Neurology News and Research

Latest Neurology News and Research

Manipulating retinal recipient microenvironment impacts photoreceptor cell transplantation

A research team in the United Kingdom has found that insulin-like growth factor (IGF1) impacts cell transplantation of photoreceptor precursors by manipulating the retinal recipient microenvironment, enabling better migration and integration of the cells into the adult mouse retina.

12 Jul 2012

Scientists assemble timeline of brain changes that lead to Alzheimer's

Scientists have assembled the most detailed chronology to date of the human brain's long, slow slide into full-blown Alzheimer's disease.

12 Jul 2012

Communication between brain and muscle cells is short-lived without LRP4 protein

Communication between the brain and muscle must be strong for us to eat, breathe or walk. Now scientists have found that a protein known to be on the surface of muscle cells must be present in both tissues to ensure the conversation is robust.

12 Jul 2012

New book outlines cutting-edge approach to systematically address AD

ADEC Inc. - Worried about your memory? Many patients with Alzheimer's disease (AD) and individuals concerned about developing memory loss feel they have limited options. While there is no 'magic pill' to cure or prevent AD, a new book outlines a cutting-edge approach to systematically address this disease.

12 Jul 2012

Oligodendroglia cells: An interview with Jeffrey Rothstein

There are three principle cells in the brain: neurons and two types of glial cells. One type is called an astrocyte. These were well known to inactivate neurotransmitters like glutamate, and provide metabolic support to neurons.

11 Jul 2012

Research into “insulating” brain cells could help to cure neurodegenerative diseases such as ALS

Johns Hopkins researchers say they have discovered that the central nervous system's oligodendroglia cells, long believed to simply insulate nerves as they "fire" signals, are unexpectedly also vital to the survival of neurons. Damage to these insulators appears to contribute to brain injury in neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease for the Yankee baseball great who died from the disease.

11 Jul 2012

Neonate blood-brain barrier more intact than adults following stroke

The ability for substances to pass through the blood-brain barrier is increased after adult stroke, but not after neonatal stroke, according to a new study the UCSF that will be published July 11 in the Journal of Neuroscience.

11 Jul 2012

BP variability link to stroke risk reinforced

Analysis of data from the Women’s Health Initiative supports the contention that variability in a person’s blood pressure affects their risk for stroke.

10 Jul 2012

Seizure risk should not influence AVM treatment decisions

Choosing to treat patients with arteriovenous malformations surgically rather than conservatively has no bearing on their risk for seizures, suggest findings from the Scottish Audit of Intracranial Vascular Malformations.

10 Jul 2012

BP variability link to stroke risk reinforced

Analysis of data from the Women’s Health Initiative supports the contention that variability in a person’s blood pressure affects their risk for stroke.

10 Jul 2012

Neuroprotective effects underpin fingolimod benefits in MS

Fingolimod therapy reduces inflammatory activity and tissue loss in the brains of patients with multiple sclerosis, shows further analysis of the FREEDOMS trial.

10 Jul 2012

Researchers investigate whether PTSD is a brain disorder

Researchers at The University of Texas Health Science Center at Houston (UTHealth) are investigating whether post traumatic stress disorder (PTSD) is a brain disorder that can affect multiple parts of the body and cause lifelong illnesses.

10 Jul 2012

Disabling Nf1 gene makes stem cells from the third ventricle proliferate rapidly

Scientists showed in mice that disabling a gene linked to a common pediatric tumor disorder, neurofibromatosis type 1 (NF1), made stem cells from one part of the brain proliferate rapidly. But the same genetic deficit had no effect on stem cells from another brain region.

10 Jul 2012

SUNY Downstate receives PCORI award to develop mobile phone apps for stroke patients

SUNY Downstate Medical Center has received an award to develop mobile phone applications for stroke patients and their caregivers. Steven R. Levine, MD, professor of neurology and emergency medicine and vice chair of neurology at SUNY Downstate, is scientific principal investigator on the $500,000 award, which is from the federally funded Patient-Centered Outcomes Research Institute.

10 Jul 2012

Inspiration receives FDA clinical hold order for IB1001 phase III studies on hemophilia B

Ipsen announced today that its partner Inspiration Biopharmaceuticals Inc. (Inspiration) was notified by the Food and Drug Administration (FDA) that both clinical trials evaluating the safety and efficacy of IB1001, an investigational intravenous recombinant factor IX (rFIX) therapy for the treatment and prevention of bleeding episodes in people with hemophilia B, were placed on clinical hold.

10 Jul 2012

Critical care needs high in childhood stroke

Children with stroke frequently require admission to the intensive care unit, show findings from a population-based study.

9 Jul 2012

Regnite to treat primary restless legs syndrome launched in Japan

Astellas Pharma Inc. and XenoPort, Inc. announced today that Regnite (gabapentin enacarbil) Extended-Release Tablets will be launched in Japan on July 10, 2012. Regnite is approved in Japan for the treatment of moderate-to-severe primary restless legs syndrome (RLS).

9 Jul 2012

Bayer commences enrollment in BAY94-9027 Phase II/III trial for hemophilia A

Bayer HealthCare today announced the company has started to enroll patients in an international Phase II/III trial to evaluate its investigational compound BAY94-9027 for the treatment of hemophilia A.

8 Jul 2012

Mouse model demonstrates role of AEG-1 in hepatocellular carcinoma

Researchers have created the first mouse model demonstrating the role of a cancer promoting gene, Astrocyte elevated gene-1 (AEG-1), in hepatocellular carcinoma, or liver cancer. The mouse model represents a critical step in understanding the molecular mechanisms of liver cancer progression and could lead to novel therapies for the disease.

8 Jul 2012

Scientists train visually impaired to perform fast and accurate movements using EyeMusic

Sensory substitution devices (SSDs) use sound or touch to help the visually impaired perceive the visual scene surrounding them. The ideal SSD would assist not only in sensing the environment but also in performing daily activities based on this input.

6 Jul 2012