Obesity News and Research

Latest Obesity News and Research

Intravenous infusion of exenatide fails to reduce risks of complications in heart surgery patients

A large-scale clinical trial found that intravenous infusion of exenatide, a glucagon-like peptide-1 (GLP-1) analog medication, during heart surgeries involving bypass did not significantly reduce the risk of death, stroke or organ failure.

18 Nov 2024

Tirzepatide improves heart health and function in obese HFpEF patients

In the international SUMMIT trial, adults with heart failure preserved ejection fraction (HFpEF) and obesity taking tirzepatide for up to 3 years had a reduced combined risk of worsening heart failure events and cardiovascular death, and improved health status and physical function in comparison to participants taking placebo, according to late-breaking science presented today at the American Heart Association's Scientific Sessions 2024.

18 Nov 2024

AI algorithm accurately detects early-stage metabolic-associated steatotic liver disease

Liver disease, which is treatable when discovered early, often goes undetected until late stages, but a new study revealed that an algorithm fueled by artificial intelligence can accurately detect early-stage metabolic-associated steatotic liver disease (MASLD) by using electronic health records.

18 Nov 2024

Monash researchers develop model to tackle weight stigma in pregnancy and beyond

People with larger bodies commonly face a pervasive, resilient form of social stigma, often facing discrimination in the workplace as well as in educational and healthcare settings.

18 Nov 2024

Diabetes rates skyrocket globally with millions left untreated

The total number of adults living with either type 1 or type 2 diabetes in the world has surpassed 800 million - over four times the total number in 1990, according to findings from a global analysis published ahead of World Diabetes Day in The Lancet.

18 Nov 2024

Spermidine regulates RIPK1 to combat diabetes and vascular damage

Researchers reveal that spermidine-mediated acetylhypusination of RIPK1 suppresses necroptosis and insulin resistance, offering potential therapeutic strategies for type 2 diabetes.

18 Nov 2024

Gut microbiome found to play key role in chronic disease progression

The gut microbiome, an ecosystem of trillions of microorganisms in the human digestive tract, has been increasingly linked to chronic diseases.

15 Nov 2024

Obesity crisis in the U.S. expected to worsen by 2050

Over the past three decades, there has been a startling increase in the prevalence of obesity across the USA, at least doubling in adult men and women (aged 25 and older) and older female and male adolescents (aged 15-24 years) since 1990, with the number of people living with overweight and obesity reaching over 208 million in 2021-;a trend set to continue in the coming decades without significant reform, according to a major new analysis from the Global Burden of Disease Study Collaborator Network, published in The Lancet.

15 Nov 2024

Diabetes medication shows promise in reducing alcohol use

New research, led by experts at the University of Nottingham, has found that certain types of medication used to treat diabetes may be effective in reducing alcohol use.

15 Nov 2024

Global gap in diabetes prevalence and treatment has widened since 1990

Global diabetes rates have surged, particularly in low-resource areas, revealing critical gaps in treatment access and highlighting the need for improved care.

15 Nov 2024

Microbial density in our gut shapes how diseases are linked to gut health

The study in Cell highlights microbial load's role in gut microbiome variation, suggesting it as a confounder in disease research and a key health determinant.

15 Nov 2024

Inequalities in green space linked to preventable deaths in urban areas

Findings reveal that more green space in deprived neighborhoods is associated with lower mortality rates, advocating for strategic public health initiatives.

15 Nov 2024

Tirzepatide significantly reduces weight and diabetes risk in patients with obesity and prediabetes

Tirzepatide shows promise in reducing weight and preventing diabetes progression in people with obesity and prediabetes, with lasting benefits and manageable side effects.

14 Nov 2024

Global diabetes cases exceed 800 million highlighting urgent need for action

The number of adults living with diabetes worldwide has surpassed 800 million, more than quadrupling since 1990, according to new data released in The Lancet on World Diabetes Day.

14 Nov 2024

Update on diagnosis, risk classification and treatment of Kawasaki Disease

Advances in cardiac imaging techniques and risk categorization have led to improvements in diagnosis, initial treatment and long-term management of patients with Kawasaki Disease, according to a new scientific statement published today in the American Heart Association's flagship, peer-reviewed journal Circulation.

14 Nov 2024

Vitamin D may lower blood pressure in older people with obesity

Vitamin D3 supplementation with calcium reduces blood pressure in elderly, overweight individuals, particularly those with higher BMI and existing hypertension.

14 Nov 2024

Primary care clinicians key to achieving optimal cardiovascular health

Primary care clinicians and practices are uniquely positioned to help people achieve optimal cardiovascular health through screening, diagnosing and treating the health behaviors and factors outlined in the American Heart Association's Life's Essential 8 health metrics to reduce the risk for heart disease and stroke, according to a new scientific statement published today in the Association's peer-reviewed journal Circulation: Cardiovascular Quality and Outcomes.

13 Nov 2024

UAB researchers reverse liver disease in mice with gene therapy

UAB researchers have reversed metabolic dysfunction-associated steatohepatitis (MASH) in mouse models. MASH is a severe liver disease associated with obesity and type 2 diabetes that affects more than 40 million people.

13 Nov 2024

GLP-1 agonists linked to fewer hospitalizations in alcohol use disorder patients

A new joint study by the University of Eastern Finland and Karolinska Institutet in Sweden found that the GLP-1 agonists semaglutide and liraglutide, which are used for treating diabetes and obesity, were associated with fewer hospitalizations among individuals with alcohol use disorder, AUD.

13 Nov 2024

Scientists discover new breakthrough in weight loss and diabetes treatment

Scientists at the University of Copenhagen have discovered a new weight loss drug target that reduces appetite, increases energy expenditure, and improves insulin sensitivity without causing nausea or loss of muscle mass.

13 Nov 2024