Pharmacology News and Research

Latest Pharmacology News and Research

Hypertension variability during cardiac surgery may increase risk of death

For patients with hypertension undergoing heart surgery, large variations in blood pressure before, during, and after the operation are associated with an increased risk of death, reports the July issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society.

24 Jun 2011

Research offers avenue for creating Alzheimer's and HIV therapeutics

A new advance by UCLA biochemists has brought scientists one step closer to developing treatments that could delay the onset of Alzheimer's disease and prevent the sexual transmission of HIV.

24 Jun 2011

New research helps explain how memories are stored at synapses

Have a tough time remembering where you put your keys, learning a new language or recalling names at a cocktail party? New research from the Lisman Laboratory at Brandeis University points to a molecule that is central to the process by which memories are stored in the brain. A paper published in the June 22 issue of the Journal of Neuroscience describes the new findings.

24 Jun 2011

Celerion generates over 25,000 platelet aggregation samples, achieves major milestone

Celerion, the premier provider of innovative early stage drug development solutions, announces it has achieved a major milestone of generating over 25,000 platelet aggregation sample results.

22 Jun 2011

Research focuses on how marijuana affects decision-making process

Smoking marijuana affects peoples' impulsivity, attention, memory, cognition and decision-making abilities. That's been scientifically proven.

22 Jun 2011

Neuroscientists to discuss future of mental health treatments at NCDEU meeting

More than 1,000 of the world's leading neuroscientists gathered this week at the 51st Annual NCDEU Meeting to discuss the future of mental health treatments.

21 Jun 2011

Perceptive's Clinical Trial Management System now available as SaaS application

Perceptive Informatics, a leading eClinical solutions provider and a subsidiary of PAREXEL International Corporation, today announced that its Clinical Trial Management System is available as an on-demand, software-as-a-service (SaaS) application.

From Parexel 20 Jun 2011

Targeting activity of PKD1 may be beneficial for treatment of polycystic kidney, liver disease

A single gene is central in the development of several forms of polycystic kidney and liver disease, Yale School of Medicine researchers report in the June 19 issue of Nature Genetics.

20 Jun 2011

Genomic study identifies MCU that regulates calcium transport into mitochondria

Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, and collaborators at Massachusetts General Hospital (MGH), the Broad Institute, and the David H. Koch Institute for Integrative Cancer Research at the Massachusetts Institute of Technology (MIT), today announced new findings published in Nature.

20 Jun 2011

Biomedical engineers analyze and duplicate the neural mechanism of learning in rats

Scientists have developed a way to turn memories on and off-literally with the flip of a switch. Using an electronic system that duplicates the neural signals associated with memory, they managed to replicate the brain function in rats associated with long-term learned behavior, even when the rats had been drugged to forget.

17 Jun 2011

Scientists uncover how immune system responds to invading anthrax bacteria

Scientists at the University of California, San Diego School of Medicine and Skaggs School of Pharmacy and Pharmaceutical Sciences have uncovered how the body's immune system launches its survival response to the notorious and deadly bacterium anthrax.

17 Jun 2011

Researchers reveal why anti-androgen therapy may fail in men with prostate cancer

Cancer is crafty. When one avenue driving its growth is blocked by drugs targeting that path, the malignancy often creates a detour, finding an alternative route to get around the roadblock.

16 Jun 2011

Boehringer Ingelheim, Zealand Pharma partner to develop Type-2 diabetes and obesity agonists

Today, Zealand Pharma, a Copenhagen based biopharmaceutical company, and Boehringer Ingelheim, one of the world's leading pharmaceutical companies, jointly announced an exclusive global licence and collaboration agreement for dual-acting glucagon and GLP-1 receptor agonists for the treatment of patients with Type-2 diabetes and patients with obesity.

16 Jun 2011

Alkermes commences ALKS 5461 phase 1/2 study for treatment-resistant depression

Alkermes, Inc. today announced the initiation of a phase 1/2 study of ALKS 5461 for treatment-resistant depression (TRD). ALKS 5461 is the combination of ALKS 33, a proprietary opioid modulator, and buprenorphine. TRD, which is also known as refractory depression, refers to depressive episodes that are not adequately controlled by standard antidepressant therapy.

15 Jun 2011

Scientists zero in on dose levels of "sacred mushroom"

Scientists at the Johns Hopkins University School of Medicine have zeroed in on the dose levels of the "sacred mushroom" chemical capable of yielding positive, life-changing experiences, while minimizing the chance of transient negative reactions in screened volunteers under supportive, carefully monitored conditions.

15 Jun 2011

Researchers reveal how anti-arrhythmic drugs control irregular heartbeats

University of British Columbia researchers - using an innovative, atom-by-atom substitution method - have uncovered the mechanism by which a particular class of drugs controls irregular heartbeats.

15 Jun 2011

Jamieson introduces UC-II undenatured collagen to relieve osteoarthritis pain

Most people think that arthritis is an inevitable part of aging. Today, Jamieson Laboratories has introduced UC-II undenatured collagen, a formulation that will turn back the clock on joint pain by naturally promoting the restoration of cartilage and inhibiting its deterioration. This new anti-aging formula taken only once daily is proven to be twice as effective as other joint remedies.

15 Jun 2011

Research reveals how humans of different ancestry process polyunsaturated fat

Over the past decade, much progress has been made regarding the understanding and promise of personalized medicine. Scientists are just beginning to consider the impact of gene-diet interactions in different populations in regards to disease prevention and treatment.

15 Jun 2011

Celerion earns ANVISA certification to conduct clinical research operations in Belfast, Lincoln

Celerion, the premier provider of innovative early stage drug development solutions, is pleased to announce that its clinical research operations in Belfast, Northern Ireland UK, and its clinical research and bioanalytical services operations in Lincoln, Nebraska USA, have been certified by the Brazilian National Health Surveillance Agency.

9 Jun 2011

Metabolomics analysis shows 3IS as early predictive, sensitive biomarker of acute kidney injury

Metabolon, Inc., the leader in metabolomics, biomarker discovery and analysis, announces the publication of "Metabolomics Analysis Reveals Elevation of 3-Indoxyl Sulfate in Plasma and Brain during Chemically-induced Acute Kidney Injury in Mice: Investigation of Nicotinic Acid Receptor Agonists", in Toxicology and Applied Pharmacology.

9 Jun 2011