Parkinson's Disease News and Research

Latest Parkinson's Disease News and Research

Support for enteric nervous system pathology in prodromal PD

Researchers have found positive immunostaining of α-synuclein in the enteric nervous system of patients with idiopathic rapid eye movement sleep behaviour disorder, suggesting it may have a possible role as a biomarker for prodromal Parkinson’s disease.

22 Oct 2015

Advances in Whole Mount Brain Imaging

An interview with Patrick Myles, discussing the digitization of whole mount slides and its impact on the field of neurobiological research.

From Huron Digital Pathology 20 Oct 2015

Breakthrough advancements on new molecular mechanism may lead to Parkinson's treatments

More than one million people in the United States are afflicted with Parkinson's disease, a progressive disorder of the brain that affects movement and coordination. The cause is typically unknown, and presently there is no cure for the disease.

19 Oct 2015

New research shows nicotine increases codeine-induced analgesia

According to new research in rat models, nicotine use over time increases the speed that codeine is converted into morphine within the brain, by increasing the amount of a specific enzyme. It appears smokers' brains are being primed for a bigger buzz from this common pain killer - which could put them at a higher risk for addiction, and possibly even overdose.

19 Oct 2015

Researchers find that stem cell treatment may reduce cognitive impairment related to dementia with Lewy bodies

Neural stem cells transplanted into damaged brain sites in mice dramatically improved both motor and cognitive impairments associated with dementia with Lewy bodies, according to University of California, Irvine neurobiologists with the Sue & Bill Gross Stem Cell Research Center and the Institute for Memory Impairments and Neurological Disorders.

19 Oct 2015

Doctors use MR-guided focused ultrasound to treat essential tremor

The Ohio State University Wexner Medical Center is one of six locations nationally - and the only one in the Midwest - studying the safety and effectiveness of a promising new technology using MR-guided focused ultrasound to treat patients suffering from essential tremor as part of a multi-center FDA trial.

18 Oct 2015

OHSU designs new iPhone app to advance melanoma research

Oregon Health & Science University today released an iPhone app designed to advance melanoma research by giving users the ability to accurately measure and monitor moles, and contribute photos of how their potential trouble spots evolve over time.

16 Oct 2015

New COMPASS platform points directly to protein's likely structure

Searching for the precise, complexly folded three-dimensional structure of a protein can be like hacking through a jungle without a map: a long, intensive process with uncertain direction.

16 Oct 2015

Researchers uncover how small heat shock protein interacts with other proteins

In Alzheimer's disease proteins clump together to long fibrils causing the death of nerve cells. Small heat shock proteins can counteract this effect. Scientists, therefore, hope to deploy them as agents in the treatment of neurodegenerative diseases. Using the example of a small heat shock protein, researchers at the Technical University of Munich and the Helmholtz Zentrum Muenchen have now uncovered how the protein interacts with other proteins.

15 Oct 2015

Developing tailored interventions for cognitive and behavioral symptoms key to improving outcomes after TBI

Kessler researchers assessed moderate to severe traumatic brain injury (TBI) for frontal behavioral syndromes and cognitive function. Their finding suggest that adding the Frontal Systems Behavior Scale to neuropsychological assessment may yield useful information about the behavioral sequelae of TBI.

15 Oct 2015

UTHealth biochemists expose structures of IP3R calcium channels

Calcium is a crucial element in the body that controls thought, movement and other bodily functions. These events are directed by specialized proteins called ion channels that allow the flow of calcium ions in and out of cells and among cell compartments. For years, scientists have been unsure how calcium ion channels function.

15 Oct 2015

Having a high stress job may increase risk of stroke

Having a high stress job may be linked to a higher risk of stroke, according to an analysis of several studies. The meta-analysis is published in the October 14, 2015, online issue of Neurology, the medical journal of the American Academy of Neurology.

15 Oct 2015

SonaCare Medical's Sonablate 450 focused ultrasound system receives FDA approval for ablation of prostate tissue

The US Food and Drug Administration has approved SonaCare Medical's Sonablate 450 focused ultrasound system for the ablation of prostate tissue. Focused ultrasound enables treatment of organ-confined prostate disease while preserving surrounding healthy tissue, without radiation or surgery.

14 Oct 2015

Cognitive decline common and rapid in Parkinson’s patients

Researchers report that nearly half of patients with Parkinson’s disease (PD) develop cognitive impairment within about a decade, and progress rapidly to dementia.

9 Oct 2015

Gene therapy prevents neuronal death, disease effects in experimental model of PD

An estimated seven to ten million people worldwide are living with Parkinson's disease (PD), which is an incurable and progressive disease of the nervous system affecting movement and cognitive function. More than half of PD patients develop progressive disease showing signs of dementia similar to Alzheimer's disease.

9 Oct 2015

Minor hallucinations may predate Parkinson motor symptoms

About four in 10 patients with untreated Parkinson’s disease experience minor hallucinations, research shows.

8 Oct 2015

SynAgile announces positive results from Phase 2a trial of continuous intraoral LD/CD therapy

SynAgile Corporation, a privately held pharmaceutical company that develops and commercializes drug delivery systems using its proprietary OraFuse intraoral technology platform, today announced positive results from a proof-of-concept, Phase 2a, open-label clinical trial of continuous intraoral administration of levodopa-carbidopa (LD/CD).

8 Oct 2015

Lund researchers one step closer to developing implantable electrodes for capturing brain function

For nearly nine years, researchers at Lund University have been working on developing implantable electrodes that can capture signals from single neurons in the brain over a long period of time - without causing brain tissue damage. They are now one big step closer to reaching this goal, and the results are published in the scientific journal Frontiers in Neuroscience.

8 Oct 2015

Study: Sun exposure during teenage years may delay onset of multiple sclerosis

A study of people with multiple sclerosis (MS) found that those who spent time in the sun every day during the summer as teens developed the disease later than those reporting not spending time in the sun every day.

8 Oct 2015

Dopamine transmission mediated by D1 receptors essential for controlling movements in Parkinson's disease

Dopamine deficiency in the basal ganglia (a set of subcortical structures) causes severe motor dysfunctions, such as slowness of movements (bradykinesia), as observed in Parkinson's disease. Dopamine binds D1 and D2 receptors that are expressed in the nerve cells of the striatum (a structure of the basal ganglia), and exerts different effects on the nerve cells. However, how dopamine controls through these receptors the information flow in the basal ganglia and voluntary movements is still not clear.

6 Oct 2015

Parkinson's Disease News and Research

Latest Parkinson's Disease News and Research

Support for enteric nervous system pathology in prodromal PD

Advances in Whole Mount Brain Imaging

Breakthrough advancements on new molecular mechanism may lead to Parkinson's treatments

New research shows nicotine increases codeine-induced analgesia

Researchers find that stem cell treatment may reduce cognitive impairment related to dementia with Lewy bodies

Doctors use MR-guided focused ultrasound to treat essential tremor

OHSU designs new iPhone app to advance melanoma research

New COMPASS platform points directly to protein's likely structure

Researchers uncover how small heat shock protein interacts with other proteins

Developing tailored interventions for cognitive and behavioral symptoms key to improving outcomes after TBI

UTHealth biochemists expose structures of IP3R calcium channels

Having a high stress job may increase risk of stroke

SonaCare Medical's Sonablate 450 focused ultrasound system receives FDA approval for ablation of prostate tissue

Cognitive decline common and rapid in Parkinson’s patients

Gene therapy prevents neuronal death, disease effects in experimental model of PD

Minor hallucinations may predate Parkinson motor symptoms

SynAgile announces positive results from Phase 2a trial of continuous intraoral LD/CD therapy

Lund researchers one step closer to developing implantable electrodes for capturing brain function

Study: Sun exposure during teenage years may delay onset of multiple sclerosis

Dopamine transmission mediated by D1 receptors essential for controlling movements in Parkinson's disease

eBook: Advancing neurodegenerative research with iPSC-derived microglia models eBook

Clue's CEO Rhiannon White on the Future of Femtech and PCOS

Freezing Point Osmometry in Life Science Applications

Precision in every drop: Inside Hamilton’s syringe technology

Parkinson's Disease News and Research

Latest Parkinson's Disease News and Research

eBook: Advancing neurodegenerative research with iPSC-derived microglia models eBook

Clue's CEO Rhiannon White on the Future of Femtech and PCOS

Freezing Point Osmometry in Life Science Applications

Precision in every drop: Inside Hamilton’s syringe technology

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