Neurology News and Research

Latest Neurology News and Research

Bayer submits regorafenib NDA with FDA for treatment of mCRC

Bayer HealthCare announced today that it has submitted a New Drug Application (NDA) to the U.S. Food and Drug Administration (FDA) seeking approval for the oral multi-kinase inhibitor regorafenib for the treatment of patients with metastatic colorectal cancer.

24 May 2012

Alteplase can benefit stroke patients aged over 80 years according to new studies

The Lancet today publishes two papers Online First about the use of alteplase in stroke, timed to coincide with their presentation at the European Stroke Conference in Lisbon, Portugal.

23 May 2012

Botch protein appears to play an important regulatory role in forming neurons, other cell types

Johns Hopkins scientists have discovered a protein that appears to play an important regulatory role in deciding whether stem cells differentiate into the cells that make up the brain, as well as countless other tissues.

23 May 2012

Statins may reduce hospital stay for patients with stroke

A new study suggests that using cholesterol-lowering medications known as statins after having a stroke may increase the likelihood of returning home and lessen the chance of dying in the hospital.

22 May 2012

Bayer’s Nexavar Phase 3 trial on NSCLC does not meet primary endpoint

Bayer HealthCare Pharmaceuticals and Onyx Pharmaceuticals, Inc. today announced that a Phase 3 trial evaluating Nexavar (sorafenib) tablets in patients with advanced relapsed or refractory non-squamous non-small cell lung cancer (NSCLC) whose disease progressed after two or three previous treatments, did not meet its primary endpoint of improving overall survival.

22 May 2012

$Children with pelvic and thigh fractures rarely develop dangerous blood clots$

Children with pelvic and thigh fractures rarely develop dangerous blood clots

Children with pelvic and thigh fractures develop dangerous blood clots so rarely that anti-clotting therapy should be given only to those with underlying conditions that increase clotting risk, according to a study from Johns Hopkins Children's Center.

21 May 2012

Large neurological problems could be addressed through changing Botch activity

21 May 2012

Ipsen, Active Biotech complete half of planned recruitment in tasquinimod phase III study for CRPC

Active Biotech and Ipsen today announced that recruitment to the global, pivotal, randomized, double-blind, placebo-controlled phase III study of tasquinimod in patients with metastatic castrate-resistant prostate cancer (CRPC) has reached an inclusion of 600 patients, half of the planned accrual.

21 May 2012

Study uncovers mechanism by which Notch pathway could contribute to RA

A new study led by researchers at Hospital for Special Surgery identifies the mechanism by which a cell signaling pathway contributes to the development of rheumatoid arthritis (RA). In addition, the study provides evidence that drugs under development for diseases such as cancer could potentially be used to treat RA.

21 May 2012

Certain types of fat associated with worse memory and overall cognitive function

It has been known for years that eating too many foods containing "bad" fats, such as saturated fats or trans fats, isn't healthy for your heart. However, according to new research from Brigham and Women's Hospital (BWH), one "bad" fat-saturated fat-was found to be associated with worse overall cognitive function and memory in women over time. By contrast, a "good" fat-mono-unsaturated fat was associated with better overall cognitive function and memory.

19 May 2012

Study examines cognitive effects of head impacts among student athletes

Dartmouth faculty and students played prominent roles in a recent study on the cognitive effects of head impacts among student athletes. Tested at the beginning and end of one season, 22 percent of those students who participated in contact sports scored significantly lower in memory and learning skills than expected, as opposed to only 4 percent of non-contact sport athletes.

19 May 2012

Migraine is a neurological, not vascular, disorder

The latest genetic and biological research shows that migraine is a neurological, not vascular, disorder and both acute and preventive treatments being developed target peripheral and central nervous systems, according to a prominent migraine expert addressing the American Pain Society (APS)today.

18 May 2012

Ipsen, Active Biotech to present data from tasquinimod phase II trial on CRPC at ASCO 2012

Active Biotech and Ipsen will present tasquinimod (TASQ), their prostate cancer drug candidate, at the scientific conference "2012 ASCO Annual Meeting" to be held in Chicago (USA) on 1-5 June 2012.

18 May 2012

Study demonstrates impact of epilepsy on child and parent sleep patterns

Researchers from Massachusetts General Hospital for Children in Boston have determined that pediatric epilepsy significantly impacts sleep patterns for the child and parents. According to the study available in Epilepsia, a journal published by Wiley-Blackwell on behalf of the International League Against Epilepsy (ILAE), sharing a room or co-sleeping with their child with epilepsy decreases the sleep quality and prevents restful sleep for parents.

18 May 2012

APS announces recipients of prestigious achievement awards

The American Pain Society (APS), www.ampainsoc.org, today announced the recipients of its prestigious achievement awards during the organization's annual scientific meeting. APS rewards excellence in pain management with awards for career achievement, pain scholarship, education and public service, advocacy on behalf of children, outstanding service to APS, early career achievements and journalism.

18 May 2012

Damage to brain white matter connections may be the cause of Phineas Gage's behavioral changes

Poor Phineas Gage. In 1848, the supervisor for the Rutland and Burlington Railroad in Vermont was using a 13-pound, 3-foot-7-inch rod to pack blasting powder into a rock when he triggered an explosion that drove the rod through his left cheek and out of the top of his head. As reported at the time, the rod was later found, "smeared with blood and brains."

17 May 2012

Head impacts may worsen contact sport athletes’ ability to acquire new information

A new study suggests that head impacts experienced during contact sports such as football and hockey may worsen some college athletes' ability to acquire new information. The research is published in the May 16, 2012, online issue of Neurology, the medical journal of the American Academy of Neurology.

17 May 2012

Results from Boehringer Ingelheim’s LUX-Lung 3 Phase III trial on stage IIIB or IV NSCLC

Boehringer Ingelheim will present results from LUX-Lung 3, the company's pivotal Phase III clinical trial investigating afatinib in patients with stage IIIB or IV non-small cell lung cancer (NSCLC) harboring an epidermal growth factor receptor (EGFR) mutation (EGFR M+), at the 48th Annual Meeting of the American Society of Clinical Oncology (ASCO) in Chicago, June 1-5, 2012.

17 May 2012

Dangerous, complex migraines linked to high risk for stroke

Nicole Soriano had headaches before but nothing like the one that struck in the middle of one summer night. A coincidence led nine days later to Cedars-Sinai Medical Center, where a rare type of migraine was diagnosed and treated - but any moment during that time could have been disastrous.

16 May 2012

Delayed loss of nerve cells in the brain linked to symptoms of depression following stroke

Several weeks after mild brain ischemia, mice display a depressive-like syndrome characterized by increased anxiety, inactivity and "cheerlessness". These symptoms of depression following a stroke are associated with the delayed loss of nerve cells in the brain's reward regions. This is the major finding of a study published in the current issue of Biological Psychiatry.

16 May 2012

Neurology News and Research

Latest Neurology News and Research

Bayer submits regorafenib NDA with FDA for treatment of mCRC

Alteplase can benefit stroke patients aged over 80 years according to new studies

Botch protein appears to play an important regulatory role in forming neurons, other cell types

Statins may reduce hospital stay for patients with stroke

Bayer’s Nexavar Phase 3 trial on NSCLC does not meet primary endpoint

Children with pelvic and thigh fractures rarely develop dangerous blood clots

Large neurological problems could be addressed through changing Botch activity

Ipsen, Active Biotech complete half of planned recruitment in tasquinimod phase III study for CRPC

Study uncovers mechanism by which Notch pathway could contribute to RA

Certain types of fat associated with worse memory and overall cognitive function

Study examines cognitive effects of head impacts among student athletes

Migraine is a neurological, not vascular, disorder

Ipsen, Active Biotech to present data from tasquinimod phase II trial on CRPC at ASCO 2012

Study demonstrates impact of epilepsy on child and parent sleep patterns

APS announces recipients of prestigious achievement awards

Damage to brain white matter connections may be the cause of Phineas Gage's behavioral changes

Head impacts may worsen contact sport athletes’ ability to acquire new information

Results from Boehringer Ingelheim’s LUX-Lung 3 Phase III trial on stage IIIB or IV NSCLC

Dangerous, complex migraines linked to high risk for stroke

Delayed loss of nerve cells in the brain linked to symptoms of depression following stroke

Aneuro: Advancing Neuroscience Research eBook

Transforming Cardiovascular Care: Insights from Mina Makar at AstraZeneca

Clue's CEO Rhiannon White on the Future of Femtech and PCOS

Freezing Point Osmometry in Life Science Applications

Neurology News and Research

Latest Neurology News and Research

Aneuro: Advancing Neuroscience Research eBook

Transforming Cardiovascular Care: Insights from Mina Makar at AstraZeneca

Clue's CEO Rhiannon White on the Future of Femtech and PCOS

Freezing Point Osmometry in Life Science Applications

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