Nervous System News and Research

Latest Nervous System News and Research

Researchers assess how isolation and alcohol exposure alter ketamine intake

Ketamine can effectively treat depression, but whether depressed patients with alcohol use disorder can safely use ketamine repeatedly remains unclear clinically.

24 Feb 2025

"Normal" vitamin B12 levels may not prevent brain decline

Researchers identify associations between B12 levels currently accepted as normal and markers of neurological injury or impairment.

24 Feb 2025

Considerations for taking ASO discovery programs into animal models

ALS therapy can be drastically advanced with the help of ASOs.

From Charles River Labs - Neuroscience Discovery Services 24 Feb 2025

Exploring the link between cholestasis and depression

Announcing a new publication for Acta Materia Medica journal. The prevalence of depressive-like behavior is significantly higher in patients with cholestatic liver disease, leading to a notable reduction in the quality of life.

23 Feb 2025

Co-prescribing stimulants and opioids may fuel the twin epidemic of overdose

The combination of prescribed central nervous system stimulants, such as drugs that relieve ADHD symptoms, with prescribed opioid medications is associated with a pattern of escalating opioid intake, a new study has found.

22 Feb 2025

AI-driven discovery unveils TNIK inhibition as anti-aging strategy

A groundbreaking study led by researchers at Insilico Medicine has revealed the potential of TNIK inhibition as an innovative anti-aging strategy.

22 Feb 2025

Harbour BioMed partners with Insilico to accelerate AI-powered antibody discovery

Harbour BioMed (HKEX: 02142, the "Company"), a global biopharmaceutical company committed to the discovery, development and commercialization of novel antibody therapeutics focusing on immunology and oncology, and Insilico Medicine ("Insilico"), a clinical stage generative artificial intelligence (AI)-driven biotechnology company, today announced a strategic collaboration to accelerate the discovery and development of innovative therapeutic antibodies, leveraging their respective technological strengths in antibody discovery and artificial intelligence.

21 Feb 2025

Neurofilament light as a translational biomarker from preclinical drug discovery to clinical application

Neurofilament light (NFL) is a powerful and sensitive biomarker for tracking neuronal health and disease progression.

From Charles River Labs - Neuroscience Discovery Services 21 Feb 2025

Exploring how 25-hydroxycholesterol triggers ferroptosis in glial cells

Oxysterols are a class of molecules derived from cholesterol via oxidation or as byproducts of cholesterol synthesis.

20 Feb 2025

Can chili peppers improve ADHD symptoms? Scientists explore their gut-brain connection

Chili peppers may influence ADHD symptoms by modulating the gut microbiome, with capsaicin, vitamin C, and omega-3 fatty acids showing potential effects on neurotransmitters and inflammation. However, clinical trials are needed to confirm their efficacy.

20 Feb 2025

Unfolded protein response disruptions contribute to colorectal cancer and gut-related disorders

The intestinal epithelium is a highly dynamic barrier that regulates digestion, absorption, immune responses, and communication between the gut microbiota and the nervous system.

20 Feb 2025

Smoking linked to unexplained strokes in younger adults

Smoking, particularly heavy smoking, is linked to some unexplained strokes in younger adults, mainly in male individuals and in people ages 45 to 49, according to a study published in the February 19, 2025, online issue of Neurology Open Access, an official journal of the American Academy of Neurology.

20 Feb 2025

Infant exposure to herpes virus may cause memory problems later in life

Very early exposure to even a very small dose of herpes simplex virus (HSV) in infant mice can lead to cognitive decline later in life, according to findings from a new Dartmouth-led study, in collaboration with Harvard Medical School and published in the journal PLoS Pathogens.

19 Feb 2025

Study shows rapid transformation in multiple sclerosis treatment in Finland

A registry study led by the University of Oulu examined the early-stage treatment of relapsing-remitting multiple sclerosis (MS) in Finland between 2013 and 2022.

19 Feb 2025

Neuroestrogens likely contribute to appetite regulation

Although a woman's ovaries produce the most estrogen, various types of estrogen are also synthesized throughout different tissues in the body, including the brain's neurons.

19 Feb 2025

Study shows promise for new treatment approach for multiple sclerosis

A sponge-like implant in mice helped guide a treatment that slowed or stopped a degenerative condition similar to multiple sclerosis in humans. It also gave University of Michigan researchers a first look at how primary progressive multiple sclerosis, the fastest-progressing version of the disease, attacks the central nervous system early on.

19 Feb 2025

Researchers identify MLC1 as potential target in multiple sclerosis

Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system caused by the immune system. B cells, which are a type of white blood cell, play a role in the development of MS and are thus a target for therapies.

18 Feb 2025

New review maps the impact of reproductive hormones on neurological health

A comprehensive review published today in Brain Medicine by leading neuroendocrinologist Professor Hyman M. Schipper from McGill University's Department of Neurology and Neurosurgery maps out the extensive influence of reproductive hormones on neurological health and disease.

18 Feb 2025

How can machine learning accelerate neuroscience behavior studies?

Thanks to its capacity to detect patterns and stay consistent, machine learning is a great tool for CNS behaviour studies.

From Charles River Labs - Neuroscience Discovery Services 18 Feb 2025

Pancreatic cancer reprograms nerve cells to fuel growth

Pancreatic cancer is fueled by connections to the nervous system. This is reported by scientists from the German Cancer Research Center (DKFZ) and the Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM) in their current publication in Nature.

17 Feb 2025