Schizophrenia

Schizophrenia is a chronic debilitating disorder which affects more than two million Americans, and millions more worldwide. While significant progress has been made in understanding the disease and developing treatments, there remains a significant unmet medical need. More than 50% of patients switch their medication in a given year due to either poor response or the experience of adverse events.

Schizophrenia

Schizophrenia is a chronic mental health disorder that causes people to think, feel and perceive the world differently from the general population.

Schizophrenia Diagnosis

Schizophrenia Causes

Schizophrenia Signs and Symptoms

Schizophrenia Neural Processes

Schizophrenia Mechanisms

Schizophrenia Screening, Prevention and Management

Schizophrenia Medication

Schizophrenia Interventions

Schizophrenia Prognosis

Latest Schizophrenia News and Research

Gut bacteria may reduce the effectiveness of common medications

A new study, published today in Nature Chemistry by researchers from the University of Pittsburgh and Yale University, shows how common gut bacteria can metabolize certain oral medications that target cellular receptors called GPCRs, potentially rendering these important drugs less effective.

3 Apr 2025

Experts develop new guidelines for the treatment of schizophrenia

New guidelines have been developed for the treatment of schizophrenia after a collaboration of international experts from 30 countries.

2 Apr 2025

New virtual reality system aims to revolutionize psychiatric diagnosis

Researchers have developed a virtual reality-based system that shows promise in improving the differentiation between common mental health conditions, potentially paving the way for earlier and more personalized treatment.

31 Mar 2025

Scientists confirm neurobiochemical link between dopamine and cognitive flexibility

For the first time, scientists have confirmed a neurobiochemical link between dopamine and cognitive flexibility, according to new research published in the March issue of The Journal of Nuclear Medicine.

28 Mar 2025

Discovery provides crucial molecular targets for future obesity treatments

The pleasure we get from eating junk food - the dopamine rush from crunching down on salty, greasy French fries and a luscious burger - is often blamed as the cause of overeating and rising obesity rates in our society.

26 Mar 2025

Genetic and environmental factors in schizophrenia

Schizophrenia affects millions worldwide, yet its causes remain one of the greatest medical mysteries. In an exclusive Genomic Press Interview, Dr. Consuelo Walss-Bass, a pioneering researcher in psychiatric genetics, shares how both genetic predisposition and environmental factors contribute to severe mental health disorders.

26 Mar 2025

Scientists find links between bipolar disorder and rare loss-of-function variants in two genes

Scientists at deCODE genetics, a subsidiary of Amgen, reveal today in Nature Genetics associations between bipolar disorder and rare loss-of-function variants in two genes.

25 Mar 2025

Fatty acids in the blood may predict risk of developing schizophrenia from cannabis use

The UPV/EHU study, recently published in the journal Scientific Reports, has analyzed and compared the fatty acids in the blood of individuals with schizophrenia, of those with cannabis use disorder and of those with both diagnoses, with the aim of shedding light on new biomarkers and improving the understanding of the biological relationship between the two disorders.

21 Mar 2025

Researchers reveal link between placental DNA methylation and neuropsychiatric disorders

An international team led by UPV/EHU and Biobizkaia reveals the relationship between placental DNA methylation and certain neuropsychiatric disorders.

20 Mar 2025

Advanced software improves cerebellum analysis for disease diagnosis

A team of researchers from the Universitat Politècnica de València (UPV) and the French National Centre for Scientific Research (CNRS) has developed the world's most advanced software to study the human cerebellum using high-resolution NMR images.

20 Mar 2025

For seniors with hoarding disorder, a support group helps confront stigma and isolation

A dozen people seated around folding tables clap heartily for a beaming woman: She’s donated two 13-gallon garbage bags full of clothes, including several Christmas sweaters and a couple of pantsuits, to a Presbyterian church.

6 Mar 2025

New study confirms GLP-1 medications are safe for mental health in diabetes

Researchers assess whether GLP-1 receptor agonists increase the risk of suicide, self-harm, or suicidal ideation in type 2 diabetes patients.

2 Mar 2025

The brain-gut microbiota axis: Impact on mental health & potential treatment avenues

To be decided by the editor

From Atlantia Clinical Trials 28 Feb 2025

Patients favor non-invasive neuromodulation for neurological and mental health disorders

A new study, led by experts at the University of Nottingham, has found that patients who need treatment for neurological and mental health disorders, would favour non-invasive neuromodulation interventions over current interventions such as pharmaceutical drugs.

27 Feb 2025

Understanding sex differences in the genetic basis of schizophrenia

A joint research study conducted by the UAB and the UB has analyzed the relation between the genetic risk of having schizophrenia and mild subclinical traits in people of the general population.

26 Feb 2025

Study reveals brain structure variability in schizophrenia

The symptoms of schizophrenia vary greatly from person to person. A new study shows how these differences manifest themselves in the structure of the brain.

26 Feb 2025

New research shows why limits on working memory exist

Working memory is what allows humans to juggle different pieces of information in short-term scenarios, like making a mental grocery list and then going shopping or remembering and then dialing a phone number.

24 Feb 2025

Genetic mutation linked to schizophrenia in both humans and mice

A genetic mutation found in two human patients with schizophrenia also increased schizophrenia-related behaviors in mice with the same mutation, a rare finding of a direct genetic link to psychosis, report researchers at the University of Illinois Urbana-Champaign and colleagues in Massachusetts and Germany.

19 Feb 2025

New AI hub for healthcare and neuromodulation set to launch in Geneva

The University hospitals of Geneva (HUG), the Department of Health and Mobilities (DSM) of the Canton of Geneva and the Wyss Center for Bio and Neuro Engineering enter into a three-party agreement to create an artificial intelligence (AI) reference hub for healthcare and neuromodulation with its inauguration set for the second half of the year.

17 Feb 2025

Diabetes drugs may boost brain health but experts warn of risks

Researchers reviewed 374 studies to explore how GLP-1RAs, originally for diabetes, may impact brain health, finding potential benefits for dementia and addiction but inconsistent results for mood disorders.

16 Feb 2025