Metabolism News and Research

Latest Metabolism News and Research

Positive results from Edison’s EPI-743 phase 2A study on Leigh Syndrome

Edison Pharmaceuticals today announced positive results of a recently completed phase 2A study entitled, "Prospective Open Label Study of EPI-743 in Children with Leigh Syndrome (Subacute Necrotizing Encephalomyelopathy)."

13 Sep 2012

Some gut microbes increase absorption of dietary fats

You may think you have dinner all to yourself, but you're actually sharing it with a vast community of microbes waiting within your digestive tract. A new study from a team including Carnegie's Steve Farber and Juliana Carten reveals that some gut microbes increase the absorption of dietary fats, allowing the host organism to extract more calories from the same amount of food.

13 Sep 2012

Scheduled high-fat diet can reset circadian metabolism and reduce body weight

New research from the Hebrew University of Jerusalem shows that a carefully scheduled high-fat diet can lead to a reduction in body weight and a unique metabolism in which ingested fats are not stored, but rather used for energy at times when no food is available.

13 Sep 2012

Latinos more likely to store fat in the pancreas and develop type 2 diabetes

Latinos are more likely to store fat in the pancreas and are less able to compensate by excreting additional insulin, a Cedars-Sinai study shows.

12 Sep 2012

'Deep sleep' intimately involved in complex control of pubertal onset

Slow-wave sleep, or 'deep sleep', is intimately involved in the complex control of the onset of puberty, according to a recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology and Metabolism (JCEM).

12 Sep 2012

Genes predict the brain's reaction to smoking

Have you ever wondered why some people find it so much easier to stop smoking than others? New research shows that vulnerability to smoking addiction is shaped by our genes. A study from the Montreal Neurological Institute and Hospital - The Neuro, McGill University shows that people with genetically fast nicotine metabolism have a significantly greater brain response to smoking cues than those with slow nicotine metabolism.

12 Sep 2012

Karolinska Institutet professor receives Fernström Foundation Nordic Prize for obesity research

This year's Fernström Foundation Nordic Prize, worth SEK 1 million, goes to Professor Peter Arner from Karolinska Institutet, Sweden, who conducts research on fat. His team was the first to show that fat cells are formed throughout one's lifetime, not just in childhood.

11 Sep 2012

Half of all people of South Asian, African descent will develop diabetes by age 80

Half of all people of South Asian, African and African Caribbean descent will develop diabetes by age 80 according to a new study published today. The study is the first to reveal the full extent of ethnic differences in the risk of developing type 2 diabetes and also provides some answers as to the causes of the increased risk.

11 Sep 2012

U of I microbial engineer synthesizes 2-fucosyllactose to protect babies from pathogens

A University of Illinois microbial engineer has synthesized a sugar in human milk that is thought to protect babies from pathogens. That's important because 2FL, the shorthand scientists use to describe this human milk oligosaccharide (HMO), has not been added to infant formula because HMOs are incredibly expensive.

11 Sep 2012

Exercise, good nutrition play a crucial role in maintaining health and fighting disease

A new study just published in the journal Applied Physiology, Nutrition, and Metabolism (APNM) reaffirms the crucial role exercise along with good nutrition play in maintaining health and fighting disease.

11 Sep 2012

Study discovers pathways that govern instability of GAA/TTC repeats

A study of more than 6,000 genes in a common species of yeast has identified the pathways that govern the instability of GAA/TTC repeats. In humans, the expansions of these repeats is known to inactivate a gene - FXN - which leads to Friedreich's ataxia, a neurodegenerative disease that is currently incurable. In yeast, long repeats also destabilize the genome, manifested by the breakage of chromosomes.

11 Sep 2012

Researchers gain new insight into regulation of adult nerve cell generation in the hypothalamus

Researchers from the University of Utah have gained new insight into the regulation of adult nerve cell generation in the hypothalamus, the part of the brain that regulates many aspects of behavior, mood, and metabolism.

11 Sep 2012

Endocrine Society issues practice guideline for diagnosis and treatment of hypertriglyceridemia

The Endocrine Society today issued a Clinical Practice Guideline (CPG) for the diagnosis and treatment of hypertriglyceridemia. Triglycerides are a type of fat found in the blood and are associated with cardiovascular risk. The CPG, entitled "Evaluation and Treatment of Hypertriglyceridemia: An Endocrine Society Clinical Practice Guideline" appears in the September 2012 issue of the Journal of Clinical Endocrinology and Metabolism (JCEM), a publication of The Endocrine Society.

10 Sep 2012

BCAA supplementation may treat autism and/or epilepsy

An international team of researchers, led by scientists at the University of California, San Diego and Yale University schools of medicine, have identified a form of autism with epilepsy that may potentially be treatable with a common nutritional supplement.

7 Sep 2012

Study sheds light on how high-fibre diet affects the gut environment

Savvy consumers and health professionals know that fibre is an essential nutrient associated with important health benefits, yet barriers such as overall poor tolerance to higher-fibre diets may be why average intake is far less than experts recommend.

7 Sep 2012

Study investigates effects of acidity on breast and pancreatic cancer cell lines

Researchers at Moffitt Cancer Center and colleagues at the University of South Florida and Wayne State University have discovered that tumor cell survival relies on adaptation to acidic conditions in the tumor microenvironment.

7 Sep 2012

New findings establish connection between microRNAs and cellular metabolism

New findings establish a connection between microRNAs and cellular metabolism, suggesting that a drug designed to inhibit these tiny molecules -- once considered to be "junk" DNA -- would have a positive effect against obesity.

7 Sep 2012

Eliminating jnk3 enzyme leads to 90% reduction in Alzheimer's plaque-forming compounds

Scientists have found that eliminating an enzyme from mice with symptoms of Alzheimer's disease leads to a 90 percent reduction in the compounds responsible for formation of the plaques linked to Alzheimer's disease.

6 Sep 2012

Study sheds light on why women gain fat following menopause

A high-fat diet triggers chemical reactions in female mice that could explain why women are more likely than men to gain fat in the abdomen after eating excess saturated fat, new research suggests. The study also sheds light on why women gain fat following menopause.

6 Sep 2012

Researchers identify HIF2α gene mutation in cancer tumor cells

For the first time, a mutation in HIF2α, a specific group of genes known as transcription factors that is involved in red blood cell production and cell metabolism, has been identified in cancer tumor cells.

6 Sep 2012

Metabolism News and Research

Latest Metabolism News and Research

Positive results from Edison’s EPI-743 phase 2A study on Leigh Syndrome

Some gut microbes increase absorption of dietary fats

Scheduled high-fat diet can reset circadian metabolism and reduce body weight

Latinos more likely to store fat in the pancreas and develop type 2 diabetes

'Deep sleep' intimately involved in complex control of pubertal onset

Genes predict the brain's reaction to smoking

Karolinska Institutet professor receives Fernström Foundation Nordic Prize for obesity research

Half of all people of South Asian, African descent will develop diabetes by age 80

U of I microbial engineer synthesizes 2-fucosyllactose to protect babies from pathogens

Exercise, good nutrition play a crucial role in maintaining health and fighting disease

Study discovers pathways that govern instability of GAA/TTC repeats

Researchers gain new insight into regulation of adult nerve cell generation in the hypothalamus

Endocrine Society issues practice guideline for diagnosis and treatment of hypertriglyceridemia

BCAA supplementation may treat autism and/or epilepsy

Study sheds light on how high-fibre diet affects the gut environment

Study investigates effects of acidity on breast and pancreatic cancer cell lines

New findings establish connection between microRNAs and cellular metabolism

Eliminating jnk3 enzyme leads to 90% reduction in Alzheimer's plaque-forming compounds

Study sheds light on why women gain fat following menopause

Researchers identify HIF2α gene mutation in cancer tumor cells

Clue's CEO Rhiannon White on the Future of Femtech and PCOS

Freezing Point Osmometry in Life Science Applications

Precision in every drop: Inside Hamilton’s syringe technology