Metabolism News and Research

Latest Metabolism News and Research

Mitochondrial dysfunction observed in children with full syndrome autism

Preliminary research has found that children with autism are more likely to have impaired mitochondrial function (structures within cells responsible for energy production) and mitochondrial DNA abnormalities than typically developing children, according to a study in the December 1 issue of JAMA.

1 Dec 2010

Age-related hearing loss associated with low serum levels of folic acid in the elderly

Age-related hearing loss (ARHL), one of the four most prevalent chronic conditions in the elderly, is associated with low serum levels of folic acid, according to new research published in the December 2010 issue of Otolaryngology - Head and Neck Surgery.

1 Dec 2010

Roche NimbleGen announces NewGene as first certified service provider in the UK

Roche NimbleGen announces that Newcastle-based genomic services provider NewGene Ltd. has officially become a Certified Service Provider (CSP) for NimbleGen Sequence Capture. They will provide services for NimbleGen Sequence Capture Arrays with sequencing on the Genome Sequencer FLX System from 454 Life Sciences, a Roche Company.

1 Dec 2010

Scientists create couch potato mouse model to study muscle function

Daniel Kelly, M.D., and his colleagues at Sanford-Burnham Medical Research Institute (Sanford-Burnham) at Lake Nona have unveiled a surprising new model for studying muscle function: the couch potato mouse.

1 Dec 2010

Study finds boosting glucose levels can reduce aggressive behavior

A spoonful of sugar may be enough to cool a hot temper, at least for a short time, according to new research. A study found that people who drank a glass of lemonade sweetened with sugar acted less aggressively toward a stranger a few minutes later than did people who consumed lemonade with a sugar substitute.

1 Dec 2010

BioTrends releases annual syndicated publication of CKD-ND patient charts

BioTrends Research Group, Inc. released ChartTrends: Bone and Mineral Metabolism in Chronic Kidney Disease Non-Dialysis (CKD-ND), an annual syndicated publication based on patient and laboratory data collected from over 1,000 U.S.

30 Nov 2010

Researchers conduct real-time metabolic imaging in human patient with prostate tumor

A UCSF research collaboration with GE Healthcare has produced the first results in humans of a new technology that promises to rapidly assess the presence and aggressiveness of prostate tumors in real time, by imaging the tumor's metabolism.

30 Nov 2010

New tool to trace metabolism of carotenoids in human body

The University of Illinois scientists who linked eating tomatoes with a reduced risk of prostate cancer have developed a tool that will help them trace the metabolism of tomato carotenoids in the human body. And they've secured funding from the National Institutes of Health to do it.

30 Nov 2010

Transgenomic signs definitive agreement to acquire diagnostic business of Clinical Data

Transgenomic, Inc. announced today the signing of a definitive agreement for Transgenomic to acquire the diagnostic business of Clinical Data, Inc. This acquisition includes a suite of proprietary genetic commercial tests, certain proprietary biomarker assays, and the CLIA-certified laboratory operations of Clinical Data for a purchase price of approximately $15.4 million, primarily in cash and notes.

29 Nov 2010

Merck announces initial results from ISENTRESS Phase III study in HIV-1

Merck today reported initial results from the Phase III study investigating the efficacy and safety of a treatment regimen including ISENTRESS® (raltegravir) Tablets once daily in treatment-naïve adult patients infected with HIV-1. ISENTRESS is indicated in combination with other antiretroviral agents for the treatment of HIV-1 infection in treatment-naïve and treatment-experienced adults.

29 Nov 2010

NIH awards $6.7M to establish Membrane Protein Structural Biology Consortium

Dr. Michael G. Malkowski, Hauptman-Woodward senior research scientist, has received a $6.7 million grant from the National Institutes of Health in support of his work to establish the Membrane Protein Structural Biology Consortium (mpsbc.org) as one of nine centers in the United States responsible for determining membrane protein structures within a larger NIH biology-based initiative.

26 Nov 2010

Study suggests less than 10% of UK adults with CAH receive specialist endocrine care

A new study suggests that less than 10% of the estimated 3,591 adults in the UK with the genetic condition congenital adrenal hyperplasia (CAH) receive specialist endocrine care, and that there is no standard treatment for these patients.

26 Nov 2010

Diogenes study investigates optimum diet composition for preventing, treating obesity

Researchers at the Faculty of Life Sciences (LIFE), University of Copenhagen, can now unveil the results of the world's largest diet study: If you want to lose weight, you should maintain a diet that is high in proteins with more lean meat, low-fat dairy products and beans and fewer finely refined starch calories such as white bread and white rice.

25 Nov 2010

New genomic approach to evaluate suspicious thyroid nodules

Doctors at the University of Colorado School of Medicine were concerned recently when they found a nodule in the thyroid of a 64-year-old Colorado man. They extracted cells from the nodule, hoping to determine whether the man had cancer. But the biopsy results were inconclusive.

24 Nov 2010

Different digestive tract bacteria helps infants digest milk more effectively than adults

Infants are more efficient at digesting and utilizing nutritional components of milk than adults due to a difference in the strains of bacteria that dominate their digestive tracts. Researchers from the University of California, Davis, and Utah State University report on genomic analysis of these strains in the November 2010 issue of the journal Applied and Environmental Microbiology identifying the genes that are most likely responsible for this difference.

23 Nov 2010

$S*BIO begins SB1317 Phase 1 clinical trial in patients with advanced/refractory hematologic malignancies$

S*BIO begins SB1317 Phase 1 clinical trial in patients with advanced/refractory hematologic malignancies

S*BIO Pte Ltd today announced that a fourth novel, potential best-in-class compound discovered and developed by S*BIO has entered a Phase 1 clinical trial. The initiation of the study for S*BIO's oral multi-kinase inhibitor, SB1317 or TG02, in patients with advanced/refractory hematologic malignancies has triggered a payment from S*BIO's development and commercialization partner for the program, Tragara Pharmaceuticals.

22 Nov 2010

Agilent's GeneSpring Bioinformatics Solution integrated with GeneGo's MetaCore

GeneGo, Inc., a leading provider of databases, software and services in systems biology and chemistry, and Agilent Technologies, Inc., the world's premier measurement company and a technology leader in chemical analysis, life sciences, electronics and communications, announced today that they have integrated Agilent's GeneSpring Bioinformatics Solution with MetaCore.

22 Nov 2010

Stealth Peptides introduces Bendavia clinical candidate at AHA Scientific Sessions

Stealth Peptides, a privately held biopharmaceutical company developing innovative mitochondrial therapies for diseases with significant unmet medical needs, introduced its lead clinical candidate, Bendavia, a novel compound that targets the mitochondrion, at the 2010 American Heart Association's (AHA) Scientific Sessions, Resuscitation Science Symposium.

22 Nov 2010

VYTORIN reduces major vascular events in patients with chronic kidney disease

In a new investigational study of VYTORIN, the cholesterol-lowering medicine from Merck, VYTORIN 10/20 mg reduced the incidence of first major vascular events defined as non-fatal heart attacks or cardiac death, stroke or any revascularization procedure by a highly statistically significant 16.1 percent compared to placebo, Study of Heart and Renal Protection study involved more than 9,000 patients who, on average, had advanced or end-stage chronic kidney disease (CKD)

22 Nov 2010

Researchers develop three-dimensional cancer cell from normal human tissue in culture dish

Researchers at the Stanford University School of Medicine have successfully transformed normal human tissue into three-dimensional cancers in a tissue culture dish for the first time. Watching how the cells behave as they divide and invade surrounding tissue will help physicians better understand how human cancers act in the body. The new technique also provides a way to quickly and cheaply test anti-cancer drugs without requiring laboratory animals.

22 Nov 2010

Metabolism News and Research

Latest Metabolism News and Research

Mitochondrial dysfunction observed in children with full syndrome autism

Age-related hearing loss associated with low serum levels of folic acid in the elderly

Roche NimbleGen announces NewGene as first certified service provider in the UK

Scientists create couch potato mouse model to study muscle function

Study finds boosting glucose levels can reduce aggressive behavior

BioTrends releases annual syndicated publication of CKD-ND patient charts

Researchers conduct real-time metabolic imaging in human patient with prostate tumor

New tool to trace metabolism of carotenoids in human body

Transgenomic signs definitive agreement to acquire diagnostic business of Clinical Data

Merck announces initial results from ISENTRESS Phase III study in HIV-1

NIH awards $6.7M to establish Membrane Protein Structural Biology Consortium

Study suggests less than 10% of UK adults with CAH receive specialist endocrine care

Diogenes study investigates optimum diet composition for preventing, treating obesity

New genomic approach to evaluate suspicious thyroid nodules

Different digestive tract bacteria helps infants digest milk more effectively than adults

S*BIO begins SB1317 Phase 1 clinical trial in patients with advanced/refractory hematologic malignancies

Agilent's GeneSpring Bioinformatics Solution integrated with GeneGo's MetaCore

Stealth Peptides introduces Bendavia clinical candidate at AHA Scientific Sessions

VYTORIN reduces major vascular events in patients with chronic kidney disease

Researchers develop three-dimensional cancer cell from normal human tissue in culture dish

Clue's CEO Rhiannon White on the Future of Femtech and PCOS

Freezing Point Osmometry in Life Science Applications

Precision in every drop: Inside Hamilton’s syringe technology