Metabolism News and Research

Latest Metabolism News and Research

Promising implications for improving cellular immunotherapy for treatment of cancer

New research from the Trudeau Institute laboratory of Dr. Edward L. Pearce (Washington University) has promising implications for improving a treatment for cancer known as cellular immunotherapy. The findings were just published in the The Journal of Immunology.

30 Jul 2012

New drug can aid in losing weight and keeping it off

A new drug could aid in losing weight and keeping it off. The drug, described in the journal Cell Metabolism on July 26, increases sensitivity to the hormone leptin, a natural appetite suppressant found in the body. Although so far the new drug has only been tested on mice, the findings have implications for the development of new treatments for obesity in humans.

28 Jul 2012

Potential biomarker to predict lung cancer patients' response to chemotherapy

Patients with the most common type of lung cancer are notoriously insensitive to chemotherapy drugs, including cisplatin. New findings related to the cellular pathways that regulate responses to cisplatin have now been published by Cell Press on July 26th in the journal Cell Reports.

27 Jul 2012

Novel method of identifying molecules that can help prevent diabetes

Pancreatic beta cells produce insulin, responsible for controlling blood sugar levels and thus essential for our survival. Among the numerous factors that affect the workings of these cells, a protein called Cx36 was identified a few months ago by a research team at the UNIGE.

27 Jul 2012

Anakinra can dramatically limit amount of brain damage in stroke patients

Scientists led by the President of The University of Manchester have demonstrated a drug which can dramatically limit the amount of brain damage in stroke patients.

From The University of Manchester 27 Jul 2012

LPL deficiency treatment poised to be first gene therapy in Europe

For the first time, the European Medicines Agency has recommended gene therapy for approval in Europe.

26 Jul 2012

Fatty acids normalize without help in girls with eating disorders

Omega-3 essential fatty acid supplementation is unnecessary for adolescent girls with eating disorders and weight-loss eating disorder, as levels normalize once they return to normal weight, say researchers.

26 Jul 2012

Roche Diabetes Care announces availability of new ACCU-CHEK Nano SmartView System

Roche Diabetes Care, makers of ACCU-CHEK products and services, is pleased to announce the availability of the new, user-friendly ACCU-CHEK Nano SmartView System.

26 Jul 2012

WASC accredits Cedars-Sinai PhD program in biomedical sciences and translational medicine

The Graduate Program in Biomedical Sciences and Translational Medicine at Cedars-Sinai has been accredited by the Western Association of Schools and Colleges, an affirmation that the PhD-awarding educational effort meets the most rigorous standards of higher learning.

25 Jul 2012

Roche now offers expanded portfolio of blood screening solutions

Roche announced today that it now offers an expanded portfolio of blood screening solutions with an integrated serology testing offering.

25 Jul 2012

EC grants Marketing Authorisation to Boehringer Ingelheim and Lilly’s Jentadueto for diabetes

Boehringer Ingelheim and Eli Lilly and Company received Marketing Authorisation from the European Commission for Jentadueto which combines the DPP-4 inhibitor, linagliptin and metformin in a single tablet.

25 Jul 2012

Vanderbilt researchers receives new $2.1M grant to develop microbrain bioreactor

Take a millionth of a human brain and squeeze it into a special chamber the size of a mustard seed. Link it to a second chamber filled with cerebral spinal fluid and thread both of them with artificial blood vessels in order to create a microenvironment that makes the neurons and other brain cells behave as if they were in a living brain. Then surround the chambers with a battery of sensors that monitor how the cells respond when exposed to minute quantities of dietary toxins, disease organisms or new drugs under development.

25 Jul 2012

Favorable results from BioCryst’s ulodesine plus allopurinol Phase 2b trial on gout

BioCryst Pharmaceuticals, Inc. announced favorable 52-week safety results and sustained efficacy from the extension phase of its randomized Phase 2b trial of ulodesine (BCX4208) added to allopurinol in patients with gout who had failed to reach the serum uric acid (sUA) therapeutic goal of <6 mg/dL on allopurinol alone, as well as positive Phase 2 safety results in patients with mild to moderate renal impairment.

25 Jul 2012

BD youth show altered frontal lobe bioenergetic metabolism

Results from a US study suggest that depressed unmedicated adolescents with bipolar disorder (BD) have altered frontal lobe mitochondrial function.

24 Jul 2012

Pancreatic cancer risk may be lowered by high dietary antioxidant intake

Increasing dietary intake of the antioxidant vitamins C, E, and selenium could help cut the risk of developing pancreatic cancer by up to two thirds, suggests research published online in the journal Gut.

24 Jul 2012

Berg Pharma initiates BPM 31543 clinical trial for chemotherapy-induced alopecia

Berg Pharma, a Boston-based pharmaceutical company focused on discovery and development of new treatments in cancer and metabolic diseases, announced the initiation of a clinical trial entitled "Phase I Dose-Escalation Study to Evaluate the Safety, Tolerability and Pharmacokinetics of a Topical Compound 31543 in Adult Patients Receiving Chemotherapy for the Treatment of Breast Cancer."

23 Jul 2012

Protein associated with Huntington’s and other neurodegenerative diseases has several brain-specific forms

A protein essential for metabolism and recently associated with neurodegenerative diseases also occurs in several brain-specific forms. This discovery emerged in the course of a research project funded by the Austrian Science Fund FWF, the findings of which have now been published in the journal Human Molecular Genetics.

23 Jul 2012

CHD risk needs separating by glycemic status

People with diabetes not only have a higher incidence of coronary heart disease events compared with people without diabetes, but they differ in the type of risk factors they have for such events, report US researchers.

23 Jul 2012

Targeting monocyte activation may reduce arterial inflammation in HIV-infected patients

The elevated risk of cardiovascular disease seen in patients infected with HIV appears to be associated with increased inflammation within the arteries, according to a study that will appear in a special issue of JAMA published in conjunction with the International AIDS Conference.

23 Jul 2012

Study identifies genetic markers that influence protein involved in regulating oestrogen, testosterone levels

A research study led by the Peninsula College of Medicine and Dentistry, University of Exeter, and Boston University School of Medicine, in collaboration with a global consortium, has identified genetic markers that influence a protein involved in regulating oestrogen and testosterone levels in the bloodstream.

21 Jul 2012

Metabolism News and Research

Latest Metabolism News and Research

Promising implications for improving cellular immunotherapy for treatment of cancer

New drug can aid in losing weight and keeping it off

Potential biomarker to predict lung cancer patients' response to chemotherapy

Novel method of identifying molecules that can help prevent diabetes

Anakinra can dramatically limit amount of brain damage in stroke patients

LPL deficiency treatment poised to be first gene therapy in Europe

Fatty acids normalize without help in girls with eating disorders

Roche Diabetes Care announces availability of new ACCU-CHEK Nano SmartView System

WASC accredits Cedars-Sinai PhD program in biomedical sciences and translational medicine

Roche now offers expanded portfolio of blood screening solutions

EC grants Marketing Authorisation to Boehringer Ingelheim and Lilly’s Jentadueto for diabetes

Vanderbilt researchers receives new $2.1M grant to develop microbrain bioreactor

Favorable results from BioCryst’s ulodesine plus allopurinol Phase 2b trial on gout

BD youth show altered frontal lobe bioenergetic metabolism

Pancreatic cancer risk may be lowered by high dietary antioxidant intake

Berg Pharma initiates BPM 31543 clinical trial for chemotherapy-induced alopecia

Protein associated with Huntington’s and other neurodegenerative diseases has several brain-specific forms

CHD risk needs separating by glycemic status

Targeting monocyte activation may reduce arterial inflammation in HIV-infected patients

Study identifies genetic markers that influence protein involved in regulating oestrogen, testosterone levels

Clue's CEO Rhiannon White on the Future of Femtech and PCOS

Freezing Point Osmometry in Life Science Applications

Precision in every drop: Inside Hamilton’s syringe technology