Neurology News and Research

Latest Neurology News and Research

Frailty increases a person's risk of dementia, study finds

An international study led by a University of Queensland researcher has found frailty increases a person's risk of dementia, but early intervention may be the key to prevention.

11 Nov 2024

GLP-1 and SGLT2 inhibitors show promise in preventing recurrent stroke and heart attack

GLP-1 receptor agonists and SGLT2 inhibitors, two classes of medications most commonly prescribed to treat Type 2 diabetes or weight loss, may reduce the risk of heart attack, second strokes and death in adults who had an initial stroke, according to a preliminary study to be presented at the American Heart Association's Scientific Sessions 2024.

11 Nov 2024

Genetic diagnosis solves medical mystery for 30 undiagnosed patients

An international team of researchers has provided a genetic diagnosis for 30 individuals whose condition was undiagnosed for years despite extensive clinical or genetic testing.

8 Nov 2024

Exploring the current use and future of alternatives to traditional informed consent in acute stroke trials

The University of Cincinnati's Yasmin Aziz, MD, and Joseph Broderick, MD, coauthored an editorial published Nov. 7 in the journal Neurology analyzing the current use and potential future of alternatives to traditional informed consent in acute stroke trials.

8 Nov 2024

Study reveals high prevalence of unrecognized cognitive impairment in vulnerable older adults

One of the first studies to investigate the prevalence of unrecognized cognitive impairment among patients seen at Federally Qualified Health Centers, has found that it is ubiquitous, especially among minoritized older adults.

8 Nov 2024

C-Path announces important leadership appointments in neurology and Alzheimer's research

Critical Path Institute (C-Path) today announced key leadership appointments: Diane Stephenson, Ph.D., has been promoted to Vice President of Neurology, and Nadine Tatton, Ph.D., has been welcomed as the new Executive Director of C-Path's Critical Path for Alzheimer's Disease (CPAD) Consortium.

7 Nov 2024

Healthy lifestyle choices can offset genetic risk for brain diseases

Christopher D. Anderson, MD, MSc, chief of the Division of Stroke and Cerebrovascular Diseases at Brigham and Women's Hospital and associate neurologist in the Department of Neurology and Center for Genomic Medicine at Massachusetts General Hospital, is the corresponding author and Jonathan Rosand, MD, MSc, co-founder of the McCance Center for Brain Health and neurologist in the Department of Neurology and Center for Genomic Medicine at Massachusetts General Hospital, is an author of a paper published on November 6, 2024, in Neurology, the medical journal of the American Academy of Neurology, "Health-related behaviors and risk of common age-related brain diseases across severities of genetic risk."

6 Nov 2024

Daytime sleepiness and low enthusiasm may be linked to motoric cognitive risk syndrome

Older people who are sleepy during the day or lack enthusiasm for activities due to sleep issues may be more likely to develop a syndrome that can lead to dementia, according to a study published in the November 6, 2024, online issue of Neurology®, the medical journal of the American Academy of Neurology.

6 Nov 2024

Brain cells form multiple coordinate systems to guide behavioral actions

Neuroscientists have discovered brain cells that form multiple coordinate systems to tell us "where we are" in a sequence of behaviors.

6 Nov 2024

AI model predicts Alzheimer’s progression with new insights into racial and sex-based disparities

Researchers developed a deep learning model that predicts Alzheimer’s progression with high accuracy, highlighting differences in disease progression across race and sex.

5 Nov 2024

New technology for visualizing AMPA receptors offers insights into psychiatric disorders

Even though psychiatric disorders such as schizophrenia, bipolar disorder, and autism spectrum disorder (ASD) are quite common, their diagnosis and treatment are challenging.

5 Nov 2024

Revised diagnostic criteria seek to avoid over-diagnosis of Alzheimer’s disease

Diagnosis of Alzheimer's Disease (AD) is currently largely based on the presence of biomarkers. This may lead to a problematic over-diagnosis if this is incorrectly interpreted.

5 Nov 2024

New Alzheimer's guidelines focus on risk, not diagnosis, in healthy adults

Researchers from the International Working Group recommend categorizing biomarker-positive, cognitively normal individuals as "at risk" for Alzheimer's to avoid unnecessary diagnoses and emphasize preventive care.

4 Nov 2024

New model sheds light on APOE4's role in Alzheimer's pathology

In healthy brains, immune cells called microglia patrol for damage, clearing away debris and harmful proteins. But in the presence of the APOE4 protein-;the most important genetic risk factor for Alzheimer's disease-;the same cells cause harmful inflammation and clumps of misfolded proteins, according to a new study by scientists at Gladstone Institutes.

4 Nov 2024

Researchers achieve accurate EV analysis to detect brain disease

Brain disorders like Parkinson's (PD) or Alzheimer's Disease (AD) start to develop in patients much earlier than when their first clinical symptoms appear. Treating patients at these early stages could slow or even stop their disease, but there is currently no way to diagnose brain disorders at those pre-symptomatic stages.

3 Nov 2024

International experts propose revised Alzheimer's disease definitions

Today, Prof. Howard Feldman presented revised diagnostic criteria for Alzheimer's disease at the Clinical Trials on Alzheimer's Disease (CTAD) Conference in Madrid on behalf of the International Working Group (IWG).

1 Nov 2024

Study links brain proteins to individual differences in functional connectivity

A long-standing goal of neuroscience is to understand how molecules and cellular structures on a microscale give rise to communication between brain regions at the macroscale.

1 Nov 2024

Study links obstructive sleep apnea to increased dementia risk in women

A common yet underdiagnosed sleep disorder contributes to the development of dementia among adults -; particularly women, a Michigan Medicine study suggests.

1 Nov 2024

NIH grant funds study to understand how chemical exposure impacts Alzheimer’s risk

To better understand how day-to-day exposures to chemicals earlier in life can contribute to conditions like Alzheimer's disease later on, researchers at the Perelman School of Medicine of the University of Pennsylvania, Northwestern University, University of California San Francisco, and Emory University received an $11 million National Institutes of Health grant

30 Oct 2024

Researchers identify genetic markers linked to neuropathic pain

European researchers have mapped the most comprehensive phenotyping of neuropathic pain and identified genetic markers associated with this serious condition.

30 Oct 2024