Primary Care News and Research

Latest Primary Care News and Research

Persons with narcolepsy with cataplexy have low levels of protein thought to help regulate sleep

Persons with narcolepsy with cataplexy have low levels of cerebrospinal fluid (CSF) hypocretin-1, a protein thought to help regulate sleep and wakefulness, according to a study published in the August 1st issue of the journal SLEEP.

2 Aug 2007

Biological markers of narcolepsy

The first report to identify the biological markers of narcolepsy using gene expression in white blood cells finds that the MX2 gene, which is relevant to the immune system, is significantly less expressed in narcoleptics compared with normal subjects.

2 Aug 2007

Babies born to mothers who smoked have higher systolic blood pressures

Infants whose mothers smoke during pregnancy have substantially higher blood pressures in their first months of life, Dutch researchers reported in Hypertension: Journal of the American Heart Association.

1 Aug 2007

Obese patients get patchy weight-loss support from their local health surgery

Only one in seven UK doctors’ surgeries provide well-developed support programmes for obese patients, according to a survey of primary care nurses published in the latest Journal of Advanced Nursing.

1 Aug 2007

Active management of risk in pregnancy lowers Cesarean rates

At a time when national rates of cesarean delivery have climbed above 30%, a four-year study of patients receiving an alternative method of obstetric care experienced a significantly lower rate of cesarean births, according to a study published in the current issue of the Annals of Family Medicine .

1 Aug 2007

Prescribing antibiotics to children remains common practice

Regular prescribing of antibiotics to children in the community is sufficient to sustain a high level of antibiotic resistance in the population, warn experts in a study published on bmj.com.

27 Jul 2007

Thiazolinediones increase risk of heart failure

A class of drugs commonly used to treat type 2 diabetes may double the risk of heart failure, according to a new analysis by researchers at Wake Forest University School of Medicine and colleagues.

27 Jul 2007

GPs antibiotic prescribing practices are still contributing to resistance

GPs are still prescribing antibiotics for up to 80% of cases of sore throat, otitis media, upper respiratory tract infections, and sinusitis, despite the fact that official guidance warns against this practice, according to an analysis of the world's largest primary care database of consultations and prescriptions, published this week in a supplement to the Journal of Antimicrobial Chemotherapy.

26 Jul 2007

Telephone counseling coaxes reluctant alcoholics into treatment

Telephone counseling might be an effective primary care intervention for men who are not seeking treatment for their alcohol dependence or abuse, according to a new study.

25 Jul 2007

Diabetes epidemic in New York City

The diabetes epidemic is taking a large and growing toll on New York City, a new Health Department report shows, as death rates, debilitating complications, and hospitalization costs soar.

25 Jul 2007

Inner-city Baltimore not safe for young kids

Infants and young children living in Baltimore's inner-city homes are at risk for serious perils, including fires, falls and poisoning, according to a small but revealing study from the Johns Hopkins Children's Center.

25 Jul 2007

Most patients satisfied with their GP's opening hours

Proof that GP practices are open at times to suit the vast majority of patients (84%) comes today (24 July 2007) ) with publication of results from the English Department of Health's GP Patient Survey.

24 Jul 2007

Restless legs syndrome simulator

Restless legs syndrome (RLS) remains a common, yet often undiagnosed, neurological sensorimotor disorder, despite many years of research and increased disease recognition.

20 Jul 2007

Giving patients question checklists helps patients ask right questions

Asking more questions during a visit to the doctor might help patients get care that is more satisfactory, but many patients are not sure where to start.

20 Jul 2007

Review of smoking cessation techniques

Some people are unwilling or unable to stop smoking, but are prepared to try and reduce the numbers of cigarettes they smoke each day.

18 Jul 2007

Quitting smoking with rimonabant

Using selective cannabinoid 1 (CB1) receptor antagonists such as rimonabant at a dose of 20 mg per day can help people quit smoking, can help them to remain abstinent, and can help prevent the weight gain that so often accompanies attempts at stopping smoking.

18 Jul 2007

Review examines how well GPs treat anxiety, depression or substance abuse

When patients have psychosocial problems such as anxiety, depression or substance abuse, a general practice doctor is often the first healthcare professional they see.

18 Jul 2007

2 week wait rule for breast cancer patients questioned

The "two week wait rule" is failing breast cancer patients and needs to be reviewed urgently say the authors of a seven year study examining the impact of the target, published on bmj.com.

13 Jul 2007

New target for muscular dystrophy drug therapy

Researchers at the University of Pennsylvania School of Medicine report how the gene for utrophin, which codes for a protein very similar to dystrophin, the defective protein in Duchenne muscular dystrophy (DMD), puts the brakes on its own expression in muscle cells, thereby suggesting a new target for treatment.

13 Jul 2007

Some smokers have genetic predisposition to develop chronic obstructive pulmonary disease

Some people have a genetic variation that makes them more susceptible to chronic obstructive pulmonary disease (COPD) if they smoke tobacco, according to new research from Wake Forest University School of Medicine and colleagues.

12 Jul 2007