Nervous System News and Research

Latest Nervous System News and Research

Jazz Pharmaceuticals' Versacloz now commercially available in the U.S. for schizophrenia

Jazz Pharmaceuticals plc today announced U.S. commercial availability of Versacloz (clozapine, USP) oral suspension, the first and only oral suspension clozapine for severely ill treatment-resistant schizophrenia patients or those at risk of recurrent suicidal behavior with schizophrenia or schizoaffective disorder.

11 Feb 2014

New approach for reducing levels of toxic protein fragments associated with Huntington's disease

An innovative therapeutic strategy for reducing the levels of toxic protein fragments associated with Huntington's disease uses a new approach called exon skipping to remove the disease-causing component of the essential protein, huntingtin.

11 Feb 2014

Omeros announces additional positive data from OMS824 Phase 1 program

Omeros Corporation today announced additional positive data from its Phase 1 program for OMS824, the lead compound in Omeros' phosphodiesterase 10 (PDE10) program. This clinical trial evaluated the extent to which OMS824 binds to PDE10, an enzyme expressed in the region of the brain that has been linked to a wide range of diseases that affect cognition. In the latest cohort enrolled in this trial, OMS824 achieved a high of approximately 70‑percent engagement at PDE10 without evidence of extrapyramidal symptoms (EPS).

11 Feb 2014

Transcendental meditation technique shows significant reduction in PTSD in just 10 days

African civilians in war-torn countries have experienced the threat of violence or death, and many have witnessed the abuse, torture, rape and even murder of loved ones. Many Congolese living in Ugandan refugee camps are suffering from severe posttraumatic stress disorder (PTSD).

11 Feb 2014

Long-distance signaling molecules tell brain to produce anti-viral interferon

The brain contains a defense system that prevents at least two unrelated viruses-and possibly many more-from invading the brain at large. The research is published online ahead of print in the Journal of Virology.

11 Feb 2014

Researchers shed new light on pain associated with bacterial infections

Components in the outer wall of bacteria directly activate pain sensors, triggering immediate pain and inflammatory responses. This finding by a multinational team of researchers led by Professor Karel Talavera (KU Leuven, Belgium) and Professor Félix Viana (Institute of Neuroscience, Spain) sheds new light on pain associated with bacterial infections and reveals a new target for drugs designed to treat them.

11 Feb 2014

Targacept completes patient recruitment in TC-5214 Phase 2b study for treatment of overactive bladder

Targacept, Inc., a clinical-stage biopharmaceutical company developing novel NNR Therapeutics, today announced that it has completed recruitment of patients in its Phase 2b clinical study of TC-5214 as a treatment for overactive bladder (OAB).

10 Feb 2014

e-Therapeutics initiates Phase I clinical trial with oral formulation of ETS2101 anti-cancer compound

e-Therapeutics plc (AIM:ETX) announced today that it has dosed the first healthy volunteer in a newly initiated Phase I clinical trial with an oral formulation of its anti-cancer compound, ETS2101.

10 Feb 2014

Scientists find a clue as to why muscles weaken with age

Scientists from the School of Medicine at The University of Texas Health Science Center at San Antonio have found a clue as to why muscles weaken with age. In a study published Feb. 5 in The Journal of Neuroscience, they report the first evidence that "set points" in the nervous system are not inalterably determined during development but instead can be reset with age. They observed a change in set point that resulted in significantly diminished motor function in aging fruit flies.

9 Feb 2014

BGSU's Olivucci leverages OSC systems to study retina's melanopsin pigment

Researchers have found that the melanopsin pigment in the eye is potentially more sensitive to light than its more famous counterpart, rhodopsin, the pigment that allows for night vision.

9 Feb 2014

Moderate aerobic exercise helps preserve nerve cells in retina after damage

Moderate aerobic exercise helps to preserve the structure and function of nerve cells in the retina after damage, according to an animal study appearing February 12 in The Journal of Neuroscience. The findings suggest exercise may be able to slow the progression of retinal degenerative diseases.

9 Feb 2014

Researchers identify protein that regulates how genetic information transcribed from DNA to mRNA

Molecular biologists from Indiana University are part of a team that has identified a protein that regulates the information present in a large number of messenger ribonucleic acid molecules that are important for carrying genetic information from DNA to protein synthesis.

7 Feb 2014

Study provides evidence for importance of omega-3 fatty acids in healthy brain development

Monkeys that ate a diet rich in omega-3 fatty acids had brains with highly connected and well organized neural networks - in some ways akin to the neural networks in healthy humans - while monkeys that ate a diet deficient in the fatty acids had much more limited brain networking, according to an Oregon Health & Science University study.

5 Feb 2014

Furiex announces top-line results of Phase III clinical trials of eluxadoline in treatment of IBS-d

Furiex Pharmaceuticals, Inc. (NASDAQ: FURX) today announced top-line results indicating the company's two pivotal Phase III clinical trials evaluating the efficacy and safety of eluxadoline in the treatment of diarrhea-predominant irritable bowel syndrome (IBS-d) met both the U.S. Food and Drug Administration (FDA) and the European Medicines Agency (EMA) formally agreed-upon primary endpoints of composite response based on simultaneous improvements in stool consistency and abdominal pain.

4 Feb 2014

Scientists use SWI to study changes in brains of college-level ice hockey players with concussion

Using susceptibility-weighted imaging (SWI), researchers have identified microstructural changes in the brains of male and female college-level ice hockey players that could be due to concussive or subconcussive trauma.

4 Feb 2014

Study focuses on development and spread of Alzheimer's disease throughout the brain

The development of Alzheimer's disease and the way it spreads throughout the brain will be the focus of a pioneering study conducted at Aston University (UK).

4 Feb 2014

Selcia, University of Edinburgh collaborate to develop novel treatments for sleeping sickness

An initiative is under way to develop new drugs for a devastating tropical disease that threatens almost 70 million people in Africa.

4 Feb 2014

ACE protein overexpression elevates immune responses and prevents Alzheimer's-like cognitive decline

Many people with high blood pressure are familiar with ACE inhibitors, drugs that widen blood vessels by limiting activity of ACE - angiotensin-converting enzyme - a naturally occurring protein found in tissues throughout the body.

4 Feb 2014

Study shows how pesticides may contribute to development of Parkinson's disease

New research shows how pesticides may increase the risk of Parkinson's disease and that people with certain gene variants may be more susceptible to the disease. The research is published in the February 4, 2014, print issue of Neurology®, the medical journal of the American Academy of Neurology.

4 Feb 2014

New American Cancer Society report calls diagnosis of childhood cancer

A new report from the American Cancer Society outlines progress made and -more importantly-challenges that remain in fighting childhood cancer. The report estimates the number of new cancer cases and deaths for children and adolescents in the United States, summarizes the most recent and comprehensive data on cancer incidence, mortality, and survival, and outlines what is known and where answers are still needed for childhood cancers.

31 Jan 2014

Nervous System News and Research

Latest Nervous System News and Research

Jazz Pharmaceuticals' Versacloz now commercially available in the U.S. for schizophrenia

New approach for reducing levels of toxic protein fragments associated with Huntington's disease

Omeros announces additional positive data from OMS824 Phase 1 program

Transcendental meditation technique shows significant reduction in PTSD in just 10 days

Long-distance signaling molecules tell brain to produce anti-viral interferon

Researchers shed new light on pain associated with bacterial infections

Targacept completes patient recruitment in TC-5214 Phase 2b study for treatment of overactive bladder

e-Therapeutics initiates Phase I clinical trial with oral formulation of ETS2101 anti-cancer compound

Scientists find a clue as to why muscles weaken with age

BGSU's Olivucci leverages OSC systems to study retina's melanopsin pigment

Moderate aerobic exercise helps preserve nerve cells in retina after damage

Researchers identify protein that regulates how genetic information transcribed from DNA to mRNA

Study provides evidence for importance of omega-3 fatty acids in healthy brain development

Furiex announces top-line results of Phase III clinical trials of eluxadoline in treatment of IBS-d

Scientists use SWI to study changes in brains of college-level ice hockey players with concussion

Study focuses on development and spread of Alzheimer's disease throughout the brain

Selcia, University of Edinburgh collaborate to develop novel treatments for sleeping sickness

ACE protein overexpression elevates immune responses and prevents Alzheimer's-like cognitive decline

Study shows how pesticides may contribute to development of Parkinson's disease

New American Cancer Society report calls diagnosis of childhood cancer

Transforming Cardiovascular Care: Insights from Mina Makar at AstraZeneca

Clue's CEO Rhiannon White on the Future of Femtech and PCOS

Freezing Point Osmometry in Life Science Applications

Nervous System News and Research

Latest Nervous System News and Research

Transforming Cardiovascular Care: Insights from Mina Makar at AstraZeneca

Clue's CEO Rhiannon White on the Future of Femtech and PCOS

Freezing Point Osmometry in Life Science Applications

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