Metabolism News and Research

Latest Metabolism News and Research

An emerging target for chronic kidney disease treatment - DNA-PKcs

A recent Nature Communications study suggested that DNA-PKcs could be a potential target for treating chronic kidney disease.

15 Mar 2023

Long-acting GIPRA inhibits feeding and lowers body weight in mice with diet-induced obesity

The hormone glucose-dependent insulinotropic polypeptide (GIP) is considered obesogenic. In contrast, GIP receptor agonists (GIPRAs) have shown reduced feeding and body weight in an obese mouse model. Therefore, the precise effects exerted by GIP and GIPRAs remain elusive.

14 Mar 2023

Long-term antibiotic therapy for adolescent acne can affect liver metabolism and promote adiposity

A growing body of evidence is showing that the healthy gut microbiome – a community of microorganisms that live together in the gut – influences many aspects of human growth and development, especially during adolescence.

14 Mar 2023

Insufficient sleep results in decreased antibody response to vaccination

In reviewing data from previous studies, a team lead by researchers at the University of Chicago and the French National Institute of Health and Medical Research (Inserm) found that individuals who had fewer than six hours of sleep per night in the days surrounding vaccination had a blunted antibody response.

14 Mar 2023

Understanding how cells adjust in real time to withstand stresses on our health

Every minute of every day, our body adapts to meet the needs of each moment. When we binge on carbs, exercise, or become sick, chemical reactions inside our cells switch on, slow down, or shift strategy so that we have the energy and strength we need.

14 Mar 2023

The development of the pediatric oral resistome and its role in dental caries

Researchers performed a genomic investigation of oral resistome development, i.e., of genes that confer antimicrobial resistance.

14 Mar 2023

Distinct microbial profile present in intrahepatic cholestasis of pregnancy patients

Researchers assessed the impact of the gut microbiome on the host's bile acid metabolism and intrahepatic cholestasis of pregnancy (ICP).

14 Mar 2023

Hypothalamic inflammation and obesity, study suggests a pathological mechanism

In a recent review published in the European Journal of Endocrinology, researchers discussed current research on the relationship between human obesity and inflammation of the hypothalamus.

14 Mar 2023

Hyperinflammation triggers long COVID headaches

Researchers characterize the immunological and metabolic alterations involved in chronic headache onset during post-acute sequelae of COVID-19.

13 Mar 2023

New study focuses on genetic diversity of E. coli bacteria in hospitalized patients

The human intestine is an environment inhabited by many bacteria and other microorganisms collectively known as the gut microbiome, gut microbiota or intestinal flora. In most people, it contributes to wellness.

13 Mar 2023

Injectable peptide used for type 2 diabetes shows potential for treating 'blinding' IIH headaches

Patients with 'blinding' headaches known as Idiopathic Intercranial Hypertension could be treated with an injectable peptide used for type 2 diabetes, a new trial has found.

13 Mar 2023

Insulin deficiency leads to reduced pancreas size in type 1 diabetes

Individuals with Type 1 diabetes have a smaller pancreas than people without diabetes. This is surprising because insulin-producing beta cells account for just a small fraction of the pancreas, so the loss of beta cells in Type 1 diabetes would not be expected to reduce pancreas size.

10 Mar 2023

Light exposure before bedtime may be a easily modifiable risk factor of gestational diabetes

Pregnant persons should dim the lights in their home and turn off or at least dim their screens (computer monitors and smartphones) a few hours before bedtime to reduce the risk of gestational diabetes mellitus, a new Northwestern Medicine study shows.

10 Mar 2023

Dietary polyphenol intake reduces risk of metabolic syndrome

Researchers investigate the relationship between dietary polyphenol intake and metabolic syndrome.

10 Mar 2023

Study explores solutions for advancing health equity through diversifying clinical trials

Despite racial and ethnic minority groups making up nearly half of the United States population, underrepresentation in clinical trials remains a critical challenge.

9 Mar 2023

A small protein could provide a revolutionary approach to tackling obesity-related diseases

Research published today shows that a peptide (small protein) called PEPITEM could provide a revolutionary approach to reducing the risk of type 2 diabetes and other obesity-related diseases such as hepatic steatosis (fatty liver).

9 Mar 2023

University of Utah and Tikkunlev partner to bring heart failure gene therapy innovation to the clinic

The University of Utah, one of the nation's leading research universities, and TikkunLev Therapeutics, a gene therapy company, have announced a new partnership to accelerate an innovative heart-failure gene therapy.

8 Mar 2023

Discovery could lead to effective treatments for acute alcohol intoxication

A shot of a liver-produced hormone called FGF21 sobered up mice that had passed out from alcohol, allowing them to regain consciousness and coordination much faster than those that didn't receive this treatment, UT Southwestern researchers report in a new study.

8 Mar 2023

Study finds no association between gout and neurodegenerative diseases in the general population

A study published in Scientific Reports highlights that gout can increase the risk of Alzheimer’s disease and Parkinson’s disease in younger or overweight individuals. The study was conducted in a representative Korean population.

8 Mar 2023

The importance of ketones from a clinical and medical perspective

In this interview, News-Medical talks to Marcin Pacek, senior director of medical and scientific affairs in Europe for Nova Biomedical, about the importance of ketones in a medical and clinical setting.

From Nova Biomedical 8 Mar 2023

Metabolism News and Research

Latest Metabolism News and Research

An emerging target for chronic kidney disease treatment - DNA-PKcs

Long-acting GIPRA inhibits feeding and lowers body weight in mice with diet-induced obesity

Long-term antibiotic therapy for adolescent acne can affect liver metabolism and promote adiposity

Insufficient sleep results in decreased antibody response to vaccination

Understanding how cells adjust in real time to withstand stresses on our health

The development of the pediatric oral resistome and its role in dental caries

Distinct microbial profile present in intrahepatic cholestasis of pregnancy patients

Hypothalamic inflammation and obesity, study suggests a pathological mechanism

Hyperinflammation triggers long COVID headaches

New study focuses on genetic diversity of E. coli bacteria in hospitalized patients

Injectable peptide used for type 2 diabetes shows potential for treating 'blinding' IIH headaches

Insulin deficiency leads to reduced pancreas size in type 1 diabetes

Light exposure before bedtime may be a easily modifiable risk factor of gestational diabetes

Dietary polyphenol intake reduces risk of metabolic syndrome

Study explores solutions for advancing health equity through diversifying clinical trials

A small protein could provide a revolutionary approach to tackling obesity-related diseases

University of Utah and Tikkunlev partner to bring heart failure gene therapy innovation to the clinic

Discovery could lead to effective treatments for acute alcohol intoxication

Study finds no association between gout and neurodegenerative diseases in the general population

The importance of ketones from a clinical and medical perspective

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production