Parkinson's Disease News and Research

Latest Parkinson's Disease News and Research

MSC-mediated RNAi transfer holds promise for Huntington's disease

A team of researchers at the UC Davis Institute for Regenerative Cures has developed a technique for using stem cells to deliver therapy that specifically targets the genetic abnormality found in Huntington's disease, a hereditary brain disorder that causes progressive uncontrolled movements, dementia and death.

20 Jan 2012

A reliable way to replicate α-synuclein aggregation on cell membranes in Parkinson's disease patients

The accumulation of α-synuclein, a small, negatively charged protein, in neural cells, is one of the hallmarks of Parkinson's disease. It has been suggested that oligomeric α-synuclein causes membranes to become permeable, or to form channels on the outer cell membrane.

19 Jan 2012

Aspirin may benefit HIV-infected women at risk of cervical cancer

Research conducted by NewYork-Presbyterian Hospital/Weill Cornell Medical Center global health investigators and cancer specialists in New York, Qatar and Haiti suggests that aspirin should be evaluated for its ability to prevent development of cervical cancer in HIV-infected women.

19 Jan 2012

Slow-wriggling alpha-synuclein proteins cause Parkinson's disease

Imagine if doctors could spot Parkinson's disease at its inception and treat the protein that triggers it before the disease can sicken the patient.

18 Jan 2012

Defects in mitochondria lead to devastating neurodegenerative disease

A devastating neurodegenerative disease that first appears in toddlers just as they are beginning to walk has been traced to defects in mitochondria, the 'batteries' or energy-producing power plants of cells. This finding by a team of researchers, led by investigators from the Montreal Neurological Institute and Hospital - The Neuro- at McGill University, was published in this week's issue of the Proceedings of the National Academy of Sciences of the USA.

18 Jan 2012

Neuronal energy deficit may cause Parkinson's disease

Scientists at the University of York have made a significant step forward in isolating the cause of Parkinson's disease in younger adults.

17 Jan 2012

AAN neurologist receives prestigious award at Palatucci Advocacy Leadership Forum

The American Academy of Neurology(AAN) has named neurologist Constantine Moschonas, MD, of Scottsdale, Ariz., as the AAN Donald M. Palatucci Advocacy Leadership Forum Advocate of the Year. Moschonas received his award at the Palatucci Advocacy Leadership Forum on January 14, 2012, in Austin, Texas, for his outstanding work in raising awareness about brain diseases such as Alzheimer's disease, stroke, autism, Parkinson's disease and multiple sclerosis.

17 Jan 2012

Arm sling or cast use after injury may cause rapid brain shift

Using a sling or cast after injuring an arm may cause your brain to shift quickly to adjust, according to a study published in the January 17, 2012, print issue of Neurology-, the medical journal of the American Academy of Neurology.

17 Jan 2012

Lack of iron early in life can affect brain's physical structure

Iron is a popular topic in health news. Doctors prescribe it for medical reasons, and it's available over the counter as a dietary supplement. And while it's known that too little iron can result in cognitive problems, it's also known that too much promotes neurodegenerative diseases. Now, researchers at UCLA have found that in addition to causing cognitive problems, a lack of iron early in life can affect the brain's physical structure as well.

12 Jan 2012

Amarantus receives U.S. patent titled, 'Dopaminergic Neuronal Survival-Promoting Factors and Uses Thereof'

Amarantus BioSciences, Inc., a biotechnology company developing MANF, a first-in-class disease-modifying therapeutic protein, today announced U.S. Patent Number 8,084,425 has been issued for MANF entitled, Dopaminergic Neuronal Survival-Promoting Factors and Uses Thereof.

12 Jan 2012

DBS safe and effective for patients with advanced Parkinson's

Researchers from the University of Florida and 14 additional medical centers reported results today in the online version of The Lancet Neurology journal indicating that deep brain stimulation - also known as DBS - is effective at improving motor symptoms and quality of life in patients with advanced Parkinson's disease.

12 Jan 2012

IUPUI launches Institute for Mathematical Modeling and Computational Science

The School of Science at Indiana University-Purdue University Indianapolis has launched the Institute for Mathematical Modeling and Computational Science, an interdisciplinary endeavor dedicated to solving perplexing problems in such diverse fields as medicine, the environment, and computer science. iM2CS's parallel mission is to train a new generation to identify and solve the scientific issues with which they will be faced.

11 Jan 2012

Study finds no support for primary pathogenic role of LBs in PD

The pathology of Parkinson's disease is characterized by a loss of dopamine-producing neurons in the pars compacta of the substantia nigra (SN), an area of the brain associated with motor control, along with the development of α-synuclein (αS) protein in the form of Lewy bodies (LB) in the neurons that survive. The spread of LB pathology is thought to progress along with the clinical course of Parkinson's disease, although recent studies suggest that they are not the toxic cause of cell death.

10 Jan 2012

ORMOSIL nanoparticles show promise as potential drug delivery vehicle

In the images of fruit flies, clusters of neurons are all lit up, forming a brightly glowing network of highways within the brain. It's exactly what University at Buffalo researcher Shermali Gunawardena was hoping to see: It meant that ORMOSIL, a novel class of nanoparticles, had successfully penetrated the insects' brains. And even after long-term exposure, the cells and the flies themselves remained unharmed.

10 Jan 2012

Nicotine patch may help improve mild memory loss in older adults

Using a nicotine patch may help improve mild memory loss in older adults, according to a study published in the January 10, 2012, print issue of Neurology, the medical journal of the American Academy of Neurology.

10 Jan 2012

AAN, Wolters Kluwer Health announce launch of Neurology Today for the iPad

The American Academy of Neurology (AAN) and Wolters Kluwer Health today announced the launch of Neurology Today for the iPad, a digital app of the most widely read newspaper for neurologists.

10 Jan 2012

USPTO issues patent to Lixte's lead compounds for treatment of neurological diseases

Lixte Biotechnology Holdings announces that the United States Patent and Trademark Office awarded a patent for the use of lead compounds from each of two different types of drugs, protein phosphatase inhibitors and histone deacetylase inhibitors, for the potential prevention and treatment of neurodegenerative diseases.

9 Jan 2012

Novel class of nanoparticles hold promise as a potential vehicle for drug delivery

In the images of fruit flies, clusters of neurons are all lit up, forming a brightly glowing network of highways within the brain. It’s exactly what University at Buffalo researcher Shermali Gunawardena was hoping to see: It meant that ORMOSIL, a novel class of nanoparticles, had successfully penetrated the insects’ brains. And even after long-term exposure, the cells and the flies themselves remained unharmed.

9 Jan 2012

Georgia Bio announces 2012 Deals of the Year for pharma, biopharma and medical device companies

Georgia Bio announced its 2012 Deals of the Year for pharmaceutical, biopharmaceutical and medical device companies in four categories - public and private financings, fast growing companies, acquisitions and SBIR grants - reflecting a broad range of activity.

From Medtronic 7 Jan 2012

Studies identify genes and small molecules against protein conformational diseases

Two related studies from Northwestern University offer new strategies for tackling the challenges of preventing and treating diseases of protein folding, such as Alzheimer's, Parkinson's and Huntington's diseases, amyotrophic lateral sclerosis (ALS), cancer, cystic fibrosis and type 2 diabetes.

7 Jan 2012