Pharmacology News and Research

Latest Pharmacology News and Research

Intellect obtains pharmacokinetic data from OX1 Phase 1b trial for Alzheimer's disease

Intellect Neurosciences, Inc., a biopharmaceutical company with an internal preclinical and clinical-stage pipeline and multiple licenses with major pharmaceutical companies covering products in late-stage clinical trials, announced that it has obtained a draft pharmacokinetic report from its completed Phase 1b trial for its lead Alzheimer's candidate, OX1. The Company previously reported on the safety aspects of the trial, which demonstrated that OX1 is safe and well tolerated at all dose levels tested.

28 Dec 2010

Paternal diet affects lipid metabolizing genes in offspring

Scientists at the University of Massachusetts Medical School and the University of Texas at Austin have uncovered evidence that environmental influences experienced by a father can be passed down to the next generation, "reprogramming" how genes function in offspring. A new study published this week in Cell shows that environmental cues-in this case, diet-influence genes in mammals from one generation to the next, evidence that until now has been sparse.

24 Dec 2010

Scientists pinpoint brain site where leptin hormone may trigger onset of puberty

UT Southwestern Medical Center researchers have pinpointed a tiny site in the brain where the hormone leptin may help trigger the onset of puberty.

23 Dec 2010

MCP-1 protein may contribute to failure of AV fistulas created for vascular access in dialysis patients

A protein implicated in the development of vascular diseases may also contribute to the failure of arteriovenous (AV) fistulas created for vascular access in dialysis patients, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN).

23 Dec 2010

Merck announces FDA approval for GARDASIL against HPV-related anal cancer

Merck, known as MSD outside the United States and Canada, announced today that the U.S. Food and Drug Administration (FDA) has approved GARDASIL® [Human Papillomavirus Quadrivalent (Types 6, 11, 16, and 18) Vaccine, Recombinant] for the prevention of anal cancer caused by human papillomavirus (HPV) types 16 and 18 and for the prevention of anal intraepithelial neoplasia (AIN) grades 1, 2 and 3 (anal dysplasias and precancerous lesions) caused by HPV types 6, 11, 16 and 18, in males and females 9 through 26 years of age.

23 Dec 2010

Certain drugs may block tumor host interactions but do not destroy cancer cells

A class of drugs thought to kill cancer cells may in fact block "cross talk" between the cancer cell and normal immune cells, resulting in reduced cancer growth and spread-a discovery that could significantly alter the way cancer drugs are evaluated in the future.

23 Dec 2010

Patients with over expression of P-Rex1 protein are more likely to develop cancer metastasis

Overexpression or hyperactivation of ErbB cell-surface receptors drives the growth of many breast cancers. Drugs, like Herceptin, that block the receptors' signals halt tumor progression in some patients.

23 Dec 2010

NCI grants U-M Cancer Center $10.7M for study of colorectal and pancreatic cancer

The University of Michigan Comprehensive Cancer Center has received a five-year $10.7 million grant from the National Cancer Institute to study colorectal and pancreatic cancer.

23 Dec 2010

NIH Clinical Center opens doors to Damon Runyon Clinical Investigators

A new pilot partnership between the National Institutes of Health Clinical Center, the National Cancer Institute's Center for Cancer Research, and the Damon Runyon Cancer Research Foundation will offer some of the capabilities and expertise of America's research hospital to an external group of clinical investigators in cancer research. The special talent and resources of the NIH will allow Damon Runyon-funded investigators to undertake studies and collaborations that will advance understanding of the prevention, diagnosis, and treatment of cancer.

22 Dec 2010

Spinal Botox injection reduces pain

Botulinum neurotoxin type A (BoNT/A)—better known as Botox—reduces responses to an inflammation-related pain stimulus when injected into the spinal canal in mice, reports a study in the January issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society (IARS).

22 Dec 2010

Contamination with potential disease-causing bacteria is commonly found on hands of anesthesia providers

Contaminating bacteria are very commonly found on the hands of anesthesia providers, with high rates of transmission to the surgical field during operations, reports a study in the January issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society.

22 Dec 2010

Whites with mutations more likely to be susceptible to cocaine abuse

Nearly one in five whites could carry a genetic variant that substantially increases their odds of being susceptible to severe cocaine abuse, according to new research.

21 Dec 2010

Researchers present definitive explanation of how fibrotic cells destroy human liver

In the latest of a series of related papers, researchers at the University of California, San Diego School of Medicine, with colleagues in Austria and elsewhere, present a new and more definitive explanation of how fibrotic cells form, multiply and eventually destroy the human liver, resulting in cirrhosis. In doing so, the findings upend the standing of a long-presumed marker for multiple fibrotic diseases and reveal the existence of a previously unknown kind of inflammatory white blood cell.

21 Dec 2010

New research sheds light on complex regulatory pathways for effective innate immune system

New research by scientists at the University of California, San Diego School of Medicine and Skaggs School of Pharmacy and Pharmaceutical Sciences reveals that the immune system has an effective backup plan to protect the body from infection when the "master regulator" of the body's innate immune system fails.

21 Dec 2010

Lilly Endowment grants funds to Manchester College to establish School of Pharmacy

A small Midwest college that is producing alumni with sizeable reputations in the science world has received a $35 million grant from Lilly Endowment to launch a School of Pharmacy.

21 Dec 2010

Clue to the blues that come with the flu

Vanderbilt University researchers may have found a clue to the blues that can come with the flu - depression may be triggered by the same mechanisms that enable the immune system to respond to infection.

21 Dec 2010

NanoLogix enters collaboration with Advanced Medical German Company of Kuwait

NanoLogix, an innovator in the accelerated detection and identification of microorganisms, is pleased to announce its collaboration with Advanced Medical German Company of Kuwait (AMGKWT). This alliance will support NanoLogix's market penetration goals for the Middle East, North and East Africa with the international marketing focus of Advanced Medical German Company stretching from the Middle East through Africa.

20 Dec 2010

Chelsea completes successful NORTHERA pre-NDA assessment with FDA

Chelsea Therapeutics International, Ltd. announced it has completed a pre-NDA assessment with the U.S. Food and Drug Administration (FDA) and intends to accelerate its new drug application (NDA) for NORTHERA™(droxidopa) for the treatment of symptomatic, neurogenic orthostatic hypotension (NOH), a chronic and potentially debilitating drop in blood pressure upon standing commonly associated Parkinson's disease, multiple system atrophy and pure autonomic failure.

20 Dec 2010

Scientists suggest targeting ion channels could offer effective pain relief

University at Buffalo neuroscience researchers conducting basic research on ion channels have demonstrated a process that could have a profound therapeutic impact on pain.

20 Dec 2010

NIAID renews funding of PRIME to develop mathematical models to study influenza infection

Mount Sinai School of Medicine today announced that the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, has renewed funding of the Program for Research on Immune Modeling and Experimentation. This program seeks to develop easy-to-use, predictive mathematical models to better understand patterns of infection among individuals affected by the H1N1 and 1918 influenza viruses and other related viruses.

17 Dec 2010

Pharmacology News and Research

Latest Pharmacology News and Research

Intellect obtains pharmacokinetic data from OX1 Phase 1b trial for Alzheimer's disease

Paternal diet affects lipid metabolizing genes in offspring

Scientists pinpoint brain site where leptin hormone may trigger onset of puberty

MCP-1 protein may contribute to failure of AV fistulas created for vascular access in dialysis patients

Merck announces FDA approval for GARDASIL against HPV-related anal cancer

Certain drugs may block tumor host interactions but do not destroy cancer cells

Patients with over expression of P-Rex1 protein are more likely to develop cancer metastasis

NCI grants U-M Cancer Center $10.7M for study of colorectal and pancreatic cancer

NIH Clinical Center opens doors to Damon Runyon Clinical Investigators

Spinal Botox injection reduces pain

Contamination with potential disease-causing bacteria is commonly found on hands of anesthesia providers

Whites with mutations more likely to be susceptible to cocaine abuse

Researchers present definitive explanation of how fibrotic cells destroy human liver

New research sheds light on complex regulatory pathways for effective innate immune system

Lilly Endowment grants funds to Manchester College to establish School of Pharmacy

Clue to the blues that come with the flu

NanoLogix enters collaboration with Advanced Medical German Company of Kuwait

Chelsea completes successful NORTHERA pre-NDA assessment with FDA

Scientists suggest targeting ion channels could offer effective pain relief

NIAID renews funding of PRIME to develop mathematical models to study influenza infection

Pittcon Highlights: Pharmaceutical & Biologic eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Pharmacology News and Research

Latest Pharmacology News and Research

Pittcon Highlights: Pharmaceutical & Biologic eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Newsletters you may be interested in