Post Traumatic Stress Disorder (PTSD) News and Research

Latest Post Traumatic Stress Disorder (PTSD) News and Research

Neuralstem commences dosing in NSI-189 Phase Ib trial for major depressive disorder

Neuralstem, Inc. announced that the first patients were dosed in Phase Ib of its ongoing trial to test the safety of NSI-189 in the treatment of major depressive disorder (MDD).

25 Jun 2012

Study examines protective factors that are important in preventing violence among veterans

A national survey identifies which U.S. military veterans may be at most risk of aggression after deployment and what strategies could potentially help reduce likelihood of violence when service members return home.

25 Jun 2012

One in eight people with heart attack experience significant symptoms of PTSD

One in eight people who suffer a heart attack or other acute coronary event experience clinically significant symptoms of post-traumatic stress disorder (PTSD), according to a meta-analysis of 24 studies led by Columbia University Medical Center researchers.

21 Jun 2012

Tips for how to help someone with PTSD

You don't have to be a member of the armed forces to have post-traumatic stress disorder (PTSD), but nearly 20 percent of service members deployed to Iraq and Afghanistan reported having symptoms. In recognition of June as PTSD Awareness Month, Wounded Warrior Project (WWP) is offering 10 tips for how to help someone who may be suffering from PTSD.

16 Jun 2012

Researchers use brain imaging to uncover susceptibility to psychological stress and trauma

Most people have intense emotional reactions to traumatizing events like road accidents or combat. But some suffer far longer, caught in the grip of long-term debilitating disorders such as Post-Traumatic Stress Disorder (PTSD). Because doctors cannot predict who will develop these disorders, however, early or preventive intervention is not available. Now, a new project led by researchers at Tel Aviv University seeks to identify pre-traumatic subjects - those who are more susceptible to long-standing disorders if exposed to a traumatic incident.

14 Jun 2012

Experimental drug and genetic differences indicate how people deal with fear and stress

Researchers at Duke University and the National Institutes of Health have found a way to calm the fears of anxious mice with a drug that alters their brain chemistry. They've also found that human genetic differences related to the same brain chemistry influence how well people cope with fear and stress.

12 Jun 2012

D-cycloserine may increase response to PTSD psychotherapy

Posttraumatic stress disorder (PTSD) is among the most common, distressing, and disabling medical consequences of combat or other extremely stressful life events. The first-line treatment for PTSD is exposure therapy, a type of behavioral therapy where patients confront their fears in a safe environment. Although it is an effective treatment, many patients still experience symptoms after treatment and there is a relatively high drop-out rate.

5 Jun 2012

Interim data from UCLA and NeuroSigma’s eTNS Phase I trial on PTSD, MDD

Today, at the 52nd annual New Clinical Drug Evaluation Unit (NCDEU) Conference in Arizona, Ian Cook, M.D., Professor of Psychiatry at the University of California, Los Angeles (UCLA) and a Senior Medical Advisor to NeuroSigma, Inc., presented the results from the first 6-subject cohort of a 10-subject Phase I open-label clinical trial studying the effects of external trigeminal nerve stimulation (eTNS) on Post-Traumatic Stress Disorder (PTSD) and depressive symptoms in Major Depressive Disorder (MDD) as an adjunct to pharmacotherapy.

31 May 2012

Posttraumatic stress hits stroke secondary prevention

Patients who develop posttraumatic stress disorder after stroke or transient ischemic attack are at high risk for being nonadherent to secondary prevention medications, say researchers.

30 May 2012

Cautious optimism over prevalence of PTSD

A decade after the start of the wars in Afghanistan and Iraq, studies have shown that the incidence of post-traumatic stress disorder (PTSD) among troops is surprisingly low, and a Harvard researcher credits the drop, in part, to new efforts by the Army to prevent PTSD, and to ensure those who do develop the disorder receive the best treatment available.

18 May 2012

Human memory: how to improve yours

Many of us wish we had better memories: be it so that we can pass our exams; remember what to buy from the supermarket; or even remember what we went upstairs for!

16 May 2012

New clinical trial to evaluate effectiveness of ABMT for PTSD

At Ease USA, a Nebraska organization dedicated to providing confidential post-traumatic stress disorder (PTSD) care for military families, has launched a clinical trial of a promising new therapeutic intervention at Creighton University.

14 May 2012

Results reported for clinical trial for the treatment of depression using external trigeminal nerve stimulation

Earlier today, at the American Psychiatric Association Annual Meeting in Philadelphia, Dr. Ian Cook, Principal Investigator and Professor of Psychiatry at UCLA, and a Senior Medical Advisor to NeuroSigma, Inc., presented the results of a Phase Ib open-label clinical trial that studied the effects of eTNS™ on depressive symptoms in Major Depressive Disorder (MDD) as an adjunct to pharmacotherapy. Results from the 17-question Hamilton Depression Rating Scale (HDRS-17), a clinician-rated scale, showed a 50.0% reduction in depression and the Beck Depression Inventory (BDI), a self-reported scale, showed a 58.0% reduction in scores. Both scales achieved statistical significance. In the trial, subjects placed stimulating eTNS™ electrodes on their foreheads for 8 hours each night and their depression was measured every two weeks using recognized standard tests. eTNS was well tolerated and no serious adverse events occurred during the 8-week treatment period.

9 May 2012

New analysis on why some soldiers never seek PTSD care

U.S. Army researcher Maj. Gary H. Wynn, M.D., shared new analysis on why some Soldiers suffering from combat-related post-traumatic stress disorder (PTSD) never seek care or drop out of treatment early during a presentation today at the American Psychiatric Association's annual meeting. His presentation, "Epidemiology of Combat-Related PTSD in U.S. Service Members: Lessons Learned," also described the approaches the Army is using to address this issue and improve overall patient outcomes.

8 May 2012

Patterns of brain activity that play a role in recall of memories and decision-making

UCSF scientists have identified patterns of brain activity in the rat brain that play a role in the formation and recall of memories and decision-making. The discovery, which builds on the team's previous findings, offers a path for studying learning, decision-making and post-traumatic stress syndrome.

4 May 2012

HDAC6 protein may provide novel target for stress-linked disorders

A cellular protein called HDAC6, newly characterized as a gatekeeper of steroid biology in the brain, may provide a novel target for treating and preventing stress-linked disorders, such as depression and post-traumatic stress disorder (PTSD), according to research from the Perelman School of Medicine at the University of Pennsylvania.

24 Apr 2012

Veterans with killing experience more likely to report suicidal thoughts

The experience of killing in war was strongly associated with thoughts of suicide, in a study of Vietnam-era veterans led by researchers at the San Francisco VA Medical Center (SFVAMC) and the University of California, San Francisco.

19 Apr 2012

PTSD could be genetically predicted

PTSD can occur after any kind of experience that causes trauma, whether that be in war, after a natural disaster or because of child abuse or sexual assault. Symptoms can include flashbacks, feeling emotionally numb or hyper-alert to danger, and avoiding situations that act as reminders of the original trauma. It is estimated that up to 3% of the general population is likely to be affected by PTSD at some point.

5 Apr 2012

Scientists link two genes involved in serotonin production to PTSD

Why do some persons succumb to post-traumatic stress disorder (PTSD) while others who suffered the same ordeal do not? A new UCLA study may shed light on the answer.

2 Apr 2012

First study to examine link between cumulative traumatic stress exposure and inflammation

Greater lifetime exposure to the stress of traumatic events was linked to higher levels of inflammation in a study of almost 1,000 patients with cardiovascular disease led by researchers at the San Francisco VA Medical Center and the University of California, San Francisco.

30 Mar 2012