Pharmacology News and Research

Latest Pharmacology News and Research

Diabetes drug fails to show any benefit against pancreatic cancer

A diabetes drug that showed promise in previous studies as an anti-cancer treatment failed to show any benefit in a UNC Lineberger Comprehensive Cancer Center-led study that used pancreatic cancer tissue samples to test sensitivity to the drug.

20 Jan 2016

New blood biomarkers could lead to better evaluation of treatment for patients with PAH

New blood biomarkers reflecting vasoreactivity in lung blood vessels of patients with heart- and lung disease, can lead to simplified diagnostics and better evaluation of treatment for patients with the condition pulmonary arterial hypertension (PAH).

18 Jan 2016

Researchers reveal biological connection between obesity and colorectal cancer risk

Obesity has long been associated with increased risk of colorectal cancer, but the link has never been understood. Now, a research team led by investigators at Thomas Jefferson University has revealed the biological connection, and in the process, has identified an approved drug that might prevent development of the cancer.

18 Jan 2016

Discoveries could lead to development of novel therapies to prevent C. diff infection

Researchers at Vanderbilt University Medical Center have obtained the crystal structure of a toxin from the bacterium Clostridium difficile ("C. diff") -- the leading cause of hospital-acquired diarrhea in the United States.

12 Jan 2016

Sage Analytics establishes distribution network in South America

Sage Analytics, the developers of portable, laboratory-quality cannabis potency measurement systems, announced it established a distribution network in South America, anchored by Senses Biotech in Uruguay.

11 Jan 2016

New strategy may reduce growth of pancreatic cancers in patients with KRAS gene mutation

University of North Carolina Lineberger Comprehensive Cancer Center researchers have found a promising strategy that may limit the growth of pancreatic cancers in patients with a mutation in a gene called KRAS.

11 Jan 2016

Salk Institute scientists find new target for glioblastoma multiforme treatment

Glioblastoma multiforme is a particularly deadly cancer. A person diagnosed with this type of brain tumor typically survives 15 months, if given the best care. The late Senator Ted Kennedy succumbed to this disease in just over a year.

11 Jan 2016

New injectable agent can potentially increase surgeon's ability to remove cancerous tumor during surgery

Doctors at the Duke University School of Medicine have tested a new injectable agent that causes cancer cells in a tumor to fluoresce, potentially increasing a surgeon's ability to locate and remove all of a cancerous tumor on the first attempt. The imaging technology was developed through collaboration with scientists at Duke, the Massachusetts Institute of Technology and Lumicell Inc.

7 Jan 2016

E-cigarettes share similar short-term safety profile as Nicorette products

A new study, published in the Journal of Regulatory Toxicology and Pharmacology, found that e-cigarettes share a similar short-term safety profile as Nicorette products and are comparable in reducing tobacco withdrawal symptoms.

7 Jan 2016

Scientists develop a method for cell replacement in diseased vessels

In industrialized countries, a particularly high number of people suffer from arteriosclerosis -- with fatal consequences: Deposits in the arteries lead to strokes and heart attacks. A team of researchers under the leadership of the University of Bonn has now developed a method for guiding replacement cells to diseased vascular segments using nanoparticles.

7 Jan 2016

Vanderbilt-led study questions about reporting genetic results to patients

A genetic test that suggests a patient may be at increased risk for potentially fatal heart rhythms is very often not as ominous as it sounds.

6 Jan 2016

Using antidepressant drug during first trimester of pregnancy may increase risk of birth defects

Using paroxetine--a medication prescribed to treat conditions including depression, obsessive-compulsive disorder, anxiety and posttraumatic stress disorder--during the first trimester of pregnancy may increase newborns' risk of congenital malformations and cardiac malformations. That's the conclusion of a recent analysis published in the British Journal of Clinical Pharmacology.

6 Jan 2016

Drug-microbe interactions may contribute to adverse effects, lessen effectiveness of NSAID

A nonsteroidal anti-inflammatory drug (NSAID) changed the composition and diversity of gut microbes, which in turn shaped how the drug is broken down and ultimately, cut its effectiveness, according to an animal study from the Perelman School of Medicine at the University of Pennsylvania.

5 Jan 2016

Antiscarring paste can halt fibrosis caused by radiation treatment

An antiscarring paste when applied to the skin of mice halts fibrosis caused by the radiation used in cancer therapy. That is according to a study led by researchers at Laura and Isaac Perlmutter Cancer Center to be published tomorrow in the January edition of the Journal of the Federation of American Societies for Experimental Biology, or FASEB.

5 Jan 2016

New guide provides valuable, unique overview of key properties of different drug targets

The new Concise Guide to PHARMACOLOGY 2015/2016 provides a valuable and unique overview of the key properties of more than 1,700 human drug targets, focusing on those exploited currently in the clinic or with future therapeutic potential.

5 Jan 2016

Researchers identify new gene that helps maintain chromosome number in cells

Molecular biologists at UT Southwestern Medical Center have identified a gene called NORAD that helps maintain the proper number of chromosomes in cells, and that when inactivated, causes the number of chromosomes in a cell to become unstable, a key feature of cancer cells.

26 Dec 2015

Researchers identify liver-derived hormone that regulates sugar intake

We all love our sugar, especially during the holidays. Cookies, cake, and candy are simply irresistible. While sugar cravings are common, the physiological mechanisms that trigger our "sweet tooth" are not well defined.

24 Dec 2015

ABC/VEN-analysis presents simple and effective method towards rational use of medicines

Rational use of medicines remains to be one of the most challenging problems in health systems worldwide. Kazan Federal University researchers conducted a practical study to assess the impact of introducing evidence-based principles to the practice of medicine procurement in order to manage budget expenditures on medicines of a multidisciplinary health facility for the period of 2011-2014.

23 Dec 2015

Personalised approach may help identify patients’ response to certain cancer treatments

Many people in Russia know about the Dima Rogachev Centre - particularly those who have faced the challenge of child cancer.

23 Dec 2015

Zinc levels in breast milk may help identify breast-feeding problems

Zinc levels in breast milk may be able to serve as an indicator of breast function during lactation, according to Penn State health researchers.

23 Dec 2015

Pharmacology News and Research

Latest Pharmacology News and Research

Diabetes drug fails to show any benefit against pancreatic cancer

New blood biomarkers could lead to better evaluation of treatment for patients with PAH

Researchers reveal biological connection between obesity and colorectal cancer risk

Discoveries could lead to development of novel therapies to prevent C. diff infection

Sage Analytics establishes distribution network in South America

New strategy may reduce growth of pancreatic cancers in patients with KRAS gene mutation

Salk Institute scientists find new target for glioblastoma multiforme treatment

New injectable agent can potentially increase surgeon's ability to remove cancerous tumor during surgery

E-cigarettes share similar short-term safety profile as Nicorette products

Scientists develop a method for cell replacement in diseased vessels

Vanderbilt-led study questions about reporting genetic results to patients

Using antidepressant drug during first trimester of pregnancy may increase risk of birth defects

Drug-microbe interactions may contribute to adverse effects, lessen effectiveness of NSAID

Antiscarring paste can halt fibrosis caused by radiation treatment

New guide provides valuable, unique overview of key properties of different drug targets

Researchers identify new gene that helps maintain chromosome number in cells

Researchers identify liver-derived hormone that regulates sugar intake

ABC/VEN-analysis presents simple and effective method towards rational use of medicines

Personalised approach may help identify patients’ response to certain cancer treatments

Zinc levels in breast milk may help identify breast-feeding problems

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Pharmacology News and Research

Latest Pharmacology News and Research

Pittcon Highlights: Pharmaceutical & Biologic eBook

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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