Metabolism News and Research

Latest Metabolism News and Research

AACE, AME and ETA jointly publish guidelines for diagnosis and management of thyroid nodules

Three of the world's most respected medical associations for the treatment of thyroid disease recently issued joint guidelines for the diagnosis and management of thyroid nodules. The American Association of Clinical Endocrinologists, the Associazione Medici Endocrinologi and European Thyroid Association jointly published the guidelines online this week, and the executive summary will be published in the next issue of their respective journals.

20 May 2010

Phase I study of SNS-032 demonstrates safety, potential clinical activity in treating B-cell malignancies

A Phase I clinical trial of SNS-032, one of the first in a new class of drugs that inhibit cyclin-dependent kinases, demonstrated the drug's safety and potential clinical action against advanced chronic lymphocytic leukemia. Cyclin-dependent kinases are enzymatic proteins that are integrally involved in cellular metabolism, renewal and signaling, and are thought to play key roles in the growth of cancers.

20 May 2010

Riga to host 3rd Baltic Congress of Osteoporosis

Riga, Latvia will be the venue for the 3rd Baltic Congress of Osteoporosis which will take place on September 3-4, 2010. The congress, to be held in English, is jointly organized by the Latvian Osteoporosis and Bone Metabolism Diseases Association, Lithuanian Osteoporosis Foundation, Lithuanian Association of Metabolic Bone Diseases and the Estonian Osteoporosis Society.

19 May 2010

Research team converts astroglia into two main classes of cortical neurons

The research team led by Professor Magdalena Götz of Helmholtz Zentrum München and Ludwig-Maximilians-Universität (LMU) Munich reports a major step forward in discovering a therapy for neurodegenerative diseases such as Alzheimer's or stroke. The researchers were able to convert glial cells of the brain into two different functional classes of neurons. The findings are published on May 18th in the renowned journal PLoS Biology.

19 May 2010

PET scanning provides great insight into immune response

A commonly used probe for Positron Emission Tomography scanning and a new probe developed by researchers at UCLA reveal different functions in diverse cells of the immune system, providing a non-invasive and much clearer picture of an immune response in action.

19 May 2010

Roche Diagnostics, ACC collaborate to develop biomarkers clinical resource Web portal

Roche Diagnostics and the American College of Cardiology have begun a unique collaboration to develop a peer-reviewed biomarkers clinical resource Web portal.

From Roche Sequencing and Life Science 19 May 2010

Roche, Biogen Idec discontinue ocrelizumab clinical development programme for RA

Roche and Biogen Idec today announced their decision to discontinue the ocrelizumab clinical development programme in patients with rheumatoid arthritis (RA).

19 May 2010

Jonas Brothers help raise funds for Childrens Hospital Los Angeles during Rock For Diabetes event

The multi-platinum album selling and Grammy nominated music artists, Jonas Brothers, joined more than 200 guests at the home of Danny DeVito and Rhea Perlman on Sunday, May 16 during the annual "Rock For Diabetes" event, to help raise funds for the Center for Endocrinology, Diabetes and Metabolism at Childrens Hospital Los Angeles. Performing a special live show for attendees, the event raised more than $250,000 for the Center.

18 May 2010

FDA accepts for filing Sigma-Tau Pharmaceuticals' cysteamine hydrochloride ophthalmic solution NDA

Sigma-Tau Pharmaceuticals, Inc. announced today that the U.S. Food and Drug Administration (FDA) has accepted the filing of the company's new drug application (NDA) for its cysteamine hydrochloride ophthalmic solution, an investigational therapy for the treatment of corneal cystine crystals in patients with cystinosis. The FDA also granted the NDA Priority Review status, a designation given to drugs that may provide major advances or a treatment where no adequate therapy exists.

18 May 2010

Asthma patients need to avoid heavy, high-fat meals: New research

People with asthma may be well-advised to avoid heavy, high-fat meals, according to new research. Individuals with asthma who consumed a high-fat meal showed increased airway inflammation just hours after the binge, according to Australian researchers who conducted the study.

17 May 2010

Study identifies potential noninvasive biomarkers in NAFLD, NASH using Metabolon's platform

Metabolon, Inc. announces a study published in the Metabolism Journal released in the paper on April 28, 2010, by Satish C. Kalhan.

17 May 2010

Redpoint Bio first-quarter 2010 net loss reduces to $1.7 million

Redpoint Bio Corporation, a company focused on the development of healthier foods and beverages and new approaches to the treatment of diabetes and obesity, today announced financial and operational results for the first quarter ended March 31, 2010.

14 May 2010

Interleukin Genetics reports 166% increase in overall genetic test revenue for first-quarter 2010

Interleukin Genetics, Inc. announced today financial and operational results for the first quarter ended March 31, 2010.

14 May 2010

MitoSciences awarded $590,000 to support development of companion diagnostic tests for antiviral drugs

MitoSciences announces that it has just been awarded $590,000 by the National Institutes of Health to support the development of companion diagnostic tests for antiviral drugs. The award was made after competitive scientific review and was issued under The American Recovery and Reinvestment Act of 2009.

14 May 2010

Celsis IVT settles LiverPool patent infringement suit, XenoTech to stop sale of CryoXTreme products

Celsis International Ltd. announced today that Celsis In Vitro, Inc. has reached a settlement agreement with XenoTech, LLC, Sekisui Chemical Co. Ltd., and Sekisui Medical Co. Ltd. in a patent infringement lawsuit filed by Celsis IVT on February 2, 2010.

14 May 2010

Study shows direct cellular interaction between endocannabinoids and alcohol in the brain

In findings that should finally put to rest a decade of controversy in the field of neurobiology, a team at The Scripps Research Institute has found decisive evidence that a specific neurotransmitter system-the endocannabinoid system-is active in a brain region known to play a key role in the processing of memory, emotional reactions, and addiction formation. The new study also shows that this system can dampen the effects of alcohol, suggesting an avenue for the development of drugs to combat alcohol addiction.

13 May 2010

SAGE launches further two Therapeutic Advances journals

SAGE has extended its suite of Therapeutic Advances journals with the launch of a further two titles: Therapeutic Advances in Chronic Disease and Therapeutic Advances in Endocrinology and Metabolism.

13 May 2010

$High dose Vitamin D linked to high rate of fractures and falls$

High dose Vitamin D linked to high rate of fractures and falls

Many women have been regularly taking vitamin D supplements in the hope that it is good for their bones. However a new study has shown that high doses of this vitamin can actually increase the number of falls and fractures in older women.

12 May 2010

Optivia Biotechnology launches OptiDDI Suite for assessing transporter-related DDIs

Optivia Biotechnology Inc., a leading provider of in vitro transporter assay services, today announced the launch of the OptiDDITM Suite, a novel assay panel that assesses the most clinically significant transporter-related drug-drug interactions (DDIs), as identified by the International Transporter Consortium (ITC) in its report "Membrane Transporters in Drug Development" (Nature Reviews-Drug Discovery, March 2010).

12 May 2010

$Study shows high-dose vitamin D therapy may increase risk of fracture in elderly women$

Study shows high-dose vitamin D therapy may increase risk of fracture in elderly women

Women age 70 years or older who received a single annual high dose of vitamin D had a higher rate of falls and fractures compared to women who received placebo, according to a study in the May 12 issue of JAMA.

12 May 2010

Metabolism News and Research

Latest Metabolism News and Research

AACE, AME and ETA jointly publish guidelines for diagnosis and management of thyroid nodules

Phase I study of SNS-032 demonstrates safety, potential clinical activity in treating B-cell malignancies

Riga to host 3rd Baltic Congress of Osteoporosis

Research team converts astroglia into two main classes of cortical neurons

PET scanning provides great insight into immune response

Roche Diagnostics, ACC collaborate to develop biomarkers clinical resource Web portal

Roche, Biogen Idec discontinue ocrelizumab clinical development programme for RA

Jonas Brothers help raise funds for Childrens Hospital Los Angeles during Rock For Diabetes event

FDA accepts for filing Sigma-Tau Pharmaceuticals' cysteamine hydrochloride ophthalmic solution NDA

Asthma patients need to avoid heavy, high-fat meals: New research

Study identifies potential noninvasive biomarkers in NAFLD, NASH using Metabolon's platform

Redpoint Bio first-quarter 2010 net loss reduces to $1.7 million

Interleukin Genetics reports 166% increase in overall genetic test revenue for first-quarter 2010

MitoSciences awarded $590,000 to support development of companion diagnostic tests for antiviral drugs

Celsis IVT settles LiverPool patent infringement suit, XenoTech to stop sale of CryoXTreme products

Study shows direct cellular interaction between endocannabinoids and alcohol in the brain

SAGE launches further two Therapeutic Advances journals

High dose Vitamin D linked to high rate of fractures and falls

Optivia Biotechnology launches OptiDDI Suite for assessing transporter-related DDIs

Study shows high-dose vitamin D therapy may increase risk of fracture in elderly women

Precision in every drop: Inside Hamilton’s syringe technology

Exploring the Future of Neuroscience Drug Discovery

Genomic conservation in Thailand's mangroves