Psoriasis

Psoriasis is a chronic, immune-mediated disease that results from the overproduction of skin cells, resulting in their accumulation on the surface of the skin, which causes red, scaly plaques that may itch and bleed. It is estimated that approximately 7.5 million Americans and nearly 3 percent of the world's population are living with psoriasis and nearly one-quarter of those people have cases that are considered moderate to severe.

What is Psoriasis?

Psoriasis represents a chronic inflammatory skin condition with a complex pathophysiology and significant genetic background.

Psoriasis Types

Psoriasis Treatment

Psoriasis Topical Treatment

Psoriasis Systemic Treatment

Psoriasis Prognosis

Psoriasis Phototherapy

Psoriasis Photochemotherapy

Psoriasis Historical Treatment

Psoriasis Genetic Factors

Psoriasis Epidemiology

Psoriasis Drug Development

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Psoriasis Diagnosis

Psoriasis Clinical Classification

What causes Psoriasis?

Psoriasis Alternative Therapy

Living With Psoriasis

Diet and Psoriasis

Latest Psoriasis News and Research

Binghamton University joins groundbreaking $42.8 million inflammatory disease treatment project

Binghamton University will play a key role in a federal grant of up to $42.8 million to develop an implantable device that acts as a living pharmacy to treat inflammatory diseases.

5 Nov 2024

Vitiligo linked to increased risk of heart disease and stroke, study finds

Research indicates elevated cardiovascular risk in vitiligo patients, underscoring the necessity for enhanced monitoring and preventive healthcare measures.

29 Oct 2024

MALDI-TOF mass spectrometry proves effective for diagnosing onychomycosis in nail psoriasis

Nail psoriasis is common in patients with plaque psoriasis and is associated with morbidity, including onychomycosis, which can complicate psoriasis treatments and be difficult to differentiate.

26 Oct 2024

Research uncovers how parasitic worms evade itch response

Ever had an itchy nose or, worse, an unreachable spot on your back that drives you mad? Now imagine an itch that refuses to go away, no matter how hard or long you scratch.

26 Oct 2024

At-home phototherapy proves effective for psoriasis treatment

For decades, people with psoriasis have been treated in clinics with narrowband ultraviolet B phototherapy, or light therapy, to reduce sores, scales, and inflammation.

24 Oct 2024

Calluna Pharma successfully completes Phase 1 clinical study of CAL101, a first-in-class therapeutic for fibrotic and fibro-inflammatory indications

Calluna Pharma AS (Calluna), a clinical stage biotechnology company pioneering first-in-class antibodies to treat inflammatory and fibrotic diseases, today announced the completion of Phase 1 clinical study for CAL101, Calluna’s lead product candidate.

23 Oct 2024

Iron retention in skin linked to psoriasis: Could hepcidin be the missing piece in treatment?

This study reveals hepcidin's significant role in psoriasis, linking iron retention to inflammation and keratinocyte growth, suggesting new therapeutic targets.

1 Oct 2024

Hormone hepcidin identified as potential trigger for psoriasis

Scientists may have uncovered the root cause of psoriasis, a chronic and sometimes debilitating skin disease that affects 2-3% of the global population. The condition is characterized by red, scaly patches that impact the quality of a patient's life and can sometimes be life-threatening.

26 Sep 2024

Perceived stress can directly trigger psoriasis relapse

Innovative research has provided compelling evidence that perceived stress can directly trigger the relapse of psoriatic skin lesions. The study, presented today at the European Academy of Dermatology and Venereology (EADV) Congress 2024, is the first to scientifically validate this connection in vivo.

26 Sep 2024

Cardiovascular disease pathways associated with psoriasis, but not other immune-mediated diseases

A genetic connection between cardiovascular disease and psoriasis highlights shared inflammatory pathways, emphasizing the need for cardiovascular monitoring.

19 Sep 2024

Monoclonal antibodies could help provide an answer to antimicrobial resistance

Monoclonal antibodies – treatments developed by cloning a cell that makes an antibody – could help provide an answer to the growing problem of antimicrobial resistance, say scientists.

16 Sep 2024

New insights on how melanoma cells resist cancer immunotherapy

Immune checkpoint inhibitors are cancer fighting drugs that help the immune system do its job of detecting and attacking tumor cells.

27 Aug 2024

Risankizumab outperforms ustekinumab in treating moderate-to-severe Crohn’s disease

Researchers compare the therapeutic efficacy of risakizumab and ustekinumab for the treatment of moderate-to-severe Crohn’s disease.

23 Aug 2024

Maintaining healthy weight could lower risk of immune-mediated skin diseases in kids

Childhood obesity can contribute to the development of common immune-mediated skin diseases (IMSDs), such as alopecia areata, atopic dermatitis, and psoriasis, new research finds.

21 Aug 2024

Novel molecular signaling pathway found to play a crucial role in maintaining the skin barrier

Our skin–the body's largest organ–provides the first line of defense against infections and many other threats to our health.

9 Aug 2024

Reduced folate intake enhances metabolic plasticity in aged mice

Folate fortification of staple foods has long been practiced in many countries.

6 Aug 2024

Pomegranate peel extract restores skin balance, fights infections

Pomegranate peel extract effectively restores skin microbiota balance by reducing Staphylococcus aureus and promoting Staphylococcus epidermidis growth, showcasing its potential as a non-toxic antimicrobial treatment.

5 Aug 2024

Long-term air pollution exposure doubles psoriasis risk, study finds

Long-term exposure to air pollution and genetic predisposition significantly increase the risk of developing psoriasis, highlighting the roles of both environmental and genetic factors.

17 Jul 2024

How Aloe vera's medicinal properties make it essential in medicine, cosmetics, and food products

Comprehensive review highlights Aloe vera's versatile biological activities and its potential applications in medicine and cosmetics while addressing its safety concerns.

11 Jul 2024

New method developed to map mechanistic connections between diseases

Tampere University researchers developed a method to map mechanistic connections between diseases, revealing deeper associations beyond traditional classifications based on affected organs and symptoms.

28 Jun 2024