Nervous System News and Research

Latest Nervous System News and Research

Alkermes announces results from phase 3 clinical trial of aripiprazole lauroxil in patients with schizophrenia

Alkermes plc today announced positive topline results from a randomized, double-blind, placebo-controlled phase 3 clinical trial of aripiprazole lauroxil in patients with schizophrenia. Patients treated once monthly with either 441 mg or 882 mg of aripiprazole lauroxil demonstrated statistically significant reductions from baseline in Positive and Negative Syndrome Scale (PANSS) total scores at week 12, compared to placebo (p<0.001 aripiprazole lauroxil 441 mg, p<0.001 aripiprazole lauroxil 882 mg), which was the prespecified primary endpoint in the study. Based on the positive results from this phase 3 study, Alkermes plans to submit a New Drug Application (NDA) to the U.S. Food and Drug Administration (FDA) in the third quarter of 2014.

8 Apr 2014

Novartis Institute researcher receives second annual Andrew Carnegie Prize in Mind and Brain Sciences

Carnegie Mellon University will award the second annual Andrew Carnegie Prize in Mind and Brain Sciences to Ricardo Dolmetsch, global head of neuroscience at the Novartis Institute for Biomedical Research.

8 Apr 2014

Researchers identify potential treatment targets for incurable form of pediatric brain cancer

Researchers from the University of Toronto's Department of Laboratory Medicine and Pathobiology (LMP) have defined potential treatment targets for a previously incurable form of pediatric brain cancer called Diffuse Intrinsic Pontine Glioma (DIPG).

8 Apr 2014

Helium ion radiotherapy provides hope for improved, accurate radiation treatment for young cancer patients

For the first time, researchers have been able to demonstrate that the use of helium ions in radiation therapy could provide accurate treatment to tumours while helping to spare healthy organs.

7 Apr 2014

Neuroinflammation levels higher in patients with chronic fatigue syndrome

Researchers at the RIKEN Center for Life Science Technologies, in collaboration with Osaka City University and Kansai University of Welfare Sciences, have used functional PET imaging to show that levels of neuroinflammation, or inflammation of the nervous system, are higher in patients with chronic fatigue syndrome than in healthy people.

4 Apr 2014

Harvard stem cell scientists discover potential treatment for amyotrophic lateral sclerosis

Harvard stem cell scientists have discovered that a recently approved medication for epilepsy may possibly be a meaningful treatment for amyotrophic lateral sclerosis (ALS)-Lou Gehrig's disease, a uniformly fatal neurodegenerative disorder. The researchers are now collaborating with Massachusetts General Hospital to design an initial clinical trial testing the safety of the treatment in ALS patients.

4 Apr 2014

FDA clears Omeros' OMS721 IND for inhibition of complement‑mediated TMAs

Omeros Corporation today announced that its Investigational New Drug Application (IND) to evaluate OMS721 for the inhibition of complement‑mediated thrombotic microangiopathies (TMAs) has been cleared by the U.S. Food and Drug Administration.

3 Apr 2014

Study sheds light on brain mechanisms that make schizophrenia patients misinterpret what they see

People with schizophrenia often misinterpret what they see and experience in the world. New research provides insight into the brain mechanisms that might be responsible for this misinterpretation.

3 Apr 2014

Young adults participated in cardio fitness activities may preserve memory, thinking skills in middle age

Young adults who run or participate in other cardio fitness activities may preserve their memory and thinking skills in middle age, according to a new study published in the April 2, 2014, online issue of Neurology®, the medical journal of the American Academy of Neurology. Middle age was defined as ages 43 to 55.

3 Apr 2014

Expert in gene therapy joins The Children's Hospital of Philadelphia

Beverly L. Davidson, Ph.D., a nationally prominent expert in gene therapy, is joining The Children's Hospital of Philadelphia (CHOP) today.

2 Apr 2014

Uric acid in urine generates potentially hazardous in swimming pools by interacting with chlorine

A new study shows how uric acid in urine generates potentially hazardous "volatile disinfection byproducts" in swimming pools by interacting with chlorine, and researchers are advising swimmers to observe "improved hygiene habits.

2 Apr 2014

Scientists present protein that facilitates control of nerve cells by light

Networked nerve cells are the control center of organisms. In a nematode, 300 nerve cells are sufficient to initiate complex behavior. To understand the properties of the networks, re-searchers switch cells on and off with light and observe the resulting behavior of the organism.

2 Apr 2014

New neuromonitoring method prevents malpositioning of pedicle screws during thoracic spine surgery

Researchers from Syracuse, New York, report a new, highly accurate, neuromonitoring method that can be used during thoracic spine surgery to prevent malpositioning of pedicle screws such that they enter the spinal canal and possibly cause postoperative neurological impairment.

2 Apr 2014

Study shows link between breast-feeding and risk of child developing obesity

Many studies have focused on the influence of breast-feeding on child health. From analysis of data from the ELANCE cohort, Marie Fran-oise Rolland-Cachera, former researcher at Inserm and her co-workers in the Nutritional Epidemiology Research Team (EREN) have shown that breast-feeding has a protective effect on the risk of obesity at 20 years of age.

2 Apr 2014

EMD Serono collaborates with Pfizer and Broad Institute

EMD Serono, a subsidiary of Merck KGaA, Darmstadt, Germany, today announced they have signed a research agreement with Pfizer Inc. and the Broad Institute in Cambridge, Massachusetts, U.S. The collaboration is focused on the genomic profiling of Systemic Lupus Erythematosus (SLE) and Lupus Nephritis (LN) patients.

1 Apr 2014

Researchers identify possible mechanism for re-growing damaged nerve fibres in central nervous system

A new discovery suggests it could one day be possible to chemically reprogram and repair damaged nerves after spinal cord injury or brain trauma.

1 Apr 2014

Early rehabilitation improves neurofunctional outcome after surgery in children with spinal tumors

In children, primary spinal tumors comprise 4% of all tumors from the central nervous system. Spinal tumors can present with a variety of clinical signs and symptoms in children such as pain followed by motor regression, gait disturbance, sphincter dysfunction, sensory symptoms, torticollis, and kyphoscoliosis.

1 Apr 2014

Nervous System News and Research

Latest Nervous System News and Research

Alkermes announces results from phase 3 clinical trial of aripiprazole lauroxil in patients with schizophrenia

Novartis Institute researcher receives second annual Andrew Carnegie Prize in Mind and Brain Sciences

Researchers identify potential treatment targets for incurable form of pediatric brain cancer

Helium ion radiotherapy provides hope for improved, accurate radiation treatment for young cancer patients

Neuroinflammation levels higher in patients with chronic fatigue syndrome

Harvard stem cell scientists discover potential treatment for amyotrophic lateral sclerosis

FDA clears Omeros' OMS721 IND for inhibition of complement‑mediated TMAs

Study sheds light on brain mechanisms that make schizophrenia patients misinterpret what they see

Young adults participated in cardio fitness activities may preserve memory, thinking skills in middle age

Expert in gene therapy joins The Children's Hospital of Philadelphia

Uric acid in urine generates potentially hazardous in swimming pools by interacting with chlorine

Scientists present protein that facilitates control of nerve cells by light

New neuromonitoring method prevents malpositioning of pedicle screws during thoracic spine surgery

Study shows link between breast-feeding and risk of child developing obesity

EMD Serono collaborates with Pfizer and Broad Institute

Researchers identify possible mechanism for re-growing damaged nerve fibres in central nervous system

Early rehabilitation improves neurofunctional outcome after surgery in children with spinal tumors

e-Therapeutics announces interim results from ETS2101 phase Ia trial for advanced solid tumours

Otsuka inks agreement with Eisai to acquire rights to hematological cancer treatment Dacogen

Forest Laboratories, Richter report positive results from cariprazine Phase IIb trial for bipolar depression

Transforming Cardiovascular Care: Insights from Mina Makar at AstraZeneca

Clue's CEO Rhiannon White on the Future of Femtech and PCOS

Freezing Point Osmometry in Life Science Applications

Nervous System News and Research

Latest Nervous System News and Research

Transforming Cardiovascular Care: Insights from Mina Makar at AstraZeneca

Clue's CEO Rhiannon White on the Future of Femtech and PCOS

Freezing Point Osmometry in Life Science Applications

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