Metabolism News and Research

Latest Metabolism News and Research

Good quality sleep is essential for overall health

Sleep plays a critical role in immune function, metabolism, memory, learning, growth, stress reduction and other vital functions. So getting the right amount of good quality sleep is as essential for overall health as good nutrition and regular exercise.

30 Sep 2011

Lin28/let-7 pathway plays an unexpected key role in type 2 diabetes

A pathway activated in cancer plays an unexpected key role in metabolic diseases like type 2 diabetes, according to a study by researchers at Children's Hospital Boston. Evidence that the Lin28/let-7 pathway influences the cellular response to glucose provides a unifying theme to perplexing data that associates human genetic variation with diabetes risk.

30 Sep 2011

Intensive blood glucose control therapy provides no added benefit against cognitive decline in older diabetics

Intensive control of blood sugar levels beyond standard targets provides no additional protection against cognitive decline in older people with diabetes than standard treatment, according to a national study coordinated by researchers at Wake Forest Baptist Medical Center.

29 Sep 2011

FOX06 protein contributes to liver overproduction of glucose in diabetes

Researchers at the John G. Rangos Sr. Research Center at Children's Hospital of Pittsburgh of UPMC and the University of Pittsburgh School of Medicine have identified a powerful molecular pathway that regulates the liver's management of insulin and new glucose production, which could lead to new therapies for diabetes.

29 Sep 2011

Roche to sponsor 3rd Annual World MRSA Day

As part of its ongoing work in the prevention and control of serious infections in healthcare settings, Roche announced today its sponsorship of the 3rd Annual World MRSA Day.

From Roche Sequencing and Life Science 29 Sep 2011

NIH-funded project to study risk factors for alcoholism in Native Americans

Scripps Research Institute Professor Cindy Ehlers has been awarded a prestigious $3.6 million MERIT Award grant by the National Institutes of Health (NIH) to study the risk factors for alcoholism in Native Americans.

28 Sep 2011

Takeda, AACE partner to launch Diabetes Navigator website

The American Association of Clinical Endocrinologists (AACE) and Takeda Pharmaceuticals North America Inc. (Takeda) have partnered to launch the Diabetes Navigator, a compendium capturing a selection of useful and reliable type 2 diabetes information available online for patients and caregivers.

28 Sep 2011

Liver transplantation candidates without HCC derive greater survival benefit from LDLT

New research shows liver transplantation candidates without hepatocellular carcinoma (HCC) derive a greater survival benefit from a living donor liver transplant (LDLT) than waiting for a deceased donor liver transplant.

28 Sep 2011

Tips for health-conscious college students

If you polled students at any college or university, chances are one of their top complaints would be connected to diet. Everyone's heard of the "Freshman 15," and even when students are trying to eat well, it can be a challenge when time-intensive studies—and a thriving social life—translate into less-than-ideal food choices.

28 Sep 2011

Asians struggling with alcoholism may benefit from naltrexone

New UCLA psychology research indicates that Asians who are struggling with alcoholism may benefit especially from naltrexone, one of three medications approved by the U.S. Food and Drug Administration for the treatment of alcoholism.

28 Sep 2011

Scientists identify proteasome phosphatase that appears to regulate removal of damaged proteins

A study by scientists at the University of California, San Diego and UC Irvine has identified an enzyme called a proteasome phosphatase that appears to regulate removal of damaged proteins from a cell. The understanding of how this process works could have important implications for numerous diseases, including cancer and Parkinson's disease.

28 Sep 2011

Alnylam commences ALN-PCS Phase I trial in severe hypercholesterolemia

Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, announced today that it has initiated dosing in its Phase I clinical trial with ALN-PCS, an RNAi therapeutic targeting proprotein convertase subtilisin/kexin type 9, or PCSK9, for the treatment of severe hypercholesterolemia.

27 Sep 2011

New insights into actions of NSAIDs

Ibuprofen, naproxen, and related non-steroidal anti-inflammatory drugs (NSAIDs) - the subjects of years of study - still have some secrets to reveal about how they work.

26 Sep 2011

Scientists reveal link between lipid cell dysfunction and metabolic diseases

By measuring the radioactive isotope carbon-14, scientists at Karolinska Institutet have revealed an association between lipid cell dysfunction and diseases such as obesity, diabetes and blood lipid disorders.

26 Sep 2011

Afinitor Phase III study on angiomyolipomas associated with TSC meets primary endpoint

A Phase III study of Afinitor (everolimus) tablets in patients with non-cancerous kidney tumors, or angiomyolipomas, associated with tuberous sclerosis complex (TSC) met its primary endpoint of best overall angiomyolipoma response rate, which includes reduction in kidney tumor size and absence of new tumors.

26 Sep 2011

Combination of Afinitor, exemestane reduces risk of breast cancer progression in women

A pivotal Phase III study shows Afinitor (everolimus) tablets plus exemestane, a hormonal therapy, more than doubled the time women lived without tumor growth (progression-free survival; PFS) and significantly reduced the risk of cancer progression by 57% versus exemestane alone in patients with advanced breast cancer.

26 Sep 2011

Drug combo for breast cancer in post-menopausal women shows promise

Combining two drugs in post-menopausal women with a certain type of advanced breast cancer more than doubled the time they lived without their disease getting worse, a new study data showed.

26 Sep 2011

Researchers discover 16 genes linked with breast cancer prognosis

Researchers at Wake Forest Baptist Medical Center have made a discovery that brings them one step closer to being able to better predict which patients have the best chance of surviving breast cancer.

26 Sep 2011

BPA may not affect male testes

Bisphenol A (BPA), a common component of plastic used in many consumer products, has recently become infamous -- and banned in some places -- because it can mimic natural estrogen in the body. A new study by Brown University toxicologists, however, finds that male mice whose mothers were exposed even to high doses of BPA while pregnant developed no signs of harm to their testes as adults.

23 Sep 2011

Anti-obesity drug Contrave may get another chance to prove itself

With rise obesity around the world there should have been a number of drugs to combat it. The reality is different. There are no safe and effective drugs in the market at present.

22 Sep 2011