Metabolism News and Research

Latest Metabolism News and Research

Study: Fat tissue in women with PCOS produces inadequate amount of hormone

Fat tissue in women with Polycystic Ovary Syndrome produces an inadequate amount of the hormone that regulates how fats and glucose are processed, promoting increased insulin resistance and inflammation, glucose intolerance, and greater risk of diabetes and heart disease, according to a study conducted at the Center for Androgen-Related Research and Discovery at Cedars-Sinai Medical Center.

3 Feb 2010

Scientists are getting closer to prove how cholesterol causes heart disease

By considering molecular-level events on a broader scale, researchers now have a clearer, if more complicated, picture of how one class of immune cells goes wrong when loaded with cholesterol. The findings reported in the February 3rd issue of Cell Metabolism, a Cell Press publication, show that, when it comes to the development of atherosclerosis and heart disease, it's not about any one bad actor-it's about a network gone awry.

3 Feb 2010

AACE approves A1c as additional diagnostic criterion for type 2 diabetes

The American Association of Clinical Endocrinologists (AACE) today has approved the use of A1c as an additional diagnostic criterion for type 2 diabetes. An A1c of 6.5 or greater is now considered an alternate criterion for the diagnosis of type 2 diabetes.

3 Feb 2010

Repros Therapeutics receives FDA confirmation for initiating Androxal IND

Repros Therapeutics Inc. today announced that the Company has received verbal confirmation from the Division of Metabolic and Endocrine Drug Products of the Food and Drug Agency that the Company may initiate its Investigational New Drug Application for the study of oral Androxal® in the treatment of hypogonadal men with Type II Diabetes (T2D) with a Phase IIa trial.

3 Feb 2010

Fat tissue in PCOS patients may predispose them to diabetes and heart disease

3 Feb 2010

Celsis IVT alleges patent infringement, files lawsuit against Sekisui Chemical and subsidiaries

Celsis In Vitro, Inc. announced today that it has filed a patent infringement lawsuit against XenoTech LLC, Sekisui Chemical Co. Ltd., and Sekisui Medical Co. Ltd. in the United States District Court for the Northern District of Illinois in Chicago. XenoTech and Sekisui Medical are wholly-owned subsidiaries of Sekisui Chemical.

3 Feb 2010

Entelos awarded U.S. patent for apparatus and methods of assessing metabolic substrate utilization

Entelos, Inc., a simulation and modeling company focused on human health, announced today that the U.S. Patent and Trademark Office has granted U.S. Patent No. 7,654,955 entitled “Apparatus and Methods for Assessing Metabolic Substrate Utilization” to the Company. These methods further strengthen the Entelos® Metabolism PhysioLab® platform and leverage insights about human physiology that can lead to improved diagnosis, clinical testing, and personalized treatment across a highly variable patient population.

2 Feb 2010

Researchers discover new mechanism to burn body fat

Researchers reporting in the February 3rd issue of Cell Metabolism may have a new way to trick the body into consuming more energy. The target in this case is an enzyme that indirectly controls the activity of what the researchers refer to as the "energy master switch." It boils down to this:

2 Feb 2010

Tubing-Free Insulin Pump System improves glycemic control in diabetic patients

Albany College of Pharmacy and Health Sciences and The Endocrine Group researchers have concluded that the OmniPod® Insulin Management System significantly improved blood glucose control in diabetes patients who previously received insulin through multiple daily injections. The retrospective study results were published in the latest issue of Infusystems USA, in a study titled, 'Clinical Experience with a Tubing-Free Insulin Pump System.'

2 Feb 2010

Positive results from Phosphagenics' TPM Phase 1B clinical study for transdermal delivery of oxycodone

Phosphagenics Limited today announced positive results from a Phase 1B clinical study using the Company’s patented TPM™ (Targeted Penetration Matrix) for the transdermal delivery of oxycodone. The results of the successful trial demonstrate that daily application of a TPM™ patch delivers therapeutic levels of oxycodone into the blood stream in a reproducible, consistent and sustained manner.

2 Feb 2010

Long-chain omega-3 polyunsaturated fatty acids may reduce risk of psychotic disorders

Individuals at extremely high risk of developing psychosis appear less likely to develop psychotic disorders following a 12-week course of fish oil capsules containing long-chain omega-3 polyunsaturated fatty acids, according to a report in the February issue of Archives of General Psychiatry, one of the JAMA/Archives journals.

2 Feb 2010

$Study shows hip fractures in elderly men are linked to impaired bone health in their grandsons$

Study shows hip fractures in elderly men are linked to impaired bone health in their grandsons

If your grandfather has had a hip fracture, you too could be at risk. Researchers at the Sahlgrenska Academy at the University of Gothenburg, Sweden, have been able to show, for the first time, a link between hip fractures in elderly men and impaired bone health in their grandsons.

30 Jan 2010

Global market for oncology drugs is forecast to reach $80 billion by 2050

New Medicine's Oncology KnowledgeBASE (nm/OK) residing at http://nmok.net became available on the Internet 10 years ago and, since then, the oncology field has evolved into one of the most challenging, complex and promising drug development sectors, both in terms of its potential contribution to medicine and to its market opportunities.

29 Jan 2010

Hormones & Cancer: A new journal from The Endocrine Society

Today, The Endocrine Society unveiled its newest journal, Hormones & Cancer. This bi-monthly journal will include research articles covering all aspects of hormone action on cancer causation, progression, dependence, prevention, resistance and treatment.

29 Jan 2010

Targeted sequencing of exome can help identify potential disease-causing genes

Researchers from University of Miami Miller School of Medicine and Roche Applied Science have recently published a research study on human exome resequencing results from eight individuals that span across three generations of a family. The findings of this study showcased the value of targeted enrichment for family-based studies which allows researchers to quickly identify potential disease-causing genetic variants and will provide the data and information for further research to better understand disease and the impact across generations of a family.

29 Jan 2010

Health benefits of aerobics can be greatly affected by what you eat after exercise

Many of the health benefits of aerobic exercise are due to the most recent exercise session (rather than weeks, months and even years of exercise training), and the nature of these benefits can be greatly affected by the food we eat afterwards, according to a study published in the Journal of Applied Physiology (http://jap.physiology.org).

29 Jan 2010

Scientists discover mechanism that regulates prolactin hormone

A mechanism for regulating the hormone prolactin has newly been revealed by scientists at Karolinska Institutet. The results are to be published in the scientific journal Neuron, and may be significant for conditions and functions such as breast-feeding, sexual libido, and metabolism.

28 Jan 2010

Study shows cooling technique in heart operations does not impair neurological outcomes in children

Congenital heart defects (CHD) are the most common birth defects in humans, affecting 8 per 1000 live births with one third of affected children requiring intervention in early infancy.

28 Jan 2010

Automated measurements more reliable in moderate cases of knee degeneration

Scientists have automated the measurement of a vital part of the knee in images with a computer program that performs much faster and just as reliably as humans who interpret the same images.

28 Jan 2010

Alli boosts weight loss and reduces excess visceral fat

New studies show that overweight and obese people using alli® (orlistat 60 mg) with a reduced calorie, lower-fat diet can significantly reduce weight, visceral fat, and waist circumference and therefore may reduce their risk of type 2 diabetes, hypertension, heart disease and stroke.

28 Jan 2010

Metabolism News and Research

Latest Metabolism News and Research

Study: Fat tissue in women with PCOS produces inadequate amount of hormone

Scientists are getting closer to prove how cholesterol causes heart disease

AACE approves A1c as additional diagnostic criterion for type 2 diabetes

Repros Therapeutics receives FDA confirmation for initiating Androxal IND

Fat tissue in PCOS patients may predispose them to diabetes and heart disease

Celsis IVT alleges patent infringement, files lawsuit against Sekisui Chemical and subsidiaries

Entelos awarded U.S. patent for apparatus and methods of assessing metabolic substrate utilization

Researchers discover new mechanism to burn body fat

Tubing-Free Insulin Pump System improves glycemic control in diabetic patients

Positive results from Phosphagenics' TPM Phase 1B clinical study for transdermal delivery of oxycodone

Long-chain omega-3 polyunsaturated fatty acids may reduce risk of psychotic disorders

Study shows hip fractures in elderly men are linked to impaired bone health in their grandsons

Global market for oncology drugs is forecast to reach $80 billion by 2050

Hormones & Cancer: A new journal from The Endocrine Society

Targeted sequencing of exome can help identify potential disease-causing genes

Health benefits of aerobics can be greatly affected by what you eat after exercise

Scientists discover mechanism that regulates prolactin hormone

Study shows cooling technique in heart operations does not impair neurological outcomes in children

Automated measurements more reliable in moderate cases of knee degeneration

Alli boosts weight loss and reduces excess visceral fat

Precision in every drop: Inside Hamilton’s syringe technology

Exploring the Future of Neuroscience Drug Discovery

Genomic conservation in Thailand's mangroves