Pharmacology News and Research

Latest Pharmacology News and Research

Study can serve as basis for developing new approaches for obesity, diabetes

In the 21st century, the search for methods of treating noncommunicable diseases, such as obesity, metabolic syndrome, and diabetes are among the top priorities.

24 Apr 2020

Scientists are developing synthetic COVID-19 antibody to treat sick patients

A team of researchers at the Icahn School of Medicine at Mount Sinai, in collaboration with GenScript, is developing a synthetic antibody to SARS-CoV-2, the virus that causes coronavirus disease (COVID-19). This antibody is intended to block the virus from entering human lung cells, and would be another potential treatment option for COVID-19.

24 Apr 2020

Study: JNK and BNP activity can reverse cardiovascular damage, reduce risk of death from sepsis

Overreaction is rarely useful, and in the case of the human immune system, it can be outright deadly. When the body overreacts to an infection, the result is sepsis - a life-threatening condition that frequently leads to acute organ dysfunction, including deterioration of the heart and blood vessels, which make up the cardiovascular system.

24 Apr 2020

A protein discovery could pave way to better treatments for obesity

A USC-led international team of scientists has found the precise shape of a key player in human metabolism, which could lead the way to better treatments for obesity and other metabolic disease.

23 Apr 2020

Combinations of PAC and WFA are highly synergistic against proliferation of non-small cell lung cancer

Oncotarget Volume 11 Issue 16 showed that the sensitivity of H1299 and A549 cells to concomitant treatment with PAC and WFA was greater than that of either PAC or WFA alone.

23 Apr 2020

COST Action creates “Task Force” of researchers to contribute to Covid-19 research

STRATAGEM COST Action (New diagnostic and therapeutic tools against multidrug resistant tumors) has created a "Task Force" of researchers contributing to Covid-19 research.

23 Apr 2020

Study reveals potential therapeutic target for treating cocaine addiction

A new study explains how cocaine modifies functions in the brain revealing a potential target for therapies aimed at treating cocaine addiction.

22 Apr 2020

Study: Orujo Olive OIL reduces obesity and inflammatory complications in obese mice

Researchers from the Department of Pharmacology, Paediatrics and Radiology at the University of Seville, in collaboration with Dr. Rodriguez from the International University of Catalonia, have confirmed that Orujo Olive OIL (POCTA), when introduced into the diet, produces a significant reduction in obesity and vascular and inflammatory complications in obese mice.

22 Apr 2020

Coumarin derivatives are synthesized using green chemistry methods

Coumarin derivatives (coumarins) are a class of compounds with a wide range of biological activities, which have found their application in medicine, pharmacology, cosmetics and food industry. Coumarin is found in a number of plants such as tonka beans and vanilla grass, among others.

21 Apr 2020

Discovery could open door to the development of new anti-cancer drugs

A team of scientists led by the University of Michigan Rogel Cancer Center and Case Comprehensive Cancer Center has identified the binding site where drug compounds could activate a key braking mechanism against the runaway growth of many types of cancer.

20 Apr 2020

Using genome-wide CRISPR technology to identify leukemia's weakness

A team of researchers at University of California San Diego School of Medicine and Moores Cancer Center used CRISPR technology to identify key regulators of aggressive chronic myeloid leukemia, a type of cancer that remains difficult to treat and is marked by frequent relapse.

20 Apr 2020

Penn Medicine launches convalescent plasma therapy trial for COVID-19 patients

Convalescent plasma therapy for COVID-19 patients -- an experimental approach of giving a transfusion of plasma collected from a donor who has recovered from COVID-19 to a patient with an active infection -- is the focus of a new two-part research initiative at Penn Medicine.

20 Apr 2020

Activating a braking mechanism against cancer

A team has identified the binding site where drug compounds could activate a braking mechanism against runaway growth of cancer.

20 Apr 2020

Scientists discover anti-cancer compound in the humble willow

More than a century after giving the world aspirin, another potential drug has been found in the stem and leaves of willows – this time with anti-cancer properties.

17 Apr 2020

Regular exercise may reduce risk of deadly complication in patients with COVID-19

Regular exercise may reduce the risk of acute respiratory distress syndrome, a major cause of death in patients with the COVID-19 virus, a top exercise researcher reports.

15 Apr 2020

Researchers decode how immune sensor plays role in defending cells against intruders

Until now, the immune sensor TLR8 has remained in the shadows of science. A research team led by the University of Bonn has now discovered how this sensor plays an important role in defending human cells against intruders.

15 Apr 2020

Harnessing power of cancer gene could lead to first curative treatment for heart disease

Researchers trying to turn off a gene that allows cancers to spread have made a surprising U-turn. By making the gene overactive and functional in the hearts of mice, they have triggered heart cell regeneration.

15 Apr 2020

Temple researchers receive NIAID grant to study immunological synapse formation

Switching immune cells on is a critical step in combating infection. In the case of T cells, which are key players in immunity, this happens when dormant T cells circulating in the blood encounter a suspicious agent on the surface of specialized antigen-presenting cells.

14 Apr 2020

WVU researchers develop viable alternatives to N95 masks

The novel coronavirus pandemic has nearly exhausted stockpiles of medical gear in the United States. Personal protective equipment, like masks, serve as a first-line defense for medical professionals with a front row seat to COVID-19.

13 Apr 2020

Mechanical ventilators based on a simple modification of CPAP and BiPAP machines

As hospitals in New York City and beyond are facing a shortage of mechanical ventilators for COVID-19 patients in critical care, many are turning to readily available CPAP and BiPAP machines as a measure.

10 Apr 2020