Neurology News and Research

Latest Neurology News and Research

SynAgile announces positive results from Phase 2a trial of continuous intraoral LD/CD therapy

SynAgile Corporation, a privately held pharmaceutical company that develops and commercializes drug delivery systems using its proprietary OraFuse intraoral technology platform, today announced positive results from a proof-of-concept, Phase 2a, open-label clinical trial of continuous intraoral administration of levodopa-carbidopa (LD/CD).

8 Oct 2015

Clinical study data on Mallinckrodt's H.P. Acthar Gel to be presented at ACR 2015

Mallinckrodt plc, a leading specialty biopharmaceutical company, today announced that data from a pilot study for its H.P. Acthar Gel (repository corticotropin injection) will be presented at the American College of Rheumatology 2015 Annual Meeting to be held November 7-11 in San Francisco.

8 Oct 2015

Study: Sun exposure during teenage years may delay onset of multiple sclerosis

A study of people with multiple sclerosis (MS) found that those who spent time in the sun every day during the summer as teens developed the disease later than those reporting not spending time in the sun every day.

8 Oct 2015

Claritas Genomics announces launch of Claritas Clinical Exome, novel diagnostic test

Claritas Genomics, Inc., announced the launch of its Claritas Clinical Exome, at the Annual Meeting of the American Society of Human Genetics running 10/6 – 10/10 in Baltimore, MD. This novel diagnostic test is the first to exploit the strengths of multiple DNA sequencing platforms simultaneously to deliver confirmed results for a patient’s clinical whole exome within 4 weeks, compared to the industry standard of 12 weeks or more. Patients with rare disease typically seek a diagnosis for 8-12 years, receiving 3-5 separate tests at a high cost.

7 Oct 2015

Invitae announces dramatic expansion of genetic testing menu

Invitae Corporation (NYSE: NVTA), a genetic information company, has announced that it has more than doubled the size of its genetic testing platform to include more than 600 genes and will begin releasing the new content between now and the end of the year. Invitae is immediately expanding its menu with dozens of new test panels for hereditary cancer, cardiovascular, neuromuscular, pediatric and other rare disorders.

7 Oct 2015

Interim data from long-term extension Tecfidera® (dimethyl fumarate) study

Biogen (NASDAQ: BIIB) will, this week, present data at the 31st Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) in Barcelona, Spain, demonstrating the efficacy and safety of TECFIDERA® (dimethyl fumarate) across a broad range of people with relapsing-remitting multiple sclerosis (RRMS).

7 Oct 2015

Training ASD individuals by repetition actually harms learning ability

Individuals with autism spectrum disorder (ASD) sometimes acquire a new behavior or skill only in a specific context, but they have difficulty transferring that learned skill or information to a new context.

6 Oct 2015

Body weight change in older women may aid in diagnosis, management of Alzheimer's disease

Researchers led by Deborah Gustafson, PhD, MS, professor of neurology at SUNY Downstate Medical Center, have shown that women with a gene variant (APOEe4 allele) associated with Alzheimer's disease experience a steeper decline in body mass index (BMI) after age 70 than those women without the version of the gene, whether they go on to develop dementia or not.

6 Oct 2015

U of T study provides hope for treating ALS and FTD

It's the most common cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), but until now scientists weren't sure how a specific gene caused these devastating diseases. Now researchers from the University of Toronto are one step closer to solving this incredibly complex puzzle, offering hope for treatment.

6 Oct 2015

Researchers identify role of microglia during early stages of Alzheimer's disease

For the first time, researchers have determined how toxic tau fibrils spread by the help of brain immune cells called microglia during the early stages of Alzheimer's disease (AD). The discovery of this new pathway may lead to a therapeutic target for AD, one that has not been previously identified.

5 Oct 2015

Calcitonin-gene related peptide antibody inhibition shows migraine prevention promise

TEV-48125, a monoclonal anti-calcitonin-gene related peptide antibody, is well tolerated and effective in the prevention of high-frequency episodic migraine and chronic migraine, findings from two phase IIb studies show.

2 Oct 2015

Anteroinferior encephalocele a rare but important epilepsy cause

Clinicians should actively search for anteroinferior encephaloceles in patients with treatment-refractory epilepsy, say researchers.

2 Oct 2015

Quitting smoking may delay secondary progressive MS onset

Patients who are smokers when diagnosed with relapsing–remitting multiple sclerosis may be able to delay the time to onset of progressive disease by quitting smoking, a study suggests.

1 Oct 2015

Minor infections, inadequate vaccinations increase stroke risk in children

Children who have suffered recent infections or have not received most or all of their vaccinations are at a higher risk for stroke, according to research published in the Sept. 30 issue of Neurology, the medical journal of the American Academy of Neurology.

1 Oct 2015

Using well-worded warning texts could reduce DNAs, potentially save NHS £64 million

As many as 400,000 missed hospital appointments a year could be prevented simply by using well-worded warning texts, potentially saving the NHS £64 million.

30 Sep 2015

Glowing protein may replace fiber optic cable as light source in optogenetics research

Optogenetics has taken neuroscience by storm in recent years because the technique allows scientists to study the brain conveniently in animals, activating or inhibiting selected groups of neurons at the flip of a switch. Most often, scientists use a fiber optic cable to deliver light into the brain.

30 Sep 2015

Collaborative approach may speed discovery of new preventive treatments for Alzheimer's disease

The future success of Alzheimer's prevention research could depend on the ability of researchers from different clinical trials to build collaborative relationships that facilitate the sharing of information, resources and expertise that may speed the discovery of new preventive treatments, according to leading Alzheimer's researchers who published a Perspectives article, "CAP--advancing the evaluation of preclinical Alzheimer disease treatments," online today in Nature Reviews Neurology.

30 Sep 2015

Predicting better immunotherapy response, neurological outcomes in adults with autoimmune cerebellar ataxia

While autoimmune cerebellar ataxia (a loss of muscle control coordination) can lead to severe disability with some patients becoming wheelchair-bound, there are factors that may help predict better immunotherapy response, according to the Mayo Clinic study published by JAMA Neurology.

30 Sep 2015

Serologic status and autoimmune cerebellar ataxia type predict treatment response

Patients with autoimmune cerebellar ataxia have better treatment responses and outcomes if they have the nonparaneoplastic form of the condition and are seropositive for neural plasma membrane protein or glutamic acid decarboxylase 65 antibodies, suggests research.

29 Sep 2015

New technology benefits child suffering from severe form of epilepsy

Brittany Brown has watched her daughter, Amaree, 6, struggle with hundreds of seizures every day for the past six years. Yes, hundreds. Every day.

26 Sep 2015

Neurology News and Research

Latest Neurology News and Research

SynAgile announces positive results from Phase 2a trial of continuous intraoral LD/CD therapy

Clinical study data on Mallinckrodt's H.P. Acthar Gel to be presented at ACR 2015

Study: Sun exposure during teenage years may delay onset of multiple sclerosis

Claritas Genomics announces launch of Claritas Clinical Exome, novel diagnostic test

Invitae announces dramatic expansion of genetic testing menu

Interim data from long-term extension Tecfidera® (dimethyl fumarate) study

Training ASD individuals by repetition actually harms learning ability

Body weight change in older women may aid in diagnosis, management of Alzheimer's disease

U of T study provides hope for treating ALS and FTD

Researchers identify role of microglia during early stages of Alzheimer's disease

Calcitonin-gene related peptide antibody inhibition shows migraine prevention promise

Anteroinferior encephalocele a rare but important epilepsy cause

Quitting smoking may delay secondary progressive MS onset

Minor infections, inadequate vaccinations increase stroke risk in children

Using well-worded warning texts could reduce DNAs, potentially save NHS £64 million

Glowing protein may replace fiber optic cable as light source in optogenetics research

Collaborative approach may speed discovery of new preventive treatments for Alzheimer's disease

Predicting better immunotherapy response, neurological outcomes in adults with autoimmune cerebellar ataxia

Serologic status and autoimmune cerebellar ataxia type predict treatment response

New technology benefits child suffering from severe form of epilepsy

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Transforming Cardiovascular Care: Insights from Mina Makar at AstraZeneca

Clue's CEO Rhiannon White on the Future of Femtech and PCOS

Freezing Point Osmometry in Life Science Applications

Neurology News and Research

Latest Neurology News and Research

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Transforming Cardiovascular Care: Insights from Mina Makar at AstraZeneca

Clue's CEO Rhiannon White on the Future of Femtech and PCOS

Freezing Point Osmometry in Life Science Applications

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