Metabolism News and Research

Latest Metabolism News and Research

PNAS publishes Roche manuscript on generation of human bispecific IgG antibodies

The Roche manuscript: "Immunoglobulin Domain Crossover as a Generic Approach for the Production of Bispecific IgG Antibodies" has been published in the prestigious Proceedings of the National Academy of Sciences of the USA.

23 Jun 2011

Adding leucine to diets improves insulin sensitivity, pre-diabetic condition and metabolic syndrome

A study led by researchers at the Joslin Diabetes Center suggests that adding the amino acid leucine to their diets may help those with pre-diabetes or metabolic syndrome.

23 Jun 2011

Endocrine Practice journal publishes new clinical guidelines on hyperthyroidism

New clinical guidelines for optimal care of patients with hyperthyroidism, a condition when the thyroid gland produces more thyroid hormone than the body needs, which affects about one percent of Americans, appear in the current issue of Endocrine Practice, the journal of the American Association of Clinical Endocrinologists.

22 Jun 2011

Nine young clinical investigators earn recognition from Damon Runyon Cancer Research Foundation

The Damon Runyon Cancer Research Foundation named five new Damon Runyon Clinical Investigators at its spring 2011 Clinical Investigator Award Committee review.

22 Jun 2011

Disease-modifying antirheumatic drugs reduce risk of diabetes from RA, psoriasis

In a study that included nearly 14,000 patients with rheumatoid arthritis or psoriasis, the use of certain disease-modifying antirheumatic drugs was found to lower the risk of diabetes, according to a study in the June 22/29 issue of JAMA.

22 Jun 2011

EC grants marketing authorization to BYDUREON for treatment of type 2 diabetes

Eli Lilly and Company, together with Amylin Pharmaceuticals, Inc. and Alkermes, Inc., announced today that the European Commission has granted marketing authorization to BYDUREON.

21 Jun 2011

Lorcaserin Phase 3 trial data on type 2 diabetes to be presented at ADA 2011

Arena Pharmaceuticals, Inc. and Eisai Inc. announced today that lorcaserin data from the Phase 3 BLOOM-DM trial will be presented in poster sessions at the American Diabetes Association's (ADA) 71st Scientific Sessions in San Diego, California.

21 Jun 2011

Amylin to present data on investigational diabetes drug candidates at ADA annual meeting

Amylin Pharmaceuticals, Inc. today announced that the Company will present data for its two first-in-class diabetes drugs, BYETTA injection and SYMLIN injection, and its investigational diabetes drug candidates BYDUREON and exenatide once monthly at the 71st Scientific Sessions of the American Diabetes Association (ADA) being held in San Diego, CA from June 24 to June 28.

21 Jun 2011

Novel biomarker-development pipeline approach for human diseases

Researchers at Fred Hutchinson Cancer Research Center have demonstrated in mice that the performance of a novel biomarker-development pipeline using targeted mass spectrometry is robust enough to support the use of an analogous approach in humans.

20 Jun 2011

Scientists discover linchpin protein that drives mitochondria's calcium machinery

Mitochondria, those battery-pack organelles that fuel the energy of almost every living cell, have an insatiable appetite for calcium. Whether in a dish or a living organism, the mitochondria of most organisms eagerly absorb this chemical compound.

20 Jun 2011

Genomic study identifies MCU that regulates calcium transport into mitochondria

Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, and collaborators at Massachusetts General Hospital (MGH), the Broad Institute, and the David H. Koch Institute for Integrative Cancer Research at the Massachusetts Institute of Technology (MIT), today announced new findings published in Nature.

20 Jun 2011

Short warm-ups permit greater cycling performance

Coaches, physiologists and athletes alike will attest to the importance of warming up before athletic competition. Warming up increases muscle temperature, accelerates oxygen uptake kinetics and increases anaerobic metabolism, all of which enhance performance.

18 Jun 2011

$Future burden of fractures could be avoided with increased treatment uptake: Study$

Future burden of fractures could be avoided with increased treatment uptake: Study

It pays to prevent fractures. That's one of the main findings of a landmark report 'Osteoporosis - Burden, Healthcare provision and Opportunities in the European Union' newly published in the journal Archives of Osteoporosis.

18 Jun 2011

Roche RTCA HT Instrument allows fully-automated impedance screens for GPCRs

Label-free technologies have entered the stage of cellular drug discovery and high-throughput screening (HTS). For the measurement of G protein-coupled receptor (GPCR) activation electrical impedance represents an excellent universal readout technology, since different signaling pathways can be measured in one assay format using recombinant as well as primary cells.

17 Jun 2011

Medical societies urge diabetes patients to remain on their prescribed medications

Diabetes leaders today are responding to the announcement made by the U.S. Food and Drug Administration (FDA) yesterday that the use of the diabetes medication Actos (pioglitazone) for more than one year may be associated with an increased risk of bladder cancer.

17 Jun 2011

Snack-based diet can increase risk of obesity

A high-fat diet can be bad for your health. However, a snack-based "cafeteria"-style diet of highly palatable, energy-dense foods is even worse, according to new research.

17 Jun 2011

Children born pre-term have persistent drive to succeed

In the longest running U.S. study of premature infants who are now 23 years old, University of Rhode Island Professor of Nursing Mary C. Sullivan has found that premature infants are less healthy, have more social and school struggles and face a greater risk of heart-health problems in adulthood.

16 Jun 2011

Magnesium essential for absorption and metabolism of vitamin D and calcium

Magnesium deficiency is an important factor in the results obtained from vitamin D. According to Dr. Carolyn Dean, MD, ND, magnesium expert and Medical Director of the nonprofit Nutritional Magnesium Association, the effectiveness and benefits of vitamin D are greatly undermined in the absence of adequate levels of magnesium in the body.

15 Jun 2011

High FGF-23 hormone levels linked to increased risk of end-stage renal disease and death

Patients in the early stages of chronic kidney disease who had elevated levels of the endocrine hormone fibroblast growth factor 23 (that regulates phosphorus metabolism) had an associated increased risk of end-stage renal disease and death, according to a study in the June 15 issue of JAMA.

15 Jun 2011

Research reveals how humans of different ancestry process polyunsaturated fat

Over the past decade, much progress has been made regarding the understanding and promise of personalized medicine. Scientists are just beginning to consider the impact of gene-diet interactions in different populations in regards to disease prevention and treatment.

15 Jun 2011

Metabolism News and Research

Latest Metabolism News and Research

PNAS publishes Roche manuscript on generation of human bispecific IgG antibodies

Adding leucine to diets improves insulin sensitivity, pre-diabetic condition and metabolic syndrome

Endocrine Practice journal publishes new clinical guidelines on hyperthyroidism

Nine young clinical investigators earn recognition from Damon Runyon Cancer Research Foundation

Disease-modifying antirheumatic drugs reduce risk of diabetes from RA, psoriasis

EC grants marketing authorization to BYDUREON for treatment of type 2 diabetes

Lorcaserin Phase 3 trial data on type 2 diabetes to be presented at ADA 2011

Amylin to present data on investigational diabetes drug candidates at ADA annual meeting

Novel biomarker-development pipeline approach for human diseases

Scientists discover linchpin protein that drives mitochondria's calcium machinery

Genomic study identifies MCU that regulates calcium transport into mitochondria

Short warm-ups permit greater cycling performance

Future burden of fractures could be avoided with increased treatment uptake: Study

Roche RTCA HT Instrument allows fully-automated impedance screens for GPCRs

Medical societies urge diabetes patients to remain on their prescribed medications

Snack-based diet can increase risk of obesity

Children born pre-term have persistent drive to succeed

Magnesium essential for absorption and metabolism of vitamin D and calcium

High FGF-23 hormone levels linked to increased risk of end-stage renal disease and death

Research reveals how humans of different ancestry process polyunsaturated fat

Clue's CEO Rhiannon White on the Future of Femtech and PCOS

Freezing Point Osmometry in Life Science Applications

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