Pharmacology News and Research

Latest Pharmacology News and Research

Mutations in folliculin gene affect embryo implantation

New information is unfolding on the genetic controls of an early turning point in pregnancy. As the tiny, dividing cell mass, the blastocyst, travels from the oviduct and lodges in the wall of the uterus, the cells must exit their pre-implantation state and be ready for post-implantation development.

7 Feb 2019

New review examines impact of cancer therapies on the skeleton

A new British Journal of Clinical Pharmacology review examines the impact of cancer therapies on the skeleton and how to limit bone loss and fractures in cancer patients treated with these therapies.

6 Feb 2019

Cannabinoid compounds may reduce viability of colon cancer cells

Medical marijuana has gained attention in recent years for its potential to relieve pain and short-term anxiety and depression. Now, Penn State College of Medicine researchers say some cannabinoid compounds may actually inhibit the growth of colon cancer cells in the lab.

6 Feb 2019

Researchers describe first case of patient affected by dysfunctions in SLC28 gene family

A research team has described the first case of a patient affected by dysfunctions in a nucleoside transporter of the SLC28 gene family, which brings a set of genes which were not related to human pathologies in the scientific bibliography so far.

5 Feb 2019

Researchers identify treatable mechanism in patients with schizophrenia

For reasons that are unclear, schizophrenia patients have fewer connections between the neurons in the brain. Researchers at Karolinska Institutet, Sweden, and Massachusetts General Hospital, USA, have now succeeded in creating human cell models that show that there is an excessive degradation of connections in the brain of these patients, and they have been able to link this to a genetic risk variant for the disease.

4 Feb 2019

New approach helps clinicians to decide most effective antibiotic treatment courses

A scientific team from Case Western Reserve University School of Medicine and Cleveland Clinic has developed a new way to identify second-line antibiotics that may be effective in killing germs already resistant to a first-line antibiotic - potentially helping overcome antibiotic resistance.

31 Jan 2019

New apprenticeship scheme set to support Life Sciences Industrial Strategy of the UK government

Approval has been granted for the development of a new national apprenticeship standard for the role of clinical pharmacology scientist, thanks to a cross-sector drive to address the skills gap.

31 Jan 2019

Novel therapeutic approach for treatment of leukemia

The BCR/ABL gene, which does not occur among healthy people, has been shown to be a causative agent in the pathogenesis of B-cell acute lymphocytic leukemia.

24 Jan 2019

Research provides new insights into why we crave fatty foods when dieting

Have you ever wondered why we crave the very foods that we try to avoid when dieting? Or wish there was a way to turn off the craving?

24 Jan 2019

Telephone follow-up by pharmacists benefits patients after hospital discharge

A new British Journal of Clinical Pharmacology study illustrates the benefits of having clinical pharmacists follow up, by telephone, with patients at risk of having medication-related issues after hospital discharge. The aim is to help patients manage their medications effectively.

24 Jan 2019

Overprescribing of antidepressants may occur more often in elderly patients

In a Pharmacology Research & Perspectives study of individuals living in Olmsted County, Minnesota from 2005–2012, potential overprescribing of antidepressant medications occurred in nearly one-quarter of elderly residents.

24 Jan 2019

Synthetic compound from flaxseed can improve heart function in mice with sepsis

Sepsis is a life-threatening systemic inflammatory condition that develops in response to infection. One of its major complications is cardiovascular dysfunction, in which deterioration of the heart muscle, driven by decreased energy production resulting from reduced oxygen and nutrient supplies, frequently ends in organ failure.

23 Jan 2019

Scientists discover a dramatic pattern of bone growth in female mice

UCLA and UC San Francisco life scientists have discovered a dramatic pattern of bone growth in female mice -- research that could potentially lead to stronger bone density in women and new treatments for osteoporosis in older women.

18 Jan 2019

Scientists design two AI algorithms to improve early detection of cognitive impairment

Researchers of the Pharmacy and Mathematics departments of the CEU UCH university in Valencia have collaborated in the design of two artificial intelligence algorithms that improve the screening of positive cases in the early detection of cognitive impairment in chemists.

17 Jan 2019

How Patch Clamp Technology Can Benefit Ion Channel Research

Learn how patch clamp technology meets high-throughput to benefit ion channel research in this interview with Tim and James, Nanion.

From Nanion Technologies 16 Jan 2019

High Quality Purification of Proteins Through Liquid Chromatography

In this interview, AZoNetwork speaks to Knauer about the use of FPLC for purification of proteins and how their products enable scientists to get the most of liquid chromatography; conducted by Matthew Rafferty

From KNAUER Wissenschaftliche Geräte GmbH 15 Jan 2019

Scientists identify endogenous activator of sigma-1 receptors in human cells

Cells communicate through complex mechanisms that typically involve receptors and ligands that bind to them. Endogenous ligands, produced by the body, have been identified for the vast majority of cellular receptors, helping explain receptor existence and function. But in the case of sigma-1 receptors, which interact with a diverse array of psychoactive drugs, an endogenous ligand has remained elusive.

14 Jan 2019

Study raises hopes for new approaches to treat osteoporosis

A handful of brain cells deep in the brain may play a surprising role in controlling women's bone density, according to new research by UC San Francisco and UCLA scientists.

11 Jan 2019

New findings bring about better understanding of many cancers' metabolic needs

Scientists at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have discovered that squamous cell skin cancers do not require increased glucose to power their development and growth, contrary to a long-held belief about cancer metabolism.

10 Jan 2019

Exposure to cannabis, stress during adolescence may lead to long-term anxiety disorders

A new study conducted on laboratory animals shows that exposure to cannabis and stress during adolescence may lead to long-term anxiety disorders characterized by the presence of pathological fear.

8 Jan 2019