle has the potential to affect the DNA of multiple generations and not just his immediate offspring. These findings were published in the July 2013 issue of The FASEB Journal.

2 Jul 2013

Pathway Genomics collaborates with Singapore-based company, Parkway Laboratory Services

Pathway Genomics Corporation, a San Diego-based clinical laboratory that offers genetic testing services internationally, has partnered with Parkway Laboratory Services Ltd, an ancillary service of Parkway Pantai Limited, the largest private healthcare provider in Singapore, and one of the largest private healthcare providers in Asia.

1 Jul 2013

Nano and laser technology packed into small device tests antibiotic treatment in minutes

Researchers at EPFL have built a matchbox-sized device that can test for the presence of bacteria in a couple of minutes, instead of up to several weeks. A nano-lever vibrates in the presence of bacterial activity, while a laser reads the vibration and translates it into an electrical signal that can be easily read-the absence of a signal signifies the absence of bacteria.

1 Jul 2013

Metabolism News and Research

Latest Metabolism News and Research

Aflibercept drug shows minor added benefit for overall survival in colorectal cancer patients

Research reveals link between elevated BMI and increased risk of gallstone in women

Low vitamin D blood levels associated with greater risk of heart disease varies by race, ethnicity

Kessler Foundation scientists receive more than $1.2 M grants from NJ Commission for SCI research

FORMA Therapeutics, CRT partner to discover therapeutic drug candidates against DUBs

Key metabolites in blood could provide clues to long-term overall health and ageing

Research shows hydrogen sulfide is a key player in colon cancer metabolism

Drugs used to control BP associated with lower risk of heart failure in diabetic patients

Study describes how human mammary gland becomes highly sensitive to insulin during lactation

Mineral element content is low in organic milk compared to conventional milk

Research reveals unconventional production of specialized T cells essential for balanced immune system

Texas scientists develop new medium for cultivation of beneficial microorganisms

Research shows over 50% of tumors have mutations in p53

Scientists discover network for molecular communication in human embryonic stem cells

Activation of brown fat increases heart-related mortality during winter

Researchers find NRF2 signaling plays a role in growth of tumor cells by altering metabolic pathways

Fondation Leducq grants $6M to cardiovascular scientists to help advance cardiac regeneration therapeutics

Father's lifestyle has potential to affect DNA of multiple generations

Pathway Genomics collaborates with Singapore-based company, Parkway Laboratory Services

Nano and laser technology packed into small device tests antibiotic treatment in minutes

Clue's CEO Rhiannon White on the Future of Femtech and PCOS

Freezing Point Osmometry in Life Science Applications

Precision in every drop: Inside Hamilton’s syringe technology