Severe Acute Respiratory Syndrome News and Research

Latest Severe Acute Respiratory Syndrome News and Research

COVID-19 mitigation strategies decreased childhood medical mortality in the US

Research examines the impact of pandemic mitigation strategies on childhood mortality during the first year of the COVID-19 pandemic in the United States.

25 Apr 2023

Study reveals survival time of SARS-CoV-2 in wastewater: Implications for public health

Study investigated the survival of SARS-CoV-2 in three wastewater matrices - filtered and unfiltered raw wastewater, and secondary effluent. The time required for inactivation of 90% of SARS-CoV-2 was observed to be 10.4, 10.8, and 18.3 hours for unfiltered raw, filtered raw, and secondary effluent, respectively.

25 Apr 2023

A rapid and affordable in vitro model to test SARS-CoV-2 susceptibility in animal species

Research investigates the susceptibility of seven bat species to SARS-CoV-2 by expressing their ACE2 receptor in a non-permissive avian cell line. The study found that all seven bat species were susceptible to SARS-CoV-2, but the level of virus replication differed between bat species and virus variants.

24 Apr 2023

What are the trends in severe outcomes among patients hospitalized with COVID-19 during the first 2 years of the COVID-19 pandemic?

Researchers documented surveillance across a network of 155 acute care hospitals in Canada between March 15, 2020, and May 28, 2022.

24 Apr 2023

Study identifies an unknown SARS-CoV-2 lineage on three mink farms in Poland

Researchers detected a cryptic severe acute respiratory syndrome coronavirus 2 lineage on mink farms in Poland.

24 Apr 2023

Deciphering immunological imprinting in the context of COVID-19

In a recent article published in the journal Immunity, researchers explained the concept of immunological imprinting and its underlying principles. They also discussed its potential role in the context of coronavirus disease 2019 (COVID-19) vaccines.

24 Apr 2023

Novel self-amplifying RNA vaccine confers durable protection against COVID-19, reduces viral shedding in primate study

A self-amplifying replicon RNA vaccine against SARS-CoV-2 can elicit durable and protective immunity in pigtail macaques, even after neutralizing antibody responses have waned to undetectable levels.

23 Apr 2023

Study reveals CMPK-2 protein-coding gene as a potent inhibitor of flaviviruses

CMPK2 identified as a potential pan-flavivirus inhibitor, restricting virus replication and providing a basis for developing new antiviral treatments.

23 Apr 2023

An exploration of the pathophysiological factors and abnormalities of coagulation of long-COVID

Researchers explored the pathophysiological variables and coagulation abnormalities associated with long coronavirus disease (COVID).

21 Apr 2023

Omicron spike N679K mutation acts as a loss-of-function mutation attenuating SARS-CoV-2 in vitro & in vivo

Researchers explored the impact of a loss-of-function mutation in the SARS-CoV-2 Omicron variants on the expression of the spike protein.

20 Apr 2023

Protective mucosal and systemic immunity provided by a single-dose novel live-attenuated intranasal SARS-CoV-2 vaccine candidate

Researchers explored the protective systemic and mucosal immunity provided by a single dose of a live-attenuated SARS-CoV-2 vaccine candidate.

20 Apr 2023

Study indicates that SARS-CoV-2 has evolved to gain increased replicative fitness and become well-adapted in epithelial cells of human airways

Researchers explored increasing replicative fitness of emerging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants

20 Apr 2023

Protein OCLN found to play crucial role in SARS-CoV-2 cell-to-cell transmission

Research explains how the SARS-CoV-2 virus spreads efficiently by directly infecting neighboring cells through a process called cell-to-cell transmission. The virus uses a protein called occludin (OCLN) to enter the cells and causes syncytium formation, which leads to viral spread.

20 Apr 2023

Combination of fluvoxamine and inhaled budesonide reduces severe COVID-19 in high-risk outpatients

Research reports the results of a randomized, placebo-controlled trial that investigated the effects of combining fluvoxamine and inhaled budesonide for preventing disease progression in high-risk outpatients with COVID-19. The study found that the combination treatment reduced the incidence of severe disease requiring advanced care.

20 Apr 2023

Observational cohort study of long COVID among 2 million elderly adults

Research estimates the incidence of long COVID and long Flu among Medicare patients using the World Health Organization (WHO) consensus definition. The study compares the incidence, symptomatology, and healthcare utilization between long COVID and long flu patients.

20 Apr 2023

Early use of dexamethasone associated with reduced mortality in hospitalized COVID-19 requiring breathing support

In a recent study published in the journal JAMA Network Open, researchers examined the clinical use of dexamethasone for hospitalized patients with coronavirus disease 2019 (COVID-19) respiratory illness and explored the heterogeneity of treatment outcomes across different subgroups.

19 Apr 2023

Severe Acute Respiratory Syndrome News and Research

Latest Severe Acute Respiratory Syndrome News and Research

COVID-19 mitigation strategies decreased childhood medical mortality in the US

Study reveals survival time of SARS-CoV-2 in wastewater: Implications for public health

A rapid and affordable in vitro model to test SARS-CoV-2 susceptibility in animal species

What are the trends in severe outcomes among patients hospitalized with COVID-19 during the first 2 years of the COVID-19 pandemic?

Study identifies an unknown SARS-CoV-2 lineage on three mink farms in Poland

Deciphering immunological imprinting in the context of COVID-19

Novel self-amplifying RNA vaccine confers durable protection against COVID-19, reduces viral shedding in primate study

Study reveals CMPK-2 protein-coding gene as a potent inhibitor of flaviviruses

An exploration of the pathophysiological factors and abnormalities of coagulation of long-COVID

Omicron spike N679K mutation acts as a loss-of-function mutation attenuating SARS-CoV-2 in vitro & in vivo

Protective mucosal and systemic immunity provided by a single-dose novel live-attenuated intranasal SARS-CoV-2 vaccine candidate

Study indicates that SARS-CoV-2 has evolved to gain increased replicative fitness and become well-adapted in epithelial cells of human airways

Protein OCLN found to play crucial role in SARS-CoV-2 cell-to-cell transmission

Combination of fluvoxamine and inhaled budesonide reduces severe COVID-19 in high-risk outpatients

Observational cohort study of long COVID among 2 million elderly adults

Early use of dexamethasone associated with reduced mortality in hospitalized COVID-19 requiring breathing support

Can SARS-CoV-2 infection cause diabetes?

Next-generation vaccine strategies to combat current and emerging SARS-CoV-2 variants

Understanding the probable transmission of SARS-CoV-2 from lion to zookeepers

Assessing the efficacy, safety and tolerability of AXA1125 in long COVID patients

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Severe Acute Respiratory Syndrome News and Research

Latest Severe Acute Respiratory Syndrome News and Research

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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