Morphine News and Research

Latest Morphine News and Research

Discovery of pain paradox paves way to new methods of pain control

A natural substance known to activate pain in the central nervous system has been found to have the opposite effect in other parts of the body, potentially paving the way to new methods of pain control.

28 Jul 2016

Buprenorphine implants could be effective option to treat adults with opioid dependence

While buprenorphine has long been used to treat adults with opioid dependence, its efficacy can be hindered by lack of adherence to daily, sublingual (beneath the tongue) doses of the medication.

19 Jul 2016

New opioid use among older adults with COPD linked to increased risk for respiratory-related death

Older adults with chronic obstructive pulmonary disease who start using opioids have a more than two-fold higher risk of dying from a respiratory-related complication compared to non-opioid users, St. Michael's Hospital researchers have found.

14 Jul 2016

Programs to prevent prescription drug misuse may be underused, study reveals

Misuse of prescription pain medications remains a major public health problem -- but programs to prevent it may be underused, according to a study in the July issue of the Journal of Studies on Alcohol and Drugs.

29 Jun 2016

Study identifies persistent opioid use in some patients after knee or hip replacement

Many patients undergoing hip or knee replacement are still taking prescription opioid pain medications up to six months after surgery, reports a study in PAIN, the official publication of the International Association for the Study of Pain.

1 Jun 2016

Short-term use of opioids implicated in protracted pain, new study finds

Painkillers such as morphine, oxycodone and methadone could actually prolong and increase pain even after only a few days’ use, according to research conducted on rats by scientists at the University of Colorado Boulder in the US.

31 May 2016

Brief opioid exposure can cause increase in chronic pain

The dark side of painkillers - their dramatic increase in use and ability to trigger abuse, addiction and thousands of fatal overdoses annually in the United States is in the news virtually every day.

31 May 2016

Researchers find Aspergillus as interesting target for discovery of novel drugs

The fungus Aspergillus fumigatus produces a group of previously unknown natural products. With reference to plant isoquinoline alkaloids, these substances have been named fumisoquins.

28 May 2016

Opioids could be dangerous, deadly at high doses

Most people know that heroin is a dangerous drug, but its cousins, the legal, pharmaceutical opioids, such as codeine or hydrocodone, must be safe, right?Not so fast.Opioids—which include the illegal drug heroin as well as prescription medications, including hydrocodone (such as Vicodin), oxycodone (such as OxyContin and Percocet), morphine and codeine—can be dangerous, even deadly, at high doses.

31 Mar 2016

FDA announces required class-wide safety labeling changes for IR opioid pain medications

In a continuing effort to educate prescribers and patients about the potential risks related to opioid use, the U.S. Food and Drug Administration today announced required class-wide safety labeling changes for immediate-release (IR) opioid pain medications. Among the changes, the FDA is requiring a new boxed warning about the serious risks of misuse, abuse, addiction, overdose and death.

23 Mar 2016

New reference guide can help HIV care providers treat chronic pain

Recent studies suggest many individuals with HIV have chronic pain. Estimates range from 39 percent all the way to 85 percent. Chronic pain is an important comorbid condition in individuals with HIV, as it is common and causes substantial disability.

22 Mar 2016

Promising therapeutic strategy for relieving neuropathic pain

A specific molecule involved in maintaining pain after a nerve injury has been identified and blocked in mice by Hiroshima University researchers. These results reveal a promising therapeutic strategy for treating neuropathic pain.

1 Mar 2016

Japanese bioengineers tweak E. coli genes to pump out morphine precursor

A common gut microbe could soon be offering us pain relief. Japanese bioengineers have tweaked Escherichia coli genes so that they pump out thebaine, a morphine precursor that can be modified to make painkillers. The genetically modified E. coli produces 300 times more thebaine with minimal risk of unregulated use compared to a recently developed method involving yeast.

26 Feb 2016

New vaccine strategy may curb addiction, prevent fatal overdoses

With use of synthetic opioid "designer drugs" on the rise, scientists from The Scripps Research Institute have a new strategy to curb addiction and even prevent fatal overdoses.

17 Feb 2016

Researchers develop new painkiller as strong as morphine but not addictive

Researchers at Tulane University and Southeast Louisiana Veterans Health Care System have developed a painkiller that is as strong as morphine but isn't likely to be addictive and with fewer side effects, according to a new study in the journal Neuropharmacology.

29 Jan 2016

Educational programs, new clinic policies could significantly reduce level of opioid medication

A recent study showed that medical provider training, new clinic policies and efforts to "taper" opioid use for pain treatment could significantly reduce the level of opioid medication that patients used -- a limited but positive step for a nation enmeshed in opioid use, abuse and overdose deaths.

27 Jan 2016

Opioid medication does not improve physical function in patients with neuropathic pain

Opioids such as morphine, codeine and Tylenol 3 can be effective for treating pain, however, a new University of Alberta study finds that patients with neuropathic pain taking opioids report no improvements in physical functioning compared to those who were not prescribed opioids.

25 Jan 2016

Long-term use of opioids increases risk of new-onset depression

Opioids may cause short-term improvement in mood, but long-term use imposes risk of new-onset depression, a Saint Louis University study shows.

13 Jan 2016

Egalet submits NDA for ARYMO ER (morphine sulfate) extended-release tablets

Egalet Corporation, a fully integrated specialty pharmaceutical company focused on developing, manufacturing and commercializing innovative treatments for pain and other conditions, announced the company has submitted a new drug application (NDA) for ARYMO ER (morphine sulfate) extended-release tablets for the management of pain severe enough to require daily, around-the-clock opioid treatment and for which alternative treatments are inadequate.

15 Dec 2015

Egalet, Teva sign agreement to commercialize SPRIX Nasal Spray in Israel, Gaza and the West Bank

Egalet Corporation, a fully integrated specialty pharmaceutical company focused on developing, manufacturing and commercializing innovative treatments for pain and other conditions, today announced a collaboration agreement with Teva Pharmaceutical Industries Ltd., a leading global pharmaceutical company.

14 Dec 2015

Morphine News and Research

Latest Morphine News and Research

Discovery of pain paradox paves way to new methods of pain control

Buprenorphine implants could be effective option to treat adults with opioid dependence

New opioid use among older adults with COPD linked to increased risk for respiratory-related death

Programs to prevent prescription drug misuse may be underused, study reveals

Study identifies persistent opioid use in some patients after knee or hip replacement

Short-term use of opioids implicated in protracted pain, new study finds

Brief opioid exposure can cause increase in chronic pain

Researchers find Aspergillus as interesting target for discovery of novel drugs

Opioids could be dangerous, deadly at high doses

FDA announces required class-wide safety labeling changes for IR opioid pain medications

New reference guide can help HIV care providers treat chronic pain

Promising therapeutic strategy for relieving neuropathic pain

Japanese bioengineers tweak E. coli genes to pump out morphine precursor

New vaccine strategy may curb addiction, prevent fatal overdoses

Researchers develop new painkiller as strong as morphine but not addictive

Educational programs, new clinic policies could significantly reduce level of opioid medication

Opioid medication does not improve physical function in patients with neuropathic pain

Long-term use of opioids increases risk of new-onset depression

Egalet submits NDA for ARYMO ER (morphine sulfate) extended-release tablets

Egalet, Teva sign agreement to commercialize SPRIX Nasal Spray in Israel, Gaza and the West Bank

Innovation in neuroscience drug discovery - eBook eBook

The evolution of OCT for retinal imaging and disease intervention

Supercharging Next-Gen Antibody Discovery with AI and High-Throughput Experimentation

Prof. Dr. Kristina Kusche-Vihrog

Morphine News and Research

Latest Morphine News and Research

Innovation in neuroscience drug discovery - eBook eBook

The evolution of OCT for retinal imaging and disease intervention

Supercharging Next-Gen Antibody Discovery with AI and High-Throughput Experimentation

Prof. Dr. Kristina Kusche-Vihrog

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