Sickle Cell Anemia News and Research

Latest Sickle Cell Anemia News and Research

New chemical compound can accelerate stem cell mobilization

The finding has led to the development of a new chemical compound that can accelerate this process (called stem cell mobilization) in mice - which could eventually lead to more efficient stem cell harvesting for human use.

26 Jul 2005

Chemical sealant - poloxamer 188 can repair damage to cardiac muscle cell membrane

A common chemical used in the manufacturing and pharmaceutical industries can repair damage to cardiac muscle cell membranes and prevent heart failure in mice with the genetic mutation that causes Duchenne muscular dystrophy, according to scientists at the University of Michigan Medical School.

18 Jul 2005

Research discovers new deadly link to sickle cell disease

A new study led by a researcher at Children's Hospital & Research Center at Oakland is the first to find that an amino acid deficiency in sickle cell disease is the result of hemolysis, a process where red blood cells rupture and release their contents into the blood stream. Low availability of the amino acid arginine is associated with lung disease and death in adult sickle cell patients.

6 Jul 2005

Scientists discover identifying markers for primitive blood-forming stem cells - simplifies cell identification

Scientists at the University of Michigan Medical School have discovered the biological equivalent of a grocery store bar code on the surface of primitive, blood-forming stem cells in mice. Called hematopoietic stem cells, they give rise to all the different types of specialized cells found in blood.

30 Jun 2005

Hydroxyurea may prevent complications such as organ damage and stunted growth in treatment of sickle cell disease

Treating babies who have sickle cell disease (SCD) with oral liquid hydroxyurea appears to prevent the onset of long-term complications triggered by this disease, according to results of a preliminary study by investigators at St. Jude Children's Research Hospital.

16 Jun 2005

Oral liquid Hydroxyurea promising for long-term use in babies with sickle cell disease

15 Jun 2005

Crystallized molecular machine reveals possible new paths for treating diseases

The crystallized form of a molecular machine that can cut and paste genetic material is revealing possible new paths for treating diseases such as some forms of cancer and opportunistic infections that plague HIV patients.

21 Feb 2005

New advances in sickle cell disease

Excruciating pain episodes, recurrent pneumonias, strokes, severe infections, chronic hemolytic anemia, and secondary pulmonary hypertension are common complications of sickle cell disease, a life-threatening inherited defect in blood that causes normally disc-shaped red blood cells to take on a sickle shape.

6 Dec 2004

Children with sickle cell disease who are at risk for a stroke need ongoing blood transfusions to reduce their risk

“This important study shows the value of continuing periodic blood transfusions in preventing the serious and debilitating consequences of stroke,” says NHLBI Acting Director Barbara Alving. “At the same time, there are risks of chronic transfusions and the decision to continue with this treatment must be made on a case-by-case basis.”

6 Dec 2004

Patients suffering from diseases as varied as Type II diabetes, Alzheimer's, Parkinson's have one thing in common

Patients suffering from diseases as varied as Type II diabetes, Alzheimer's, Parkinson's and dozens of lesser known maladies have one thing in common: they suffer from a large build up of amyloids

5 Oct 2004

NIH opens new hospital totally dedicated to clinical research

This new hospital totally dedicated to clinical research — research involving patients — is the most significant addition to the NIH campus in more than 50 years and provides a unique opportunity for scientists, clinicians, and patients to study and conquer both chronic and acute disease in the 21st century.

22 Sep 2004

Potential new drug for the treatment of sickle cell disease

The results were published in the June 2004 issue of The British Journal of Haematology (BJH). MX-1520 is a prodrug of vanillin, a very popular food additive generally regarded as safe (GRAS) by the FDA.

13 Sep 2004

AAP expands recommendations for annual influenza immunizations to include children ages 6 through 23 months

The American Academy of Pediatrics (AAP) has expanded its recommendations for annual influenza immunizations to include children ages 6 through 23 months, as well as close contacts and caregivers of children under age 2.

3 May 2004

Surprises found In gene variation associated with schizophrenia

Approximately two percent of Caucasians have a gene segment variation that can cause a certain form of schizophrenia. Most people with the variation, known as a polymorphism, do not have the disease. A University of Iowa Health Care study reveals a good prognosis for people who do have this form of schizophrenia.

12 Apr 2004

Children with sickle cell disease are living longer, dying less often from their disease

Children with sickle cell disease, an inherited red blood-cell disorder, are living longer, dying less often from their disease and contracting fewer fatal infections than ever before, researchers at UT Southwestern Medical Center at Dallas report. Their study, which will appear in the June edition of the scientific journal Blood, is the first to evaluate survival rates of children receiving the most modern treatments for sickle cell disease. It's also one of the largest published sickle cell studies to date. Researchers followed more than 700 Dallas-area children with the disease over two decades.

25 Mar 2004

Sickle Cell Anemia News and Research

Latest Sickle Cell Anemia News and Research

New chemical compound can accelerate stem cell mobilization

Chemical sealant - poloxamer 188 can repair damage to cardiac muscle cell membrane

Research discovers new deadly link to sickle cell disease

Scientists discover identifying markers for primitive blood-forming stem cells - simplifies cell identification

Hydroxyurea may prevent complications such as organ damage and stunted growth in treatment of sickle cell disease

Oral liquid Hydroxyurea promising for long-term use in babies with sickle cell disease

Crystallized molecular machine reveals possible new paths for treating diseases

New advances in sickle cell disease

Children with sickle cell disease who are at risk for a stroke need ongoing blood transfusions to reduce their risk

Patients suffering from diseases as varied as Type II diabetes, Alzheimer's, Parkinson's have one thing in common

NIH opens new hospital totally dedicated to clinical research

Potential new drug for the treatment of sickle cell disease

AAP expands recommendations for annual influenza immunizations to include children ages 6 through 23 months

Surprises found In gene variation associated with schizophrenia

Children with sickle cell disease are living longer, dying less often from their disease

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Sickle Cell Anemia News and Research

Latest Sickle Cell Anemia News and Research

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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