Pharmacology News and Research

Latest Pharmacology News and Research

Caregivers more aware of SUDEP than patients

Sudden unexpected death in epilepsy (SUDEP) is concerning and many—even those with seizure disorders—may not be aware of this condition. New research published in Epilepsia, a journal published by Wiley on behalf of the International League Against Epilepsy (ILAE), reports that 76% of caregivers are more likely to have heard of SUDEP compared with 65% of patients with epilepsy.

16 Oct 2014

Treeway, LACDR join forces to optimize clinical trial designs, data-analysis for ALS

Treeway and LACDR at the University of Leiden join forces and form a collaboration focused on the optimization of clinical trial designs and data-analysis for ALS (Amyotrophic Lateral Sclerosis) through the use of population disease progression models.

16 Oct 2014

Broccoli sprout compound may help ease classic behavioral symptoms in people with autism

Results of a small clinical trial suggest that a chemical derived from broccoli sprouts — and best known for claims that it can help prevent certain cancers — may ease classic behavioral symptoms in those with autism spectrum disorders (ASDs).

15 Oct 2014

$Researchers reveal gene variants that delay fracture healing$

Researchers reveal gene variants that delay fracture healing

Slow-healing or non-healing bone fractures in otherwise healthy people may be caused by gene variants that are common in the population, according to Penn State College of Medicine researchers.

15 Oct 2014

Preventing cancer: an interview with Dr Fiona Reddington

It’s estimated that more than four in 10 cancer cases could be prevented by lifestyle changes, such as not smoking, keeping a healthy body weight, cutting back on alcohol, eating a healthy diet, keeping active and staying safe in the sun.

13 Oct 2014

Study reveals inner workings of PKA switch that regulates cellular functions, contributes to deadly disorders

A University of Utah-led study using X-rays and neutron beams has revealed the inner workings of a master switch that regulates basic cellular functions, but that also, when mutated, contributes to cancer, cardiovascular disease and other deadly disorders.

13 Oct 2014

Blocking STAT3 in immune system cells increases anti-tumour immunity

The STAT transcription factors are involved in the development of many forms of cancer. STAT3 is frequently activated in tumour cells, so drugs targeting STAT3 could be used in cancer therapy. However, STAT3 is also important in the development of the immune system. Dagmar Gotthardt and colleagues at the Vetmeduni Vienna now show that blocking STAT3 in cells of the immune system actually leads to increased anti-tumour immunity. Anti-STAT3 therapy may thus be highly promising.

13 Oct 2014

Hormone loss may cause colon cancer, say Thomas Jefferson University researchers

Some cancers, like breast and prostate cancer, are driven by hormones such as estrogen and testosterone, but to date, there are none that are driven by the lack of a hormone. New evidence suggests that human colon cells may become cancerous when they lose the ability to produce a hormone that helps the cells maintain normal biology. If verified by further studies, it suggests that treating patients at high risk for colon cancer by replacing the hormone guanylin could prevent the development of cancer.

12 Oct 2014

New UCLA study reveals why people with autism experience neural stem cell overgrowth after birth

People with autism spectrum disorder often experience a period of accelerated brain growth after birth. No one knows why, or whether the change is linked to any specific behavioral changes.

10 Oct 2014

Researchers reveal new information about Protein Kinase A

Using X-rays and neutron beams, a team of researchers from the University of California, San Diego School of Medicine, University of Utah and Oak Ridge National Laboratory have teased out new information about Protein Kinase A (PKA), a ubiquitous master switch that helps regulate fundamental cellular functions like energy consumption and interactions with hormones, neurotransmitters and drugs.

10 Oct 2014

Molecular biologists awarded NIH grant to identify new compounds to fight malaria parasite

A team of molecular biologists, jointly led by Clemson University professor Jim Morris, was awarded a $151,121 grant from the National Institutes of Health to identify new compounds with anti-malarial activity for a deadly parasite species that kills hundreds of thousands of people each year.

9 Oct 2014

NIH announces high-risk, high-reward grants for UCSF researchers

UC San Francisco researchers received five awards announced this week by the National Institutes of Health (NIH) for high-risk, high-reward scientific research projects. Their work will focus on novel approaches for diagnosing and treating diseases ranging from autoimmune and chronic inflammatory diseases, to cancer, diabetes and neurological disorders.

8 Oct 2014

Case Western Reserve researcher lands Director's New Innovator Awards from NIH

For the second consecutive year, a Case Western Reserve University School of Medicine researcher has landed one of the year's much-coveted Director's New Innovator Awards from the National Institutes of Health. Principal investigator Rong Xu, PhD, assistant professor of medical informatics, will receive $2,377,000 for five years, starting immediately, to initiate computational analysis of thousands of drugs and their effects.

8 Oct 2014

'Achilles heel' in metabolic pathway could stop growth of lung cancer cells

Researchers at UT Southwestern Medical Center have found an "Achilles heel" in a metabolic pathway crucial to stopping the growth of lung cancer cells.

8 Oct 2014

UCSF researchers receive five NIH awards for high-risk scientific research projects

UC San Francisco researchers received five awards announced this week by the National Institutes of Health for high-risk, high-reward scientific research projects. Their work will focus on novel approaches for diagnosing and treating diseases ranging from autoimmune and chronic inflammatory diseases, to cancer, diabetes and neurological disorders.

8 Oct 2014

Many US patients with liver cancer do not receive proper treatment

Many US patients with liver cancer-even those with early stage disease that can often be cured-do not receive treatment for their disease, according to an analysis of studies published between 1989 and 2013.

6 Oct 2014

New method for extracting potential bone-producing cells from human fat

Within our fat lives a variety of cells with the potential to become bone, cartilage, or more fat if properly prompted. This makes adipose tissue, in theory, a readily available reservoir for regenerative therapies such as bone healing if doctors can get enough of those cells and compel them to produce bone.

6 Oct 2014

Modified form of niclosamide drug may hold key to battling type 2 diabetes

Type 2 diabetes affects an estimated 28 million Americans according to the American Diabetes Association, but medications now available only treat symptoms, not the root cause of the disease.

6 Oct 2014

Open payments database debuts, detailing financial connections between physicians and drug makers

Consumer advocates have pushed for years for this kind of government database in an effort to protect against physicians' conflicts of interest, to safeguard patient care and to prevent unnecessary costs to public health programs.

1 Oct 2014

Managing diabetes and intensive exercise: an interview with Dr Rafael Castol, Team Novo Nordisk

Team Novo Nordisk is a professional cycling team that races at UCI Pro Continental level. It's the first ever team to be made up of athletes diagnosed with Type 1 diabetes. The team was created three years ago, and is part of the Changing Diabetes initiative developed by Novo Nordisk.

From Novo Nordisk 1 Oct 2014

Pharmacology News and Research

Latest Pharmacology News and Research

Caregivers more aware of SUDEP than patients

Treeway, LACDR join forces to optimize clinical trial designs, data-analysis for ALS

Broccoli sprout compound may help ease classic behavioral symptoms in people with autism

Researchers reveal gene variants that delay fracture healing

Preventing cancer: an interview with Dr Fiona Reddington

Study reveals inner workings of PKA switch that regulates cellular functions, contributes to deadly disorders

Blocking STAT3 in immune system cells increases anti-tumour immunity

Hormone loss may cause colon cancer, say Thomas Jefferson University researchers

New UCLA study reveals why people with autism experience neural stem cell overgrowth after birth

Researchers reveal new information about Protein Kinase A

Molecular biologists awarded NIH grant to identify new compounds to fight malaria parasite

NIH announces high-risk, high-reward grants for UCSF researchers

Case Western Reserve researcher lands Director's New Innovator Awards from NIH

'Achilles heel' in metabolic pathway could stop growth of lung cancer cells

UCSF researchers receive five NIH awards for high-risk scientific research projects

Many US patients with liver cancer do not receive proper treatment

New method for extracting potential bone-producing cells from human fat

Modified form of niclosamide drug may hold key to battling type 2 diabetes

Open payments database debuts, detailing financial connections between physicians and drug makers

Managing diabetes and intensive exercise: an interview with Dr Rafael Castol, Team Novo Nordisk

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Pharmacology News and Research

Latest Pharmacology News and Research

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How can microdialysis benefit drug development

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