Psoriasis

Psoriasis is a chronic, immune-mediated disease that results from the overproduction of skin cells, resulting in their accumulation on the surface of the skin, which causes red, scaly plaques that may itch and bleed. It is estimated that approximately 7.5 million Americans and nearly 3 percent of the world's population are living with psoriasis and nearly one-quarter of those people have cases that are considered moderate to severe.

What is Psoriasis?

Psoriasis represents a chronic inflammatory skin condition with a complex pathophysiology and significant genetic background.

Psoriasis Types

Psoriasis Treatment

Psoriasis Topical Treatment

Psoriasis Systemic Treatment

Psoriasis Prognosis

Psoriasis Phototherapy

Psoriasis Photochemotherapy

Psoriasis Historical Treatment

Psoriasis Genetic Factors

Psoriasis Epidemiology

Psoriasis Drug Development

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Psoriasis Diagnosis

Psoriasis Clinical Classification

What causes Psoriasis?

Psoriasis Alternative Therapy

Living With Psoriasis

Diet and Psoriasis

Latest Psoriasis News and Research

A genetic variant modulates interferon signaling and disease risk

For years, scientists have looked to a critical piece of immune system machinery - known as the interferon pathway - for answers. There, when our cells sense an infection, they release a protein known as interferon, which warns other cells to fight the virus.

13 Dec 2024

Women with premature ovarian insufficiency face higher risk of autoimmune diseases

Research reveals a significant association between premature ovarian insufficiency and autoimmune diseases, highlighting hypothyroidism as a common condition.

2 Dec 2024

Ultra-processed foods increase active psoriasis risk, study shows

This study highlights a significant link between high ultra-processed food (UPF) consumption and active psoriasis, independent of BMI and other factors. The findings emphasize UPFs' contribution to proinflammatory pathways in individuals with this chronic skin condition.

1 Dec 2024

Binghamton University joins groundbreaking $42.8 million inflammatory disease treatment project

Binghamton University will play a key role in a federal grant of up to $42.8 million to develop an implantable device that acts as a living pharmacy to treat inflammatory diseases.

5 Nov 2024

Vitiligo linked to increased risk of heart disease and stroke, study finds

Research indicates elevated cardiovascular risk in vitiligo patients, underscoring the necessity for enhanced monitoring and preventive healthcare measures.

29 Oct 2024

MALDI-TOF mass spectrometry proves effective for diagnosing onychomycosis in nail psoriasis

Nail psoriasis is common in patients with plaque psoriasis and is associated with morbidity, including onychomycosis, which can complicate psoriasis treatments and be difficult to differentiate.

26 Oct 2024

Research uncovers how parasitic worms evade itch response

Ever had an itchy nose or, worse, an unreachable spot on your back that drives you mad? Now imagine an itch that refuses to go away, no matter how hard or long you scratch.

26 Oct 2024

At-home phototherapy proves effective for psoriasis treatment

For decades, people with psoriasis have been treated in clinics with narrowband ultraviolet B phototherapy, or light therapy, to reduce sores, scales, and inflammation.

24 Oct 2024

Calluna Pharma successfully completes Phase 1 clinical study of CAL101, a first-in-class therapeutic for fibrotic and fibro-inflammatory indications

Calluna Pharma AS (Calluna), a clinical stage biotechnology company pioneering first-in-class antibodies to treat inflammatory and fibrotic diseases, today announced the completion of Phase 1 clinical study for CAL101, Calluna’s lead product candidate.

23 Oct 2024

Iron retention in skin linked to psoriasis: Could hepcidin be the missing piece in treatment?

This study reveals hepcidin's significant role in psoriasis, linking iron retention to inflammation and keratinocyte growth, suggesting new therapeutic targets.

1 Oct 2024

Hormone hepcidin identified as potential trigger for psoriasis

Scientists may have uncovered the root cause of psoriasis, a chronic and sometimes debilitating skin disease that affects 2-3% of the global population. The condition is characterized by red, scaly patches that impact the quality of a patient's life and can sometimes be life-threatening.

26 Sep 2024

Perceived stress can directly trigger psoriasis relapse

Innovative research has provided compelling evidence that perceived stress can directly trigger the relapse of psoriatic skin lesions. The study, presented today at the European Academy of Dermatology and Venereology (EADV) Congress 2024, is the first to scientifically validate this connection in vivo.

26 Sep 2024