Schizophrenia

Schizophrenia is a chronic debilitating disorder which affects more than two million Americans, and millions more worldwide. While significant progress has been made in understanding the disease and developing treatments, there remains a significant unmet medical need. More than 50% of patients switch their medication in a given year due to either poor response or the experience of adverse events.

Schizophrenia

Schizophrenia is a chronic mental health disorder that causes people to think, feel and perceive the world differently from the general population.

Schizophrenia Diagnosis

Schizophrenia Causes

Schizophrenia Signs and Symptoms

Schizophrenia Neural Processes

Schizophrenia Mechanisms

Schizophrenia Screening, Prevention and Management

Schizophrenia Medication

Schizophrenia Interventions

Schizophrenia Prognosis

Latest Schizophrenia News and Research

Genetic susceptibility to schizophrenia associated with thinner retinas

A new study led by the University of Zurich has shown that evidence of genetic susceptibility to schizophrenia can be found in the retina. This finding could help improve the early detection of the disorder.

22 Apr 2025

Discovery sheds light on protein's role in myelin formation and schizophrenia

Research published in the Journal of Neurochemistry has detailed the role of a protein, hnRNP A1, in the formation and stability of myelin, suggesting an important impact on neurodegenerative diseases and mental disorders such as multiple sclerosis and schizophrenia.

17 Apr 2025

Researchers simulate protein structures behind learning and memory

Our brain's remarkable ability to form and store memories has long fascinated scientists, yet most of the microscopic mechanisms behind memory and learning processes remain a mystery.

16 Apr 2025

More psych hospital beds are needed for kids, but neighbors say not here

In January, a teenager in suburban St. Louis informed his high school counselor that a classmate said he planned to kill himself later that day.

11 Apr 2025

Mental health disorders more prevalent in people with criminal legal histories

A new national epidemiological survey provides a demographic and diagnostic picture of people living with mental ill health in prison, those with criminal legal involvement in the last year, and those with no criminal legal history in the last year-finding significantly higher rates of five mental health conditions in incarcerated individuals and individuals with recent criminal legal history.

9 Apr 2025

Cannabis users have elevated dopamine levels associated with psychosis

A McGill University-led study found that people with cannabis use disorder (CUD) had elevated dopamine levels in a brain region associated with psychosis.

9 Apr 2025

New award to recognize contributions linking neuroscience to psychiatric diagnosis and treatment

Mental health is in crisis worldwide. While the neurosciences are advancing rapidly, psychiatry still struggles to diagnose and effectively treat many disorders. The Synapsy Center for Neuroscience and Mental Health Research at the University of Geneva, Switzerland, is launching a new international prize to reward those who bring these two worlds closer together.

9 Apr 2025

Gut bacteria may reduce the effectiveness of common medications

A new study, published today in Nature Chemistry by researchers from the University of Pittsburgh and Yale University, shows how common gut bacteria can metabolize certain oral medications that target cellular receptors called GPCRs, potentially rendering these important drugs less effective.

3 Apr 2025

Experts develop new guidelines for the treatment of schizophrenia

New guidelines have been developed for the treatment of schizophrenia after a collaboration of international experts from 30 countries.

2 Apr 2025

New virtual reality system aims to revolutionize psychiatric diagnosis

Researchers have developed a virtual reality-based system that shows promise in improving the differentiation between common mental health conditions, potentially paving the way for earlier and more personalized treatment.

31 Mar 2025

Scientists confirm neurobiochemical link between dopamine and cognitive flexibility

For the first time, scientists have confirmed a neurobiochemical link between dopamine and cognitive flexibility, according to new research published in the March issue of The Journal of Nuclear Medicine.

28 Mar 2025

Discovery provides crucial molecular targets for future obesity treatments

The pleasure we get from eating junk food - the dopamine rush from crunching down on salty, greasy French fries and a luscious burger - is often blamed as the cause of overeating and rising obesity rates in our society.

26 Mar 2025

Genetic and environmental factors in schizophrenia

Schizophrenia affects millions worldwide, yet its causes remain one of the greatest medical mysteries. In an exclusive Genomic Press Interview, Dr. Consuelo Walss-Bass, a pioneering researcher in psychiatric genetics, shares how both genetic predisposition and environmental factors contribute to severe mental health disorders.

26 Mar 2025

Scientists find links between bipolar disorder and rare loss-of-function variants in two genes

Scientists at deCODE genetics, a subsidiary of Amgen, reveal today in Nature Genetics associations between bipolar disorder and rare loss-of-function variants in two genes.

25 Mar 2025

Fatty acids in the blood may predict risk of developing schizophrenia from cannabis use

The UPV/EHU study, recently published in the journal Scientific Reports, has analyzed and compared the fatty acids in the blood of individuals with schizophrenia, of those with cannabis use disorder and of those with both diagnoses, with the aim of shedding light on new biomarkers and improving the understanding of the biological relationship between the two disorders.

21 Mar 2025