Schizophrenia

Schizophrenia is a chronic debilitating disorder which affects more than two million Americans, and millions more worldwide. While significant progress has been made in understanding the disease and developing treatments, there remains a significant unmet medical need. More than 50% of patients switch their medication in a given year due to either poor response or the experience of adverse events.

Schizophrenia

Schizophrenia is a chronic mental health disorder that causes people to think, feel and perceive the world differently from the general population.

Schizophrenia Diagnosis

Schizophrenia Causes

Schizophrenia Signs and Symptoms

Schizophrenia Neural Processes

Schizophrenia Mechanisms

Schizophrenia Screening, Prevention and Management

Schizophrenia Medication

Schizophrenia Interventions

Schizophrenia Prognosis

Latest Schizophrenia News and Research

Single dose IV iron shows promise in treating anemia during pregnancy

Anemia during pregnancy is a common occurrence and often due to iron deficiency. It is a global public health problem, affecting an estimated 37 percent of pregnant individuals, according to the World Health Organization.

31 Jan 2025

Study identifies contrast perception deficit in people with schizophrenia

Schizophrenia is a serious mental disorder that affects around 1% of the world's population. Researchers of the University of Barcelona have identified a deficit in contrast perception in people with schizophrenia.

28 Jan 2025

Study offers new insight into how nature and nurture shape aggression in males

Like humans, mice will compete over territory and mates, and show increased confidence in their fighting skills the more they win.

24 Jan 2025

New genomic insights could transform bipolar disorder treatment

Study published in Nature identifies nearly 300 genomic regions associated with bipolar disorder, and 36 key genes involved in the disease.

23 Jan 2025

Benefits and risks of popular weight-loss drugs revealed

Demand for weight-loss medications sold under brand names such as Ozempic and Wegovy continues to surge, with a recent study reporting one in eight Americans has taken or is currently using the drugs to treat diabetes, heart disease or obesity.

20 Jan 2025

Researchers create an atlas of health associations for GLP-1 receptor agonists

Insights from a study on GLP-1 receptor agonists reveal benefits for cardiometabolic health, with notable risks for gastrointestinal and musculoskeletal issues.

20 Jan 2025

Immune system changes may predict antipsychotic resistance in schizophrenia Scientis...

Researchers from the National Healthcare Group (NHG)'s Institute of Mental Health (IMH) and Agency for Science, Technology and Research (A*STAR) have made strides in understanding the connection between the immune system and resistance to antipsychotic medications in schizophrenia, using changes in immune cell populations to predict potential treatment resistance and initiate the most appropriate treatment sooner.

16 Jan 2025

High-fat diet linked to impulsive behaviors and brain changes

Researchers examines how a high-fat diet modifies inhibitory control.

14 Jan 2025

Aston University launches initiative to tackle medication-induced weight gain

Dr. Jo Howe and Professor Ian Maidment from Aston Pharmacy School have won funding for a new project to develop new ways to mitigate weight gain caused by antipsychotic medication.

9 Jan 2025

Monoamine neurotransmitters emerge as architects of brain physiology

A collaborative effort between Mount Sinai and Memorial Sloan Kettering Cancer Center has shed valuable light on how monoamine neurotransmitters such as serotonin, dopamine, and now histamine help regulate brain physiology and behavior through chemical bonding of these monoamines to histone proteins, the core DNA-packaging proteins of our cells.

9 Jan 2025

Study reveals how neuropilin2 gene influences autism and epilepsy development

The gene neuropilin2 encodes a receptor involved in cell-cell interactions in the brain and plays a key role in regulating the development of neural circuits.

8 Jan 2025

Differences in brain cell synapses may explain vulnerability to autism and schizophrenia

Specific brain cells known as layer 5 pyramidal neurons play a vital role in how our brains process information.

7 Jan 2025

UCLA professor shares insights into the neurobiology of psychosis risk in adolescents

In a comprehensive Genomic Press Interview, Dr. Carrie E. Bearden, Professor of Psychiatry and Biobehavioral Sciences and Psychology at UCLA, shares transformative insights into the neurobiology of psychosis risk in young people.

7 Jan 2025

Anhedonia: The hidden psychological toll of deep endometriosis

Nearly 30% of women with deep endometriosis experience reduced pleasure sensitivity (anhedonia), linked to chronic pelvic pain, highlighting overlooked psychological consequences of this condition.

6 Jan 2025

New research affirms clozapine safety with minimal blood cancer risk

An inter-departmental research team at the LKS Faculty of Medicine of the University of Hong Kong (HKUMed) has conducted the world's first analytic real-world cohort study on the association of clozapine, a highly efficacious antipsychotic drug, with the incidence of blood cancer.

2 Jan 2025

Professor Inga Neumann advances understanding of oxytocin and social fear

In a comprehensive Genomic Press Interview, Professor Inga Neumann, Chair of the Department of Behavioural and Molecular Neurobiology at the University of Regensburg, reveals groundbreaking insights into how oxytocin shapes social behavior and emotional responses in the brain.

24 Dec 2024

Study finds facial shape differences linked to schizophrenia and bipolar disorder

A study published in Psychiatry Research identifies subtle differences in facial shapes that may be linked to the diagnosis of schizophrenia and bipolar disorder.

19 Dec 2024

Vanderbilt researchers achieve milestone in Alzheimer's drug development

Researchers at the Warren Center for Neuroscience Drug Discovery, a clinical stage biotech within the Vanderbilt University School of Medicine Basic Sciences, have detailed the successful drug discovery of a phase I single ascending dose clinical trial of VU319, a drug for memory loss in people with Alzheimer's disease and schizophrenia.

19 Dec 2024

Nutraceuticals: exploring potential benefits and challenges of an unregulated healthcare frontier

Nutraceuticals offer potential health benefits, from migraine relief to cognitive support, but safety and regulatory issues must be addressed for effective use.

18 Dec 2024

Rage has long shadowed American health care. It’s rarely produced big change.

Among the biggest-grossing films in America in February 2002 were a war drama about American troops in Somalia ("Black Hawk Down"), an Arnold Schwarzenegger action movie ("Collateral Damage"), and a future Oscar winner about a brilliant mathematician struggling with schizophrenia ("A Beautiful Mind").

18 Dec 2024