Pharmacology News and Research

Latest Pharmacology News and Research

Sick mitochondria pollute the cells, cause telomere damage

Researchers at UPMC Hillman Cancer Center provide the first concrete evidence for the long-held belief that sick mitochondria pollute the cells they're supposed to be supplying with power.

27 Aug 2019

Researchers discover new way to stop inflammation in the lungs due to sepsis, injury

University of Calgary researchers at the Cumming School of Medicine (CSM) led by Drs. Donna Senger, PhD, Paul Kubes, PhD, and Stephen Robbins, PhD have discovered a new way to stop harmful inflammation in the lungs due to sepsis and injury.

25 Aug 2019

Head-to-head comparison of three breast cancer drugs reveals important differences

Every year, more than 250,000 women in the U.S. are diagnosed with breast cancer. When detected early, patients with the most common form--which tests positive for hormone receptors (HR+) and negative for the HER2 receptor--usually respond well to treatment.

23 Aug 2019

Study uncovers cause of asthmatic lung spasms

Researchers at Rutgers and other institutions have discovered how muscle contraction (bronchospasm) in the airway, which cause breathing difficulty in people with asthma, occur by creating a microdevice that mimics the behavior of the human airways.

22 Aug 2019

Study opens up a new way for developing potential glioblastoma treatment

A team led by Texas A&M University's College of Veterinary Medicine & Biomedical Sciences' researcher Dr. Stephen Safe has discovered a new pathway that may help suppress the development of glioblastoma tumors, one of the deadliest forms of cancer.

22 Aug 2019

Changes to mitochondria drive inflammation in type 2 diabetes, not glucose

To date, the underlying causes of inflammation in obesity and type 2 diabetes mellitus have been poorly understood, which has hampered efforts to develop treatments to prevent complications from a disease that is the third leading cause of death in the United States.

21 Aug 2019

SLU researchers receive $2.1 million to find non-addictive pain medications

Neuropathic pain affects between 15 and 20 million people in the U.S. This type of pain can occur after injuries to the nervous system due to trauma, disease or exposure to neurotoxins, including after chemotherapy.

19 Aug 2019

Binge drinking may cause more damage to women than men

Alcohol consumption is a major cause of chronic liver disease in the United States, and binge drinking is emerging as a significant contributor to liver injury.

19 Aug 2019

Study finds no harm to newborns from opioid maintenance treatment during pregnancy

A new Pharmacology Research & Perspectives study found no harm to newborns from opioid maintenance treatment (OMT) during pregnancy compared with no treatment.

16 Aug 2019

Removal of a critical enzyme may help cases of sepsis finds research

Scientists at the University of California San Diego School of Medicine have shown that removal of an enzyme called the PH domain Leucine-rich repeat Protein Phosphatase 1 (PHLPP1) could help laboratory mice with sepsis in a model they had created for their experiment. The study titled, “PHLPP1 counter-regulates STAT1-mediated inflammatory signalling,” was published this week in the journal eLife.

15 Aug 2019

Joint lubricating fluid triggers pain response from nerve cells in osteoarthritic patients

A team at the University of Cambridge has shown how, in osteoarthritis patients, the viscous lubricant that ordinarily allows our joints to move smoothly triggers a pain response from nerve cells similar that caused by chilli peppers.

14 Aug 2019

Resurrecting protein ancestors yields evolutionary insights into their role in human cells

"Resurrecting" the ancestors of key proteins yields evolutionary insights into their role in human cells and in most cancers, a new study finds.

14 Aug 2019

Removing single enzyme improves outcomes in mouse model of sepsis

Sepsis occurs when the body goes overboard in its attempt to fight off an infection. Immune cells rush in, overreact and wreak havoc on tissues and organs, often resulting in organ failure and death.

14 Aug 2019

Roswell Park receives more than $15 million in grants for cancer research

Roswell Park Comprehensive Cancer Center researchers have received more than a dozen recent grant awards totaling more than $15.4 million.

14 Aug 2019

Latest advances in cardiovascular medicine to be unveiled

Journalists looking to stay abreast of the hottest research in cardiology are invited to follow the press program for ESC Congress 2019, this year held together with the World Congress of Cardiology.

13 Aug 2019

Three new early-career investigators join federally funded precision medicine initiative

Three new early-career investigators have been selected to be a part of the University of Kansas Medical Center's $11.5 million precision medicine-focused federal grant.

9 Aug 2019

Study evaluates the effect of smoking status on disease outcomes in ulcerative colitis

Because smokers are less likely to develop ulcerative colitis, a type of inflammatory bowel disease, patients with UC may be tempted to start smoking to lessen their symptoms.

7 Aug 2019

Researchers discover promising approach to silence HIV infection

Researchers from The University of Texas Medical Branch at Galveston have discovered a new potential medication that works with an HIV-infected person's own body to further suppress the ever present but silent virus that available HIV treatments are unable to combat.

6 Aug 2019

Study examines the utility of thyroid function screening in youth with mood and anxiety disorders

A new study from researchers at the University of Cincinnati and Cincinnati Children's looks at the prevalence of abnormal thyroid function in youth with severe mood and anxiety disorder.

6 Aug 2019

Scientists can now control neural circuits using smartphone

A team of scientists in Korea and the United States have invented a device that can control neural circuits using a tiny brain implant controlled by a smartphone.

5 Aug 2019