Pediatrics News and Research

Latest Pediatrics News and Research

New insight into why glioblastoma multiforme recurs in adults

A study by UT Southwestern Medical Center researchers published online today in Nature reveals new insight into why the most common, deadly kind of brain tumor in adults recurs and identifies a potential target for future therapies.

2 Aug 2012

Researchers discover genetic process that can restore function to a CF defective protein

Researchers at the University of Iowa Carver College of Medicine have discovered a genetic process that can restore function to a defective protein, which is the most common cause of cystic fibrosis (CF).

2 Aug 2012

Pediatric liver transplant recipients have increased risk of death when from obese donors

Children undergoing liver transplantation are at greater risk of graft loss and death from adult organ donors who are severely obese according to research published in the August issue of Liver Transplantation, a journal of the American Association for the Study of Liver Diseases. The study, funded in part by a grant from the National Institutes of Health (NIH), found that pediatric donor body mass index (BMI) did not increase mortality risk in this pediatric population.

1 Aug 2012

Teplizumab type I diabetes prevention study now enrolls younger children

A type I diabetes prevention study that is part of the TrialNet program at Vanderbilt is now enrolling children as young as 8 years old, following an FDA decision allowing the drug Teplizumab (anti-CD3) to be used in younger children.

1 Aug 2012

Tips on how to keep children safe during extreme hot weather

Several US states and cities have seen record breaking temperatures this summer. Doctors at Cincinnati Children's Hospital Medical Center want to give tips to parents and guardians on how they can keep their kids safe during the hot weather.

31 Jul 2012

Obesity and heart disease risk in children: an interview with Joana Kist-van Holthe

'What defines obesity in children' is a very important question, primarily because we need to use one definition in order to be able to compare the prevalence of obesity in different countries. It is also important to have a single definition in order to evaluate whether interventions are successful or not.

31 Jul 2012

GenomePooling™ method is sensitive and accurate

Population Genetics Technologies Ltd., creator of innovative methods for genetic analyses and biomarker discovery, has successfully completed a pilot study to prove that its GenomePooling™ method is sensitive and accurate enough to detect even small percentages of gene variants within cancer tissue.

31 Jul 2012

Kids with congenital heart defect should receive early evaluation for developmental disorders

Children born with a congenital heart defect should receive early evaluation, prompt treatment and ongoing follow-up for related developmental disorders affecting brain function, according to a new American Heart Association scientific statement published in Circulation.

31 Jul 2012

Psychological abuse can be as damaging to young child's health as a slap, punch or kick

Child abuse experts say psychological abuse can be as damaging to a young child's physical, mental and emotional health as a slap, punch or kick.

31 Jul 2012

ATP1A3 gene mutations responsible for alternating hemiplegia of childhood

Alternating hemiplegia of childhood (AHC) is a rare disorder that usually begins in infancy, with intermittent episodes of paralysis and stiffness, first affecting one side of the body, then the other. Symptoms mysteriously appear and disappear, again and again, and affected children often experience dozens of episodes per week. As they get older, children fall progressively behind their peers in both intellectual abilities and motor skills, and more than half develop epilepsy.

31 Jul 2012

Enoxaparin prevents PVT in advanced cirrhosis

Enoxaparin significantly reduces portal vein thrombosis and increases overall survival in patients with advanced cirrhosis, the results of an Italian study show.

30 Jul 2012

Sunovion launches ZETONNA Nasal Aerosol for allergic rhinitis

Sunovion Pharmaceuticals Inc. today announced the nationwide availability of ZETONNA (ciclesonide) Nasal Aerosol, 74 mcg once-daily, for the treatment of allergic rhinitis (AR), also known as hay fever or nasal allergies. ZETONNA is a corticosteroid indicated for the treatment of symptoms associated with seasonal allergic rhinitis (SAR) and perennial allergic rhinitis (PAR) in adults and adolescents 12 years of age and older.

30 Jul 2012

Researchers discover gene mutations in patients with alternating hemiplegia of childhood

Alternating hemiplegia of childhood (AHC) is a very rare disorder that causes paralysis that freezes one side of the body and then the other in devastating bouts that arise at unpredictable intervals. Seizures, learning disabilities and difficulty walking are common among patients with this diagnosis.

30 Jul 2012

Childhood physical and sexual abuse may increase risk of early or late onset menarche

Researchers from Boston University School of Medicine (BUSM) have found an association between childhood physical and sexual abuse and age at menarche.

28 Jul 2012

Fusion of FGFR and TACC gene leads to glioblastoma

Researchers at Columbia University Medical Center (CUMC) have discovered that some cases of glioblastoma, the most common and aggressive form of primary brain cancer, are caused by the fusion of two adjacent genes.

26 Jul 2012

Brown fat fuels fight against obesity

Experts may have found a new method for assessing adipose tissue function that could be used in the fight against obesity.

26 Jul 2012

Child who received first stem cell trachea transplant functioning well two years on

The first child stem cell-supported trachea transplant is functioning well two years on, according to an Article published Online First in The Lancet today. The follow-up of the procedure, carried out in 2010 at Great Ormond Street Hospital (GOSH), shows that the new organ has strengthened and does not appear to have induced any signs of rejection. The 13-year-old boy who received the transplant continues to breathe normally, has grown 11 cm in height and has returned to school. He does not require any anti-rejection therapy.

26 Jul 2012

Excess maternal iodine supplementation can lead to congenital hypothyroidism in infants

Congenital hypothyroidism is thyroid hormone deficiency at birth that, if left untreated, can lead to neurocognitive impairments in infants and children. Although the World Health Organization recommends 200-300 -g of iodine daily during pregnancy for normal fetal thyroid hormone production and neurocognitive development, the US Institute of Medicine considers 1,100 -g to be the safe upper limit for daily ingestion.

26 Jul 2012

Single event of brain trauma can lead to Alzheimer’s

A study, performed in mice and utilizing post-mortem samples of brains from patients with Alzheimer’s disease, found that a single event of a moderate-to-severe traumatic brain injury (TBI) can disrupt proteins that regulate an enzyme associated with Alzheimer’s. The paper, published in The Journal of Neuroscience, identifies the complex mechanisms that result in a rapid and robust post-injury elevation of the enzyme, BACE1, in the brain. These results may lead to the development of a drug treatment that targets this mechanism to slow the progression of Alzheimer’s disease.

25 Jul 2012

Children missing out on in battle against TB

The number of children diagnosed with tuberculosis only represents the tip of the iceberg, according to the University of Sydney’s Associate Professor Ben Marais, a specialist in childhood tuberculosis writing in the latest issue of The New England Journal of Medicine.

25 Jul 2012

Pediatrics News and Research

Latest Pediatrics News and Research

New insight into why glioblastoma multiforme recurs in adults

Researchers discover genetic process that can restore function to a CF defective protein

Pediatric liver transplant recipients have increased risk of death when from obese donors

Teplizumab type I diabetes prevention study now enrolls younger children

Tips on how to keep children safe during extreme hot weather

Obesity and heart disease risk in children: an interview with Joana Kist-van Holthe

GenomePooling™ method is sensitive and accurate

Kids with congenital heart defect should receive early evaluation for developmental disorders

Psychological abuse can be as damaging to young child's health as a slap, punch or kick

ATP1A3 gene mutations responsible for alternating hemiplegia of childhood

Enoxaparin prevents PVT in advanced cirrhosis

Sunovion launches ZETONNA Nasal Aerosol for allergic rhinitis

Researchers discover gene mutations in patients with alternating hemiplegia of childhood

Childhood physical and sexual abuse may increase risk of early or late onset menarche

Fusion of FGFR and TACC gene leads to glioblastoma

Brown fat fuels fight against obesity

Child who received first stem cell trachea transplant functioning well two years on

Excess maternal iodine supplementation can lead to congenital hypothyroidism in infants

Single event of brain trauma can lead to Alzheimer’s

Children missing out on in battle against TB

Exploring the role of confocal-based high-content imaging in advancing core facilities

Transforming Cardiovascular Care: Insights from Mina Makar at AstraZeneca

Clue's CEO Rhiannon White on the Future of Femtech and PCOS

Pediatrics News and Research

Latest Pediatrics News and Research

Exploring the role of confocal-based high-content imaging in advancing core facilities

Transforming Cardiovascular Care: Insights from Mina Makar at AstraZeneca

Clue's CEO Rhiannon White on the Future of Femtech and PCOS

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