Metabolism News and Research

Latest Metabolism News and Research

Glucokinase activators induce hepatic lipid accumulation in mice with high-fat diet

The researchers demonstrated that glucokinase activation was effective in lowering blood glucose in mice with high-fat diet-induced obesity, while it potentially raised the risk of increasing hepatic lipid accumulation that triggered the PERK-UPR pathway.

11 Aug 2023

CRISPR/sgRNA-SAM therapy: a potential breakthrough for Parkinson's disease?

Researchers utilize the CRISPR-Cas9 system to induce the synthesis of dopamine (DA) in the brains of a rat model for Parkinson’s disease.

11 Aug 2023

Personalized exercise testing may be more effective for fat loss

The best heart rate for burning fat differs for each individual and often does not align with the "fat burning zone" on commercial exercise machines, Icahn School of Medicine at Mount Sinai researchers report.

11 Aug 2023

A drug for heart conditions improves efficacy of melanoma therapies

A collaborative study undertaken by the Navarrabiomed Biomedical Research Center (Pamplona, Navarre), the Institute of Neurosciences CSIC-UMH (Sant Joan d'Alacant, Valencian Community) and IRB Barcelona (Barcelona, Catalonia) shows that the administration of ranolazine, a drug currently used to treat heart conditions, improves the efficacy of current therapies for melanoma, in mouse models of this disease.

10 Aug 2023

New mechanism discovered for brain repair after ischemic stroke

Patients often experience functional decline after an ischemic stroke, especially due to the brain's resistance to regenerate after damage.

10 Aug 2023

Experimental drug can reduce symptoms of inflammatory bowel disease in pre-clinical models

A new study of mice and lab-grown human colon "organoids" indicates that an experimental drug developed by Johns Hopkins Medicine researchers can substantially reduce symptoms of inflammatory bowel disease (IBD) in pre-clinical models.

10 Aug 2023

The role of estrogen in osteoarthritis and lower back pain

Researchers review existing evidence on the association between estrogen, osteoarthritis, and lower back pain.

10 Aug 2023

Study detects biomarker changes nearly 30 years before symptom onset of Alzheimer’s disease

A new paper has shown how Alzheimer’s disease pathology comes into being over a period of almost three decades.

10 Aug 2023

Tau PET shows promise for early diagnosis and treatment of Alzheimer's disease

Alzheimer's disease, one of the most common neurodegenerative diseases, leads to progressive loss of memory and autonomy.

9 Aug 2023

Yale researchers create "humanized" liver in living mice to study chronic liver diseases

Yale researchers have created a functional "humanized" liver in living mice that will help scientists find human-specific mechanisms for regulating cholesterol levels and potentially for treating chronic liver diseases afflicting tens of millions of people in the United States.

9 Aug 2023

Mice lacking TMCO3 gene have shortened bones

Through next-generation sequencing, investigators have identified a mutation in the TMCO3 gene in two sisters with short stature.

9 Aug 2023

Particulate matter air pollution linked to increased cardiovascular disease death and disability worldwide

The impact of particulate matter air pollution on death and disability is on the rise worldwide, according to new research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

9 Aug 2023

Review examines visual disturbances among Parkinson’s disease patients

In a recent review published in Brain Sciences, researchers reviewed existing data on visual impairments among Parkinson’s disease (PD) patients.

9 Aug 2023

High-level BPA exposure may affect male fertility

Scientists discuss the effect of bisphenol A on human male fertility.

9 Aug 2023

Cytochromes P450 enzymes exhibit unique soft-robotic properties, study reveals

Study reveals an important discovery in the realm of nanomachines within living systems.

8 Aug 2023

Link found between vitamin D deficiency and metabolic abnormalities in children: New insights unveiled

Researchers investigated the correlation between vitamin D deficiency and metabolic syndrome (MetS) components.

8 Aug 2023

Impact of age-related alterations in lipid metabolism on general health

Scientists provide a detailed overview on age-related alterations in lipid metabolism and its association with age-related chronic diseases.

8 Aug 2023

Bone mineralization found to dampen metastatic progression of breast cancer

Tumor cells are known to be fickle sleeper agents, often lying dormant in distant tissues for years before reactivating and forming metastasis.

7 Aug 2023

Childhood abuse can induce stress that changes neural networks and functions during growth

Childhood neglect and/or abuse can induce extreme stress that significantly changes neural networks and functions during growth. This can lead to mental illnesses, including depression and schizophrenia, but the exact mechanism and means to control it were yet to be discovered.

4 Aug 2023

Study reports the first protein-based diagnostic signature to discriminate MIS-C from Kawasaki Disease and other common infections

Researchers explore the distinguishing features of MIS-C as compared to other inflammatory-infectious syndromes in children.

4 Aug 2023

Metabolism News and Research

Latest Metabolism News and Research

Glucokinase activators induce hepatic lipid accumulation in mice with high-fat diet

CRISPR/sgRNA-SAM therapy: a potential breakthrough for Parkinson's disease?

Personalized exercise testing may be more effective for fat loss

A drug for heart conditions improves efficacy of melanoma therapies

New mechanism discovered for brain repair after ischemic stroke

Experimental drug can reduce symptoms of inflammatory bowel disease in pre-clinical models

The role of estrogen in osteoarthritis and lower back pain

Study detects biomarker changes nearly 30 years before symptom onset of Alzheimer’s disease

Tau PET shows promise for early diagnosis and treatment of Alzheimer's disease

Yale researchers create "humanized" liver in living mice to study chronic liver diseases

Mice lacking TMCO3 gene have shortened bones

Particulate matter air pollution linked to increased cardiovascular disease death and disability worldwide

Review examines visual disturbances among Parkinson’s disease patients

High-level BPA exposure may affect male fertility

Cytochromes P450 enzymes exhibit unique soft-robotic properties, study reveals

Link found between vitamin D deficiency and metabolic abnormalities in children: New insights unveiled

Impact of age-related alterations in lipid metabolism on general health

Bone mineralization found to dampen metastatic progression of breast cancer

Childhood abuse can induce stress that changes neural networks and functions during growth

Study reports the first protein-based diagnostic signature to discriminate MIS-C from Kawasaki Disease and other common infections

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production