Metabolism News and Research

Latest Metabolism News and Research

U-M study finds shorter sleep duration for 9- to 12-year-old kids is associated with increased risk for being overweight

Diets high in fat and sugar may not be the only things contributing to American children's expanding waistlines. Research findings from the University of Michigan C.S. Mott Children's Hospital suggest that kids who aren't getting enough sleep also may be at an increased risk for being overweight.

5 Nov 2007

Mice predict the effectiveness of orally taken drugs

The amount of an orally taken drug that makes it to the site in the body at which it exerts its effects is much lower than the amount of an intravenously administered drug and it varies considerably between individuals.

2 Nov 2007

Case Western Reserve researchers breed a "Lance Armstrong" mouse

Case Western Reserve University researchers have bred a line of "mighty mice" (PEPCK-Cmus mice) that have the capability of running five to six kilometers at a speed of 20 meters per minute on a treadmill for up to six hours before stopping.

2 Nov 2007

Attenuation of NASH by stimulation of free fatty acid metabolism

Medically-complicated obesity is a societal problem that needs to be solved. Liver disease, specifically non-alcoholic steatohepatitis or NASH, is just one of the many complications of increased body weight.

28 Oct 2007

Many medical disorders may be languishing in mountains of discarded gene data

Previously hidden obesity-related genes have been uncovered from old experiments by researchers at the Stanford University School of Medicine and Lucile Packard Children's Hospital.

24 Oct 2007

Cellular power plant fault explains abnormal metabolism of tumours

The increased consumption of glucose that tumour cells exhibit, was thought to be a cause of the extra demand of building blocks required to keep up with an uncontrolled cell growth, but now it is more accepted that it could be the effect of a programmed metabolic change that favours this malignant growth.

23 Oct 2007

Sleep-deprivation causes brain to overreact to negative experiences

Without sleep, the emotional centers of the brain dramatically overreact to negative experiences, reveals a new brain imaging study in the October 23rd issue of Current Biology, a publication of Cell Press.

22 Oct 2007

Heparanase shows potential as cancer drug

Laboratory experiments have previously shown that cancer cells overproduce an enzyme, heparanase, which splits the body's own polysaccharide heparan sulfate into shorter fragments.

22 Oct 2007

Exercise improves thinking and reduces diabetes in overweight kids

Just three months of daily, vigorous physical activity in overweight children improves their thinking and reduces their diabetes risk, researchers say.

22 Oct 2007

Longer-living, healthier mouse holds clues to human ageing

A study by scientists at UCL (University College London) shows that mice lacking the insulin receptor substrate (IRS)-1 are more resistant to ageing than normal mice.

22 Oct 2007

The accumulation of sugar in neurons may explain the origin of several neurodegenerative diseases

A phenomenon considered healthy for cells, such as the accumulation of long chains of glucose (glycogen), which tissues store for energy purposes, is harmful for neurons.

22 Oct 2007

Bacteria use plant defence for genetic modification

Bacteria that cause tumours in plants modify plant genomes by skilfully exploiting the plants' first line of defence.

22 Oct 2007

Pine bark extract boosts nitric oxide production

A study to be published in the October edition of Hypertension Research reveals Pycnogenol, (pic-noj-en-all), an antioxidant plant extract from the bark of the French maritime pine tree, helps individuals by enhancing healthy nitric oxide (NO) production which leads to an increase in blood flow and oxygen supply to muscles.

18 Oct 2007

Connection between expression of clock genes and sleep

Genes responsible for our 24 hour body clock influence not only the timing of sleep, but also appear to be central to the actual restorative process of sleep, according to research published in the online open access journal BMC Neuroscience.

18 Oct 2007

Exercise, osteopenia and men

According to the National Osteoporosis Foundation, osteoporosis affects more than 2 million men in the United States and nearly 12 million more have osteopenia - clinically significant low bone density that is less severe than osteoporosis.

17 Oct 2007

Severely mentally ill at high risk for cardiovascular disease

A psychiatrist at Washington University School of Medicine in St. Louis writes in the Journal of the American Medical Association (JAMA) that although mortality from cardiovascular disease has declined in the United States over the past several decades, patients with severe psychiatric illness are not enjoying the benefits of that progress.

17 Oct 2007

Genetics play a key role in obesity

New evidence that genetics plays a key role in obesity is published today in the International Journal of Bioinformatics Research and Applications.

17 Oct 2007

Low levels of testosterone may increase risk of death in older men

Older men with low levels of testosterone may have an increased long-term risk of death compared to men with normal testosterone, according to a new study accepted for publication in the Journal of Clinical Endocrinology & Metabolism (JCEM) .

16 Oct 2007

Blood levels of progesterone may impact blood vessel function

Blood levels of progesterone, a major female sex hormone, may play an important role in modifying vascular function in postmenopausal women, according to a new study accepted for publication in the Journal of Clinical Endocrinology & Metabolism (JCEM).

16 Oct 2007