Pharmacology News and Research

Latest Pharmacology News and Research

Scientists identify three new distinct breast epithelial cell populations

Researchers from the University of California, Irvine School of Medicine, in collaboration with scientists at UCSF and Northwestern University, have profiled human breast epithelial cells, identifying three new distinct epithelial cell populations.

1 Jun 2018

Researchers reveal role NAD+ molecule in turning on genes that make fat cells

Glucose is the energy that fuels cells, and the body likes to store glucose for later use. But too much glucose can contribute to obesity, and scientists have long wanted to understand what happens within a cell to tip the balance.

1 Jun 2018

Study proposes a new way to reverse the aging process

A new discovery about the effects of aging in our cells could allow doctors to cure or prevent diabetes, fatty liver disease and other metabolic diseases - and possibly even turn back the clock on aging itself.

29 May 2018

Exercise alters brain's dopamine system to help treat addiction, study finds

New research by the University at Buffalo Research Institute on Addictions has identified a key mechanism in how aerobic exercise can help impact the brain in ways that may support treatment -; and even prevention strategies -; for addiction.

25 May 2018

SLU researcher aims to find solutions for diabetes patients at risk of hypoglycemia

A $150,000 grant from The Leona M. and Harry B. Helmsley Charitable Trust will support research at Saint Louis University led by scientist Gina Yosten, Ph.D. Yosten's team is pursuing solutions for people with diabetes who are at risk of life-threatening drops in blood sugar known as hypoglycemia.

25 May 2018

Home-based telehealth therapy program effective for stroke rehabilitation, shows study

In-home rehabilitation, using a telehealth system and supervised by licensed occupational/physical therapists, is an effective means of improving arm motor status in stroke survivors, according to findings presented by University of California, Irvine neurologist Steven C. Cramer, MD, at the recent 2018 European Stroke Organisation Conference in Gothenburg, Sweden.

24 May 2018

Study identifies new mechanism involved in development of Lou Gehrig's disease

A new Tel Aviv University study identifies a previously unknown mechanism involved in the development of Lou Gehrig's disease, or amyotrophic lateral sclerosis.

23 May 2018

Medication-related harm found to be common among older adults, but preventable

New research indicates that harm from medicines is common in older adults following hospital discharge, and it results in substantial use of healthcare resources.

23 May 2018

UCI research team uncovers new unexpected mode of neurotransmitter-based communication

Researchers at the University of California, Irvine School of Medicine have discovered the first example of a novel mode of neurotransmitter-based communication.

22 May 2018

Researchers reveal mechanisms of periodic paralysis in people with rare genetic disorder

A rare genetic disorder in which people are suddenly overcome with profound muscle weakness is caused by a hole in a membrane protein that allows sodium ions to leak across cell membranes, researchers at the University of Washington School of Medicine in Seattle have found.

21 May 2018

Researchers create tool to determine patient's response to immunotherapy drugs

Understanding that not all bladder cancers are the same, researchers at the University of North Carolina Lineberger Comprehensive Cancer Center have created a tool that may help them to uncover why only a fraction of patients respond to new immune-based treatments.

21 May 2018

AACN brings together over thousands of nurses for annual conference

The American Association of Critical-Care Nurses brings together thousands of nurses this week in Boston at its annual National Teaching Institute & Critical Care Exposition with the theme "Guided by Why."

21 May 2018

Study provides insights into how immune cells kill bacteria with acid

The first line of immune defense against invading pathogens like bacteria are macrophages, immune cells that engulf every foreign object that crosses their way. After enclosing it in intracellular membrane vesicles, a process called phagocytosis, macrophages kill their prey with acid.

17 May 2018

New study reveals the extent of brain damage due to elevated homocysteine

The amino acid homocysteine occurs naturally in the human body, generated as a byproduct of methionine metabolism.

17 May 2018

Researchers to explore how to prevent stress-related chronic pain conditions

More than 50 million people in the United States suffer from pain in the absence of injury. This includes patients with migraines, fibromyalgia, irritable bowel syndrome and many other disorders.

15 May 2018

Acetaminophen use helps reduce acute kidney injury risk in pediatric heart surgery patients

Children who underwent cardiac surgery were less likely to develop acute kidney injury if they had been treated with acetaminophen in the first 48 hours after their procedures, according to a Vanderbilt study just published in JAMA Pediatrics.

15 May 2018

Study uncovers promising new line of attack against aggressive prostate cancer

UC San Francisco researchers have discovered a promising new line of attack against lethal, treatment-resistant prostate cancer. Analysis of hundreds of human prostate tumors revealed that the most aggressive cancers depend on a built-in cellular stress response to put a brake on their own hot-wired physiology.

14 May 2018

Research may pave way for new C. diff antitoxins and anti-cancer drugs

Researchers from the University of California, Irvine and Harvard University have discovered how the Clostridium difficile toxin B recognizes the human Frizzled protein, the receptor it uses to invade intestinal cells and lead to deadly gastrointestinal infections.

14 May 2018

Researchers screen molecules that could be potential target for prostate cancer treatments

Cancer researchers at the University of Bath have measured systematically how efficient molecules are at suppressing the activity of a protein associated with prostate and other cancers. The molecules could eventually be developed into new anti-cancer drugs.

14 May 2018

Study finds inappropriate prescriptions given to many older adults discharged from hospital

In a British Journal of Clinical Pharmacology study of 259 older adults discharged from a general medical hospital, more than 4 in 5 patients were issued a potentially inappropriate prescription containing at least 1 potentially inappropriate medication or potential prescribing omission.

11 May 2018