Nervous System News and Research

Latest Nervous System News and Research

Insilico Medicine's pan-TEAD inhibitor ISM6331 receives FDA IND clearance for mesothelioma treatment

Insilico Medicine ("Insilico"), a clinical-stage generative artificial intelligence (AI)-driven biotechnology company, today announced ISM6331, potential best-in-class pan-TEAD inhibitor, has received the U.S. Food and Drug Administration (FDA) Investigational New Drug (IND) clearance for the treatment of mesothelioma, following the grant of Orphan Drug Designation (ODD) in June 2024. It brings the total number of IND-approved molecules of Insilico to nine.

8 Aug 2024

C-Path supports innovative ALS, neurodegenerative disease research with new grant

Critical Path Institute's (C-Path) Translational Therapeutics Accelerator (TRxA) announced today a new research grant awarded to Daniela C. Zarnescu, Ph.D., Professor of Cellular and Molecular Physiology at Penn State University College of Medicine, in collaboration with Jon Njardarson, Ph.D., Professor at the University of Arizona.

8 Aug 2024

Study suggests lower dementia risk for people with Parkinson's

There's some good news for people with Parkinson's disease: The risk of developing dementia may be lower than previously thought, or dementia may occur later in the course of the disease than previously reported, according to a study published in the August 7, 2024, online issue of Neurology, the medical journal of the American Academy of Neurology.

7 Aug 2024

How C. elegans uses smell to preemptively guard against pathogen attacks

Many organisms react to the smell of deadly pathogens by reflexively avoiding them. But a recent study from the University of California, Berkeley, shows that the nematode C. elegans also reacts to the odor of pathogenic bacteria by preparing its intestinal cells to withstand a potential onslaught.

7 Aug 2024

Sensory nerves drive breast cancer growth and spread, study reveals

Cancer doesn't grow in a vacuum-;each tumor grows in a particular microenvironment within the body and spreads through a tangled web of vasculature and nerves.

7 Aug 2024

Therapeutic targets that impact both cardiac and cerebral functions in CNS neurological disorders

Recent advancements highlight the intricate interplay between the heart and brain, underscoring their profound influence on each other, especially concerning central nervous system (CNS) neurological disorders.

7 Aug 2024

NUS study finds 5-HTP enhances sleep quality and gut health in older adults

National University of Singapore (NUS) nutritionists have found that 5-Hydroxytryptophan (5-HTP) supplementation can improve sleep quality in Singaporean older adults, particularly in individuals with poor sleep patterns, and manage their gut microbiome composition.

7 Aug 2024

Study uncovers roles of certain brain cells in Alzheimer's plaque formation

A study in Nature Neuroscience found that both neurons and oligodendrocytes contribute to amyloid-β plaque burden in Alzheimer's disease, highlighting new therapeutic targets.

7 Aug 2024

Breakthrough MS drug uses green mamba venom discovery to promote myelin repair

Ten years of work, and a little help from the green mamba snake, has resulted in a promising new drug that is already being tested in clinical trials.

5 Aug 2024

FDA approves AChEI ALPHA-1062 for Alzheimer’s disease treatment

On July 29, 2024, the U.S. FDA approved Alpha Cognition Inc.'s ALPHA-1062 (Zunveyl®), an Acetylcholinesterase (AChE) inhibitor, for treating mild-to-moderate Alzheimer’s disease.

From Sino Biological Inc. 5 Aug 2024

Cholesterol imbalance linked to neurodegeneration, study suggests potential strategies for intervention

Research highlights how cholesterol imbalances in the brain contribute to neurodegenerative diseases like Alzheimer's, Huntington's, and Parkinson's, suggesting targeted therapeutic interventions.

5 Aug 2024

Active immune cells discovered in brain's cranial bone marrow fighting glioblastomas

A study uncovers the presence and activity of immune cells in glioblastoma, revealing new insights into brain tumor immunology and potential treatment avenues.

4 Aug 2024

Vanderbilt researchers illuminate white matter signals in the spinal cord

Injuries, infection and inflammatory diseases that damage the spinal cord can lead to intractable pain and disability. Some degree of recovery may be possible. The question is, how best to stimulate the regrowth and healing of damaged nerves.

2 Aug 2024

Study elucidates mechanisms behind G protein selectivity and efficacy in adenosine A2A receptor

In a groundbreaking study, a multinational research team led by Dr. Adnan Sljoka (RIKEN) and Prof. Akio Kitao (Tokyo Tech), in collaboration with Prof. Scott Prosser (University of Toronto), has carried out experimental and computational studies to elucidate the mechanisms behind G protein selectivity and efficacy in the human adenosine A2A receptor (A2AR).

1 Aug 2024

High diastolic blood pressure linked to increased migraine risk in women

Having high blood pressure, specifically high diastolic blood pressure, was linked to a slightly higher odds of ever having migraine in female participants, according to a new study published in the July 31, 2024, online issue of Neurology, the medical journal of the American Academy of Neurology.

31 Jul 2024

Nervous System News and Research

Latest Nervous System News and Research

Insilico Medicine's pan-TEAD inhibitor ISM6331 receives FDA IND clearance for mesothelioma treatment

C-Path supports innovative ALS, neurodegenerative disease research with new grant

Study suggests lower dementia risk for people with Parkinson's

How C. elegans uses smell to preemptively guard against pathogen attacks

Sensory nerves drive breast cancer growth and spread, study reveals

Therapeutic targets that impact both cardiac and cerebral functions in CNS neurological disorders

NUS study finds 5-HTP enhances sleep quality and gut health in older adults

Study uncovers roles of certain brain cells in Alzheimer's plaque formation

Breakthrough MS drug uses green mamba venom discovery to promote myelin repair

FDA approves AChEI ALPHA-1062 for Alzheimer’s disease treatment

Cholesterol imbalance linked to neurodegeneration, study suggests potential strategies for intervention

Active immune cells discovered in brain's cranial bone marrow fighting glioblastomas

Vanderbilt researchers illuminate white matter signals in the spinal cord

Study elucidates mechanisms behind G protein selectivity and efficacy in adenosine A2A receptor

High diastolic blood pressure linked to increased migraine risk in women

Powerful visualization technologies offer new insight into understanding muscle contraction in humans

Propofol shows potential for treating epilepsy and neurological disorders

Wearable, non-invasive device can measure activity in human cervical nerves in clinical settings

New study reveals how colorectal cancer cells establish liver metastases

Insilico Medicine unveils Science42:DORA to streamline academic writing and research

Precision in every drop: Inside Hamilton’s syringe technology

Exploring the Future of Neuroscience Drug Discovery

Genomic conservation in Thailand's mangroves

Nervous System News and Research

Latest Nervous System News and Research

Precision in every drop: Inside Hamilton’s syringe technology

Exploring the Future of Neuroscience Drug Discovery

Genomic conservation in Thailand's mangroves

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