Pharmacology News and Research

Latest Pharmacology News and Research

New 'lymphoma micro-reactor' device targets chemo-resistant tumors

Non-Hodgkin lymphoma, a cancer that is diagnosed in the U.S. more than 70,000 times annually, arises from overly proliferating immune cells within the body's lymph nodes, which are connected to a network of lymph vessels through which lymphatic fluid flows.

12 Apr 2018

Study reveals unexpected mechanism that induces thirst after alcohol or sugar exposure

Why does drinking alcohol or consuming sugar make us thirsty? An international study of mice in Texas and humans in Europe reveals an unexpected anti-dehydration mechanism.

12 Apr 2018

UCLA scientists identify four subtypes of melanoma with different drug sensitivities

Melanoma, a relatively rare but deadly skin cancer, has been shown to switch differentiation states - that is, to regress to an earlier stage of development - which can lead it to become resistant to treatment.

12 Apr 2018

Scientists developing new vaccines against heroin and prescription opioids

Heroin and prescription opioid abuse and fatal overdoses are a public health emergency in the United States. Vaccines offer a potential new strategy to treat opioid abuse and prevent fatal opioid overdoses.

12 Apr 2018

Finding new drug target for common form of lung cancer

Research by Rutgers Cancer Institute of New Jersey investigators has identified novel functions of the superoxide dismutase 1 (SOD1) enzyme providing support that it could serve as a therapeutic target in the most common type of lung cancer.

10 Apr 2018

Popular e-cigarette flavors produce different levels of toxins

The flavor of an e-cigarette may affect more than a consumer's taste buds, according to Penn State researchers who say the chemicals that make up different flavors also produce different levels of free radicals, toxins often associated with cancer and other diseases.

9 Apr 2018

Researchers find link between common genetic variant and AFib risk in Latinos

"There is a paradox at play when it comes to atrial fibrillation in the Latino population," said Dr. Dawood Darbar.

9 Apr 2018

Experts explore how degenerative processes impair the body's detoxification system

A poor diet and other risk factors can result in liver disease. This important metabolic organ can become fatty and inflamed. In the long term, this may result in irreversible and life-threatening organ damage (cirrhosis of the liver or 'shrunken liver').

9 Apr 2018

Nosopharm and UIC reveal pharmacology of new class of antibiotics to combat drug resistance

Nosopharm, a company dedicated to the research and development of new anti-infective drugs, and the University of Illinois at Chicago today announce the publication of a study in Molecular Cell on the mechanism of action of odilorhabdins, a new class of antibiotics to combat antibiotic resistance.

9 Apr 2018

Free Radical Formation in Electronic Cigarette Aerosols

An interview with Prof. John Richie, describing his presentation at Pittcon 2018 on free radical formation in electronic cigarette aerosols.

From Pittcon 5 Apr 2018

Analysis does not reveal consistent link between NSAIDs use and exacerbation of inflammatory bowel disease

Contrary to generally accepted belief, a recent review and analysis of published studies did not reveal a consistent association between the use of nonsteroidal anti-inflammatory drugs (NSAIDs) or acetaminophen and exacerbation of Crohn's disease and ulcerative colitis.

5 Apr 2018

Sulfur amino acid restriction consistently demonstrates range of health benefits in animals

The longevity and health improvements seen in animals on sulfur amino acid-restricted diets could translate to people, according to Penn State College of Medicine researchers who recently conducted a review of published studies. More research is needed to confirm the benefits in people, the scientists said.

4 Apr 2018

Human genome is like a time machine, says researcher

The human genome is a bit like a time machine, says Ben Voight, an associate professor in Systems Pharmacology and Translational Therapeutics and of Genetics in Penn's Perelman School of Medicine.

3 Apr 2018

Long-term consumption of caffeine has negative effects for Alzheimer's disease

A study coordinated by the Institute of Neuroscience of the Universitat Autònoma de Barcelona and in collaboration with the Karolinska Institutet in Sweden provides evidence that a long-term consumption of caffeine has negative effects for Alzheimer's disease, worsening the neuropsychiatric symptoms appearing in the majority of those affected by the disorder. The research was recently published in Frontiers in Pharmacology.

3 Apr 2018

Research pinpoints potential weak link in bacterial wall-building protein

The wall that surrounds bacteria to shield them from external assaults has long been a tantalizing target for drug therapies. Indeed, some of modern medicine's most reliable antibiotics disarm harmful bacteria by disrupting the proteins that build their protective armor.

28 Mar 2018

Phase I clinical trial of HIV vaccines to begin in the U.S.

A Phase I clinical trial testing the safety of vaccines that might have the potential to prevent HIV infection will begin this month at four sites in the United States, marking the latest step in a three-decade quest at UMass Medical School to harness the power of DNA vaccines in addressing a major global health threat.

28 Mar 2018

Study uncovers more complex, elaborate role for the body’s macromolecular complexes

Scientists at the National Institute on Drug Abuse Intramural Research Program have uncovered evidence that shows a more complex and elaborate role for the body's hard-working G protein-coupled receptors than previously thought, suggesting a conceptual advance in the fields of biochemistry and pharmacology.

28 Mar 2018

Research highlights methods to identify antibiotic related kidney damage in children with CF

New research, published in Nature Scientific Reports, conducted by the University and partners highlights effective methods for identifying a common side effect in children receiving drug treatments for Cystic fibrosis.

28 Mar 2018

Scientists demonstrate successful implementation of prosthetic memory system

Scientists at Wake Forest Baptist Medical Center and the University of Southern California (USC) have demonstrated the successful implementation of a prosthetic system that uses a person's own memory patterns to facilitate the brain's ability to encode and recall memory.

28 Mar 2018

MSU scientists test promising drug to prevent cancer in high-risk patients

Michigan State University scientists are testing a promising drug that may stop a gene associated with obesity from triggering breast and lung cancer, as well as prevent these cancers from growing.

27 Mar 2018