Metabolism News and Research

Latest Metabolism News and Research

Fruits and vegetables can increase or decrease the activity and toxicity of orally-administered drugs

Eating fruits and vegetables is essential to living a long and healthy life, yet research has shown they can cause dangerous interactions with medicines.

5 Oct 2005

Particular versions of the TGFb1 gene are largely responsible for how badly the illness affects patients' lungs

Subtle differences in other genes -- besides the defective gene known to cause the illness cystic fibrosis -- can significantly modify the inherited disease's severity, a large new multi-center national study has concluded.

5 Oct 2005

PET imaging with FDG represents one of the most promising tools for diagnosis of Alzheimer's

Positron emission tomography (PET) imaging--with the radiotracer fluorodeoxyglucose (FDG)--is a promising tool in detecting Alzheimer's disease in patients who have mild cognitive impairment (MCI), according to a study reported in the October issue of the Society of Nuclear Medicine's Journal of Nuclear Medicine.

5 Oct 2005

High blood glucose levels early in pregnancy deprive the embryo of oxygen

The babies of women with diabetes are two to five times more likely to develop birth defects than offspring of women without the disease.

4 Oct 2005

Largest systematic analysis of duplicated gene function to date

When Mother Nature creates an identical copy of a gene in an organism's genome, the duplicated copy is usually deleted, inactivated, or otherwise rendered nonfunctional in order to prevent genetic redundancy and to preserve biological homeostasis. In some cases, however, gene duplicates are maintained in a functional state.

4 Oct 2005

Researchers look at pharmacogenomics

When patients receive chemotherapy, 15 percent will have severe side effects while 85 percent will not - even though they're given the same relative dose.

28 Sep 2005

Experimental radioactive compound can show images of heart damage up to 30 hours after a brief interruption of blood flow and oxygen

The discovery may help physicians in emergency rooms and in their offices determine whether a patient's chest pain, which may have subsided hours earlier, is related to heart disease or something else, such as indigestion.

27 Sep 2005

Chronically high levels of insulin may block specific hormones that trigger energy release into the body

Their findings, which may point to new approaches to developing improved treatment options for the disease, are published in the journal Nature.

26 Sep 2005

Smoking may increase the risk of developing diabetes

The surprising finding emerged when researchers examined the relationship between smoking and diabetes among participants in a major national study, the Insulin Resistance Atherosclerosis Study (IRAS).

26 Sep 2005

New nutritional challenges in HIV/AIDS care have emerged

Nutritional therapy for HIV-infected patients is shifting focus. Drug treatments designed to combat the HIV virus have improved, decreasing some nutritional problems, while bringing others to light.

26 Sep 2005

Neurologix announces positive interim results of gene therapy clinical trial for patients with Parkinson's disease

Neurologix has announced positive interim results of its landmark gene therapy clinical trial for patients with Parkinson's disease. Neurologix's 12-patient, dose-escalating Phase I trial is the world's first study to use a viral vector (the non-pathogenic adeno-associated virus, or AAV) for the treatment of an adult neurological disease.

26 Sep 2005

Study clarifies insulin's role in blocking release of energy in patients with type II diabetes

Chronically high levels of insulin, as is found in many people with obesity and Type II diabetes, may block specific hormones that trigger energy release into the body, according to researchers at the University of California, San Diego (UCSD) School of Medicine.

22 Sep 2005

HDL cholesterol helps prevent blocked arteries and heart attack

Cardiology experts at Johns Hopkins have issued interim guidelines for physicians on how best to treat low levels of HDL cholesterol, the so-called good cholesterol, which helps keep arteries clear from the buildup of LDL cholesterol, the so-called bad cholesterol.

22 Sep 2005

Study reveals critical molecular events in the origin of fat cells

A new study reveals critical molecular events in the origin of fat cells. The findings are central to understanding chronic diseases, such as obesity and diabetes, as fat cells produce hormones critical for metabolic control, the researchers said.

21 Sep 2005

Low-dose aspirin might prevent the cardiovascular damage known to arise from use of the painkiller rofecoxib (Vioxx)

Their findings that a chemical imbalance might underlie such damage could also lead to the development of anti-inflammatory drugs without the adverse side effects, the researchers said.

20 Sep 2005

Molecular pathway in mice that makes prostate cells vulnerable to cancer-causing oxygen damage

Scientists from Maryland and New Jersey have identified a molecular pathway in mice that makes prostate cells vulnerable to cancer-causing oxygen damage.

19 Sep 2005

Double whammy of vitamin D and anti-inflammatory zaps prostate cancer cells

Scientists from Stanford University say they have discovered that vitamin D, known as the "sunshine vitamin,"can limit the growth of prostate cancer cells when combined with non-steroidal anti-inflammatory drugs.

6 Sep 2005

Metabolic Syndrome, a map of the cardiovascular damage

The metabolic syndrome (MS) is a cluster of metabolic abnormalities with abdominal obesity (increased waist circumference) at its centre. Although all forms of obesity have a negative impact on human health, metabolic syndrome describes a set of particularly adverse biochemical changes accompanying (abdominal) obesity.

5 Sep 2005

Naturally occurring peptide hormones - candidates for the treatment of cancer, sexual dysfunction, eating disorders

Chemists at the University of Arizona have developed modified versions of naturally occurring peptide hormones that could be key to novel treatments of a variety of diseases, including eating disorders (anorexia, obesity), diabetes, sexual dysfunction and skin cancer.

1 Sep 2005

Low doses of the active form of vitamin D and non-steroidal anti-inflammatory drugs form one-two punch against prostate cancer cells

Low doses of the active form of vitamin D and non-steroidal anti-inflammatory drugs, taken in combination, have been shown to act as a powerful one-two punch that knocks down the growth of prostate cancer cells.

1 Sep 2005

Metabolism News and Research

Latest Metabolism News and Research

Fruits and vegetables can increase or decrease the activity and toxicity of orally-administered drugs

Particular versions of the TGFb1 gene are largely responsible for how badly the illness affects patients' lungs

PET imaging with FDG represents one of the most promising tools for diagnosis of Alzheimer's

High blood glucose levels early in pregnancy deprive the embryo of oxygen

Largest systematic analysis of duplicated gene function to date

Researchers look at pharmacogenomics

Experimental radioactive compound can show images of heart damage up to 30 hours after a brief interruption of blood flow and oxygen

Chronically high levels of insulin may block specific hormones that trigger energy release into the body

Smoking may increase the risk of developing diabetes

New nutritional challenges in HIV/AIDS care have emerged

Neurologix announces positive interim results of gene therapy clinical trial for patients with Parkinson's disease

Study clarifies insulin's role in blocking release of energy in patients with type II diabetes

HDL cholesterol helps prevent blocked arteries and heart attack

Study reveals critical molecular events in the origin of fat cells

Low-dose aspirin might prevent the cardiovascular damage known to arise from use of the painkiller rofecoxib (Vioxx)

Molecular pathway in mice that makes prostate cells vulnerable to cancer-causing oxygen damage

Double whammy of vitamin D and anti-inflammatory zaps prostate cancer cells

Metabolic Syndrome, a map of the cardiovascular damage

Naturally occurring peptide hormones - candidates for the treatment of cancer, sexual dysfunction, eating disorders

Low doses of the active form of vitamin D and non-steroidal anti-inflammatory drugs form one-two punch against prostate cancer cells

Freezing Point Osmometry in Life Science Applications

Precision in every drop: Inside Hamilton’s syringe technology

Exploring the Future of Neuroscience Drug Discovery