Rheumatoid Arthritis News and Research

Latest Rheumatoid Arthritis News and Research

Arthritis drug wins approval for use in children with Crohn's disease

The Food and Drug Administration in the U.S. has given approval for the drug Remicade for use in children with active Crohn's disease(CD), a chronic and debilitating condition.

21 May 2006

New rheumatoid arthritis drugs may put patients at risk of infections and cancer

Anti-TNF (tumor necrosis factor) therapies are a tried and tested type of medication used for treating rheumatoid arthritis and the drugs provide benefit to many of thousands of patients worldwide.

21 May 2006

Study shows strong association between treatment with TNF-blocking antibodies and development of serious infections

A new meta-analysis of many previous studies of TNF- (tumor necrosis factor) blocking antibodies for treatment of rheumatoid arthritis has confirmed a previously discovered increased risk for serious infection and has found that cancer also is a potential risk associated with the drugs.

17 May 2006

Study holds promise for malarial susceptibility test

Cell and animal studies conducted jointly by scientists at Johns Hopkins, Yale and other institutions have uncovered at least one important contributor to the severe anemia that kills almost half of the 2 million people worldwide who die each year of malaria.

12 May 2006

$Childhood arthritis increases the risk of fractures$

Childhood arthritis increases the risk of fractures

Childhood arthritis increases the risk of fractures, particularly during adolescence, according to a large study of British patient records. The researchers say that more targeted treatments promoting bone health would benefit patients with childhood-onset arthritis throughout their lifespan.

8 May 2006

The efficacy and safety of Rituximab in patients with active rheumatoid arthritis

Drugs aimed at suppressing inflammation-provoking cytokines--specifically those linked to T-cells--have improved the treatment of rheumatoid arthritis (RA), a chronic, inflammatory autoimmune disease. Still, the frequency of remission achieved by these biologic agents remains below 50 percent.

3 May 2006

Etanercept and chemo might reduce fatigue in cancer patients

Researchers here have found evidence that combining a drug typically used to treat rheumatoid arthritis with chemotherapy might help reduce fatigue and muscle wasting that often afflicts cancer patients.

3 May 2006

Drug combo significantly more effective in reducing dyspepsia in arthritis patients

UCLA/VA researchers found that for arthritis patients, taking a combination of two drugs may be most effective in protecting against stomach upset called dyspepsia, which is a side effect of common pain medications.

3 May 2006

Study indicates how drug efficacy can be increased by manipulating the signalling mechanism

Researchers believe they have found a way to change the action of 60 percent of currently available medications, in some cases making them many times more effective, according to an article published in the April 21 edition of the journal Science. The discovery has the potential to improve treatments for diseases including heart disease, cancer, diabetes, depression and arthritis. The study describes a new way to manipulate perhaps the most important signaling mechanism in human cells: G-protein coupled receptors (GPCRs).

28 Apr 2006

Enhancing the function of the protein SOCS3 could be a more effective way to regulate cell responses

A discovery made at The Walter and Eliza Hall Institute provides new insights into enhancing the function of the protein SOCS3, which regulates the response of cells to external stimuli.

26 Apr 2006

Discovery points to more effective ways of regulating cell signalling

A discovery made at The Walter and Eliza Hall Institute provides new insights into enhancing the function of the protein SOCS3, which regulates the response of cells to external stimuli.

20 Apr 2006

217 new targets for anti-cancer drugs

By identifying novel genes critical to cancer progression, biologists at the U.S. Department of Energy's Argonne National Laboratory have expanded the number of drug targets researchers have available for study to find ways to stop tumors in their tracks.

18 Apr 2006

First evidence that circulating endothelial microparticles lead to heart valve disease

Under normal physiological conditions, low levels of microparticles are continually being shed into the blood from the endothelium - the cells that line the inside of blood vessels and some organs -and appear to cause no problems.

13 Apr 2006

Study assesses formularies across Medicare drug plans

Medicare's new private stand-alone drug plans vary significantly - in terms of covered drugs, out-of-pocket costs for specific medications, and restrictions placed on the use of certain drugs - according to a new analysis released today by the Kaiser Family Foundation.

11 Apr 2006

Drug trial disaster will discourage future volunteers

According to the British government agency responsible for medical safety, the Medicines and Healthcare Products Regulatory Agency (MHRA), no evidence has been found to suggest there were any problems with the manufacturing of a drug which left six volunteers seriously ill.

6 Apr 2006

MIT look at how cells make life-or-death decisions

The biological processes underlying diseases such as rheumatoid arthritis and cancer are fundamentally linked, and should be linked in how they are treated with drugs, a series of MIT studies indicates.

6 Apr 2006

Targeting the inflamed synovium: The quest for specificity

In the April 2006 issue of Arthritis & Rheumatism, noted rheumatology specialists with Kings College London, Dr. Toby Garrood and Dr. Costantino Pitzalis offer an overview of recent breakthroughs and a preview of future directions in this critical quest for specificity.

4 Apr 2006

Targeting of angiogenic endothelial cells at sites of inflammation by Dexamethasone Phosphate-containing RGD peptide liposomes inhibits experimental arthritis

Vascular endothelial cells (VECs) form the walls of blood vessels and play a critical role in inflammation.

4 Apr 2006

Remicade (infliximab) gains Australian approval for treatment of early rheumatoid arthritis

Schering-Plough Corporation today announced that the Therapeutic Goods Administration of the Department of Health and Ageing in Australia has revised the indication of Remicade (infliximab) to include the treatment of early rheumatoid arthritis (RA) and approved a new indication for psoriatic arthritis (PsA).

23 Mar 2006

Stem cells, gene therapy and allograft applications show promise for treating orthopaedic conditions

Recent advances in gene therapy, stem cells and other promising applications are offering new hope for patients and helping orthopaedic surgeons provide state-of-the-art treatment for various frame-related conditions.

23 Mar 2006

Rheumatoid Arthritis News and Research

Latest Rheumatoid Arthritis News and Research

Arthritis drug wins approval for use in children with Crohn's disease

New rheumatoid arthritis drugs may put patients at risk of infections and cancer

Study shows strong association between treatment with TNF-blocking antibodies and development of serious infections

Study holds promise for malarial susceptibility test

Childhood arthritis increases the risk of fractures

The efficacy and safety of Rituximab in patients with active rheumatoid arthritis

Etanercept and chemo might reduce fatigue in cancer patients

Drug combo significantly more effective in reducing dyspepsia in arthritis patients

Study indicates how drug efficacy can be increased by manipulating the signalling mechanism

Enhancing the function of the protein SOCS3 could be a more effective way to regulate cell responses

Discovery points to more effective ways of regulating cell signalling

217 new targets for anti-cancer drugs

First evidence that circulating endothelial microparticles lead to heart valve disease

Study assesses formularies across Medicare drug plans

Drug trial disaster will discourage future volunteers

MIT look at how cells make life-or-death decisions

Targeting the inflamed synovium: The quest for specificity

Targeting of angiogenic endothelial cells at sites of inflammation by Dexamethasone Phosphate-containing RGD peptide liposomes inhibits experimental arthritis

Remicade (infliximab) gains Australian approval for treatment of early rheumatoid arthritis

Stem cells, gene therapy and allograft applications show promise for treating orthopaedic conditions

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Rheumatoid Arthritis News and Research

Latest Rheumatoid Arthritis News and Research

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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