Metabolism News and Research

Latest Metabolism News and Research

Unraveling the immune system's response to nanoparticle drug delivery

To reduce the side effects associated with chemotherapy treatments, researchers have investigated the use of delivery systems that can take more drugs directly to the tumor. Ninh (Irene) La-Beck, Pharm.D., from the Department of Immunotherapeutics and Biotechnology at the Texas Tech University Health Sciences Center (TTUHSC) Jerry H. Hodge School of Pharmacy is one of those researchers.

17 Nov 2023

Ketogenic diets and diabetes: A promising match or a questionable pair?

A recent research article in "Diabetes Therapy" examines the effectiveness of ketogenic diets in managing Type 1, Type 2, and gestational diabetes. Despite potential benefits like weight loss and improved glycemic control, the study highlights unresolved issues and the need for more extensive research before incorporating ketogenic diets into clinical guidelines for diabetes management.

16 Nov 2023

Scientists uncover "genomic tug of war" that influences chemotherapy's effectiveness

Some patients with myelodysplastic syndromes, like acute myeloid leukemia, benefit from a chemotherapy drug called decitabine that stunts cancer growth. But many others are resistant to decatibine's effects or become resistant over time.

16 Nov 2023

Diabetes linked to higher colorectal cancer risk in low-income African-Americans, study shows

JAMA Network Open study finds that diabetes increases colorectal cancer risk among low-income African-American individuals, with stronger associations observed in women, smokers, and those recently diagnosed, suggesting that glycemic control and colonoscopy screenings could mitigate risk.

16 Nov 2023

Circadian rest-activity patterns may signal frailty risk in older adults

Brigham researchers found an association between alterations in circadian rest-activity rhythms and risk of frailty incidence in older adults.

16 Nov 2023

Researchers discover genetic mechanism behind pancreatic cancer metastasis

Pancreatic cancer is tricky to manage because it spreads easily and early, and the tumors have a unique biological makeup.

15 Nov 2023

Study reveals weight-related differences in daily energy burning

Weight influences how and when bodies burn energy, new research indicates.

15 Nov 2023

Intestinal MCT1 plays a crucial role in sex-dependent metabolic regulation

Monocarboxylate transporter 1 (MCT1) plays a crucial role in the transport of lactate, pyruvate, ketone bodies, and short-chain fatty acids (SCFA), as well as MCT1-targeted drugs in various tissues.

14 Nov 2023

Microglia found to play crucial role in early human brain development

An international team of scientists has uncovered the vital role of microglia, the immune cells in the brain that acts as its dedicated defense team, in early human brain development.

14 Nov 2023

Drinking coffee regularly may help prevent irritable bowel syndrome

Study reveals that coffee consumption is associated with a reduced risk of developing irritable bowel syndrome (IBS), as determined by a systematic review and meta-analysis of global studies.

14 Nov 2023

Bioengineered human heart muscle cells and micro-tissues take flight to space

Mount Sinai's Cardiovascular Research Institute is sending bioengineered human heart muscle cells and micro-tissues into space for the first time on NASA's 29th SpaceX commercial resupply services mission, which launched Thursday, November 9.

14 Nov 2023

Traffic emissions disrupt gene expression in human olfactory cells

Exposure to ultrafine particles from traffic alters the expression of many genes in human olfactory mucosa cells, a new study shows.

14 Nov 2023

New study sheds light on the genes and nutrients that give MAIT cells their fighting power

Scientists at La Jolla Institute for Immunology (LJI) are investigating a talented type of T cell.

10 Nov 2023

Brazzein and monellin: Safe alternatives to sugar, new research confirms

Toxicity assessments of monellin and brazzein.

10 Nov 2023

Preclinical discovery could point the way toward better treatments for type 2 diabetes

A drug currently in clinical trials as a cancer therapy can also stimulate pancreatic beta cells to secrete insulin, revealing a previously unknown mechanism for insulin regulation in type 2 diabetes, according to a new study by Weill Cornell Medicine investigators.

9 Nov 2023