Metabolism News and Research

Latest Metabolism News and Research

New three-organ system offers an animal-free alternative for pharmacokinetics research

Innovative organ-on-chip specialist Dynamic42 and ESQlabs, experts in digital life sciences solutions, have successfully developed a three-organ system, in close collaboration with Consumer Health Division of Bayer, and the Placenta Lab at Jena University Hospital.

2 Mar 2025

Intermittent fasting cuts heart attack risk by preventing dangerous blood clots

Intermittent fasting may reduce the risk of blood clots and cardiovascular disease by inhibiting platelet activation.

2 Mar 2025

TFE3 activation shows promise for counteracting Parkinson's disease pathology

This recent study highlights the neuroprotective potential of TFE3, a transcription factor that plays a pivotal role in counteracting key pathological mechanisms associated with Parkinson's disease (PD).

2 Mar 2025

Researchers uncover how brain tumors reprogram neutrophils to hinder cancer treatment

The lab of Filippo Veglia, Ph.D., at The Wistar Institute has discovered a previously unknown mechanism for how aggressive brain cancers reprogram immune system cells from fighting cancer to enabling further tumor growth.

2 Mar 2025

Scientists develop fenugreek-based nanoparticles to enhance diabetes drug effectiveness

Researchers explored L-arginine-loaded lipid nanoparticles from fenugreek seed oil, finding they enhance drug stability and bioavailability, showing promise for diabetes treatment.

2 Mar 2025

Understanding obesity in pets and its health risks

Your 8-year-old chocolate Lab is putting on weight, and you know she should probably lose a pound or two. But when she looks at you pleadingly with those big brown eyes, how can you resist handing out just one more treat?

28 Feb 2025

Ursodeoxycholic acid shows promise in treating drug-induced liver injury

Drug-induced liver injury (DILI) is a significant concern in clinical practice, arising from medications, herbs, and dietary supplements.

28 Feb 2025

Study demonstrates successful gene therapy for maple syrup urine disease

A study led by UMass Chan researchers demonstrated that a gene therapy to correct a mutation that causes maple syrup urine disease (MSUD) prevented newborn death, normalized growth, restored coordinated expression of the affected genes and stabilized biomarkers in a calf as well as in mice.

28 Feb 2025

Lactylation in the heart reveals key insights into cardiac regeneration

This study is led by Dr. Xiaodong Luan (Institute of Clinical Medicine, Peking Union Medical College Hospital), Dr. Shuyang Zhang (Department of Rare Diseases, Peking Union Medical College Hospital) and Dr. He Huang (Shanghai Institute of Materia Medica, Chinese Academy of Sciences).

28 Feb 2025

Grapefruit juice and its effects on prescription drugs

Grapefruit juice can interfere with how certain medications work by affecting drug metabolism and absorption, leading to either increased side effects or reduced effectiveness. The FDA requires warnings on some drugs due to these interactions, making it essential to check labels and consult healthcare providers.

28 Feb 2025

Review sheds light on the mechanistic role of long non-coding RNAs in liver disease

Metabolic dysfunction-associated steatotic liver disease (MASLD), formerly known as non-alcoholic fatty liver disease (NAFLD), is a global health challenge, affecting nearly 30% of adults worldwide.

28 Feb 2025

Researchers discover key blood molecules impacting child development

McMaster University researchers have identified small molecules in the blood that may impact early childhood development, showing how dietary exposures, early life experiences, and gut health can influence a child's growth and cognitive milestones.

28 Feb 2025

Understanding the impact of SLC transporters on liver disease progression

Hepatic steatosis, often triggered by non-alcoholic fatty liver disease (NAFLD), is a leading cause of liver dysfunction globally, affecting approximately 30% of the population.

28 Feb 2025

The brain-gut microbiota axis: Impact on mental health & potential treatment avenues

To be decided by the editor

From Atlantia Clinical Trials 28 Feb 2025

New discovery sheds light on energy crisis in children with TANGO2 deficiency

Researchers studying a protein linked to a rare, severe disease have made a discovery that sheds light on how cells meet their energy needs during a severe metabolic crisis.

28 Feb 2025

Do sugar substitutes really help? New research reveals their impact on metabolism and gut health

Low and no-calorie sweeteners (LNCSs) help reduce sugar intake, but their long-term effects on metabolism, gut health, and insulin response remain under investigation. Ongoing research explores their safety, effectiveness, and regulatory landscape.

27 Feb 2025

Artificial sweeteners may reduce metformin’s effectiveness in weight and glucose control

Drinking artificially sweetened beverages may reduce metformin’s effectiveness in young patients with obesity and prediabetes, but a larger study is needed to confirm these findings.

27 Feb 2025

Scientists uncover how a sugar shield in brain blood vessels protects against aging and disease

Researchers reveal that the loss of mucin-type O-glycosylation in the brain endothelial glycocalyx weakens the blood-brain barrier, leading to increased permeability, neuroinflammation, and cognitive decline in aging and neurodegenerative diseases.

27 Feb 2025

Macrophages use bacteria to build vital nutrients and control inflammation

Immune cells that eat bacteria in the body don't stash them in specialized compartments as once thought, but turn them into critical nutrients that build proteins, create energy and keep the cells alive, according to a new study from scientists at the University of Colorado Anschutz Medical Campus.

27 Feb 2025

Microphysiological systems in drug discovery

NewsMedical speaks with CN Bio about the translatability between in vitro organ-on-a-chip (OOC) models, microphysiological systems, and their in vivo counterparts.

From CN Bio Innovations Ltd 26 Feb 2025

Metabolism News and Research

Latest Metabolism News and Research

New three-organ system offers an animal-free alternative for pharmacokinetics research

Intermittent fasting cuts heart attack risk by preventing dangerous blood clots

TFE3 activation shows promise for counteracting Parkinson's disease pathology

Researchers uncover how brain tumors reprogram neutrophils to hinder cancer treatment

Scientists develop fenugreek-based nanoparticles to enhance diabetes drug effectiveness

Understanding obesity in pets and its health risks

Ursodeoxycholic acid shows promise in treating drug-induced liver injury

Study demonstrates successful gene therapy for maple syrup urine disease

Lactylation in the heart reveals key insights into cardiac regeneration

Grapefruit juice and its effects on prescription drugs

Review sheds light on the mechanistic role of long non-coding RNAs in liver disease

Researchers discover key blood molecules impacting child development

Understanding the impact of SLC transporters on liver disease progression

The brain-gut microbiota axis: Impact on mental health & potential treatment avenues

New discovery sheds light on energy crisis in children with TANGO2 deficiency

Do sugar substitutes really help? New research reveals their impact on metabolism and gut health

Artificial sweeteners may reduce metformin’s effectiveness in weight and glucose control

Scientists uncover how a sugar shield in brain blood vessels protects against aging and disease

Macrophages use bacteria to build vital nutrients and control inflammation

Microphysiological systems in drug discovery

The evolution of OCT for retinal imaging and disease intervention

Supercharging Next-Gen Antibody Discovery with AI and High-Throughput Experimentation

Prof. Dr. Kristina Kusche-Vihrog